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snfilms

Intraday Equity (TCS) Trading - 13 Apr 2021 - 0 views

ShareMarket intradayTrading optionTrading FutureTrading EquityTrading shareTradingClass candlestick swingTrading ScalpingTrading

shared by snfilms on 23 Apr 21 - No Cached
  • snfilms on 23 Apr 21
     
    শেয়ার ট্রেডিং | Intraday #ShareMarket real deal on double bottom pattern break down | #ShareTrading #intraday Student's trading technique of 13 Apr'21 on #equity (TCS). https://bit.ly/38jt53L Contact #snfpa on 9051355050 for online/classroom #ShareTradingCourse and admission detail. #Trainer Sanjib Nath
snfilms

Intraday Student's Deal on equity TCS - 05 May 2021 - 0 views

ShareMarket intradayTrading optionTrading FutureTrading EquityTrading shareTradingClass candlestick pivot

shared by snfilms on 12 May 21 - No Cached
  • snfilms on 12 May 21
     
    শেয়ার ট্রেডিং | Intraday #ShareMarket real deal on price action line break out with daily pivot support | #ShareTrading #intraday student Santu Hela trading technique of 05 May'21 on #equity (TCS). https://bit.ly/38jt53L Contact #snfpa on 9051355050 for online/classroom #ShareTradingCourse and admission detail. #Trainer Sanjib Nath
Nathan Goodyear

Preventing Chronic Disease | Plasma Vitamin D and Biomarkers of Cardiometabolic Disease... - 0 views

www.cdc.gov/...12_0230.htm

vitamin D CRP cardiovascular disease CVD vitamin D

shared by Nathan Goodyear on 18 Jun 13 - No Cached
  • Nathan Goodyear on 18 Jun 13
     
    Higher vitamin D levels associated with lower cardio biomarkers: insulin, insulin resistance, triglycerides, TC, LDL and TC:HDL.  Not found to be associated: glucose, apoliporotein A1 and B, CRP, fibrinogen, and homocysteine.
Nathan Goodyear

Coenzyme Q10 supplementation reduces oxidative stress and increases antioxidant enzyme ... - 0 views

www.ncbi.nlm.nih.gov/...21996047

CoQ10 cardiovascular disease catalase SOD super oxide dismutase MDA CAD coronary artery disease heart health

shared by Nathan Goodyear on 11 Apr 17 - No Cached
  • Nathan Goodyear on 11 Apr 17
     
    CoQ10 supplementation of 150 mg in individuals with CAD found to have increased catalase activity, increased SOD activity, an increased MDA levels.  This reduced oxidative stress, TC, and LDL levels.
Nathan Goodyear

The relationship between endogenous testost... [Eur J Endocrinol. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24394726

Testosterone total cholesterol cholesterol lipids triglycerides LDL HDL men male hormone hormones

shared by Nathan Goodyear on 17 Jan 14 - No Cached
  • Nathan Goodyear on 17 Jan 14
     
    Study finds Testosterone inversely associated with TC, TG, and LDL, but positively associated with HDL.  The evidence on Testosterone and lipids are mixed.  This study shows positive effects all the way around.
Nathan Goodyear

Long-term Safety of Testosterone and Growth Hormone Supplementation: A Retrospective St... - 0 views

www.ncbi.nlm.nih.gov/...PMC3104655

hormones Testosterone growth GH hormone PSA cardiovascular male men

shared by Nathan Goodyear on 25 Sep 13 - No Cached
  • Nathan Goodyear on 25 Sep 13
     
    Retrospective study finds that 2 years of Testosterone and GH do not change metabolic biomarkers, PSA, or disease risk.  LDL and TC were in fact decreased in the study arm without statin therapy.
Nathan Goodyear

Serum sex hormone-binding globulin and test... [Eur J Endocrinol. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24670886

SHBG CVD cardiovascular disease men male hormone hormones CRP cholesterol triglycerides Testosterone

shared by Nathan Goodyear on 31 Mar 14 - No Cached
  • Nathan Goodyear on 31 Mar 14
     
    SHBG positively associated with lower CVD risk profile, CRP, blood pressure, TC, triglycerides..., in young men.  This was found independent of Testosterone.  This is similar to a lot of the research on Metabolic Syndrome as well.
Nathan Goodyear

Testosterone replacement therapy improves i... [Eur J Endocrinol. 2006] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...16728551

low T low Testosterone low T men male hormone hormones Testosterone diabetes hypogonadism visceral fat cholesterol replacement therapy

shared by Nathan Goodyear on 07 Aug 14 - No Cached
  • Nathan Goodyear on 07 Aug 14
     
    In obese men with low T and type 2 diabetes, Testosterone replacement improves insulin sensitivity.  Glycated hemoglobin was also improved.  In this study group, a decrease in visceral adiposity and TC was seen.
Nathan Goodyear

Evaluation of atorvastatin efficacy and toxicity on spermatozoa, accessory glands and g... - 0 views

www.ncbi.nlm.nih.gov/...PMC4114109

statin statin therapy statins sperm men male fertility atorvastatin hormones

shared by Nathan Goodyear on 04 Sep 14 - No Cached
  • Nathan Goodyear on 04 Sep 14
     
    I really don't understand the purpose of this study.  Why give "healthy" men with normal lipids atorvastatin???  The study found a reduction in TC and LDL, but also a reduction in sperm number, decreased sperm vitality, increased sperm morphology, decreased prostatic acid pho sphatases, epididymal neutral alpha-glucosidase and L-carnitine levels resulted.  
Nathan Goodyear

Testosterone Replacement Therapy Improves Metabolic Parameters in Hypogonadal Men with ... - 0 views

onlinelibrary.wiley.com/...full

low T Testosterone Diabetes men male hormones HgbA1c TC total cholesterol cholesterol waist circumference

shared by Nathan Goodyear on 04 Feb 14 - No Cached
  • Nathan Goodyear on 04 Feb 14
     
    Testosterone therapy lowered HgbA1c in poorly controlled Diabetics.  These patients were followed out to 52 weeks.  Testosterone therapy, as is lifestyle change, a long term strategy of Diabetes control.  Studies in controlled Diabetics have not shown a reduction in HgbA1c consistently.  Total cholesterol and waist circumference were also reduced.
Nathan Goodyear

Testosterone Deficiency, Cardiac Health, and Older Men - 0 views

www.hindawi.com/...143763

low T Testosterone obesity type II diabetes diabetes health wellness metabolic syndrome lipids cholesterol hypogonadism TDS testicular dysgenesis syndrome men male hormone hormones prostate cancer

shared by Nathan Goodyear on 12 May 14 - No Cached
  • Studies have shown pharmacological doses of testosterone to relax coronary arteries when injected intraluminally [39] and to produce modest but consistent improvement in exercise-induced angina and reverse associated ECG changes [40]. The mechanism of action is via blockade of calcium channels with effect of similar magnitude to nifedipine
    • Nathan Goodyear
      Nathan Goodyear on 12 May 14
       
      This directly refutes the recent studies (3) that Testosterone therapy increases cardiovascular events.
    • Nathan Goodyear
      Nathan Goodyear on 13 May 14
       
      Testosterone acts as a calcium channel blocker inducing vasodilation.
  • men with chronic stable angina pectoris, the ischaemic threshold increased after 4 weeks of TRT and a recent study demonstrates improvement continuing beyond 12 months [
  • Exercise capacity in men with chronic heart failure increased after 12 weeks
  • ...36 more annotations...
  • Studies have shown an inverse relationship between serum testosterone and fasting blood glucose and insulin levels
  • Medications such as chronic analgesics, anticonvulsants, 5ARIs, and androgen ablation therapy are associated with increased risk of testosterone deficiency and insulin resistance
  • Women with T2D or metabolic syndrome characteristically have low SHBG and high free testosterone
    • Nathan Goodyear
      Nathan Goodyear on 12 May 14
       
      This stands in polar opposite of that with men.
  • Hypogonadism is a common feature of the metabolic syndrome
  • The precise interaction between insulin resistance, visceral adiposity, and hypogonadism is, as yet, unclear but the important mechanisms are through increased aromatase production, raised leptin levels, and increase in inflammatory kinins
  • levels of testosterone are reduced in proportion to degree of obesity
  • Men should be encouraged to combine aerobic exercise with strength training. As muscle increases, glucose will be burned more efficiently and insulin levels will fall. A minimum of 30 minutes exercise three times weekly should be advised
  • Testosterone increases levels of fast-twitch muscle fibres
  • By increasing testosterone, levels of type 2 fibres increase and glucose burning improves
  • Weight loss will increase levels of testosterone
  • studies now clearly show that low testosterone leads to visceral obesity and metabolic syndrome and is also a consequence of obesity
  • In the case of MMAS [43], a baseline total testosterone of less than 10.4 nmol/L was associated with a greater than 4-fold incidence of type 2 diabetes over the next 9 years
  • There is high level evidence that TRT improves insulin resistance
  • Low testosterone predicts increased mortality and testosterone therapy improves survival in 587 men with type 2 diabetes
  • A similar retrospective US study involved 1031 men with 372 on TRT. The cumulative mortality was 21% in the untreated group versus 10% ( ) in the treated group with the greatest effect in younger men and those with type 2 diabetes
  • the presence of ED has been shown to be an independent risk factor, particularly in hypogonadal men, increasing the risk of cardiac events by over 50%
  • A recent online publication on ischaemic heart disease mortality in men concluded optimal androgen levels are a biomarker for survival
  • inverse associations between low TT or FT (Table 2) and the severity of CAD
  • A recent 10 year study from Western Australia involving 3690 men followed up from 2001–2010 concluded that TT and FT levels in the normal range were associated with decreased all-cause and cardiovascular mortality, for the first time suggesting that both low and DHT are associated with all-cause mortality and higher levels of DHT reduced cardiovascular risk
  • TDS is associated with increased cardiovascular and all-cause mortality
  • The effect of treatment with TRT reduced the mortality rate of treated cohort (8.4%) to that of the eugonadal group whereas the mortality for the untreated remained high at 19.2%
  • hypogonadal men had slightly increased triglycerides and HDL
  • Men with angiographically proven CAD (coronary artery disease) have significantly lower testosterone levels [29] compared to controls ( ) and there was a significant inverse relationship between the degree of CAD and TT (total testosterone) levels
  • TRT has also been shown to reduce fibrinogen to levels similar to fibrates
  • men treated with long acting testosterone showed highly significant reductions in TC, LDL, and triglycerides with increase in HDL, associated with significant reduction in weight, BMI, and visceral fat
  • Low androgen levels are associated with an increase in inflammatory markers
  • In the Moscow study, C-reactive protein was reduced by TRT at 30 weeks versus placebo
  • In some studies, a decline in diastolic blood pressure has been observed, after 3–9 months [24, 26] and in systolic blood pressure
  • A decline was noted in IL6 and TNF-alpha
  • No studies to date show an increase in LUTS/BPH symptoms with higher serum testosterone levels
  • TRT has been shown to upregulate PDE5 [65] and enhance the effect of PDE5Is (now an accepted therapy for both ED and LUTS), it no longer seems logical to advice avoidance of TRT in men with mild to moderate BPH.
    • Nathan Goodyear
      Nathan Goodyear on 12 May 14
       
      What about just starting with normalization of Testosterone levels first.
  • Several meta-analyses have failed to show a link between TRT and development of prostate cancer [66] but some studies have shown a tendency for more aggressive prostate cancer in men with low testosterone
    • Nathan Goodyear
      Nathan Goodyear on 12 May 14
       
      And if one would have looked at their estrogen levels, I guarantee they would have been found to be elevated.
  • low bioavailable testosterone and high SHBG were associated with a 4.9- and 3.2-fold risk of positive biopsy
  • Current EAU, ISSAM, and BSSM guidance [1, 2] is that there is “no evidence TRT is associated with increased risk of prostate cancer or activation of subclinical cancer.”
  • Men with prostate cancer, treated with androgen deprivation, develop an increase of fat mass with an altered lipid profile
  • Erectile dysfunction is an established marker for future cardiovascular risk and the major presenting symptom leading to a diagnosis of low testosterone
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