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elevated insulin levels associated with disordered Beta-amyloid metabolism and hyperphosphorylation of tau proteins.  Free radicals also play a role as well.

Can Alzheimer's be prevented?  New study suggests that nutrition, exercise, and healthy weight are key to Alzheimer's prevention.  A decrease in amyloid plaques and tau tangles were noted in normal BMI individuals, those with greater physical activity and those on a mediterranean diet.

SAMe helps to correct disordered homocysteine metabolism due to B- vitamin deficiency found in Alzheimer's disease.  SAMe show to reduce amyloid production, improve memory, decrease Tau, and reduced plaque formation.  Now, this was in a mice model, but SAMe as a methyl donor can benefit clients with dementia with minimal side effects.

4 abstracts highlighting coffee, cinnamon, and chelation in Alzheimer's prevention and treatment

very nice case review and discussion of the treatment of low T and low sperm count in men desiring preservation of fertility.  Clomid and HCG are viable options to increase endogenous Testosterone production, though both work via different mechanisms.

Gut bacteria may play crucial role in systemic inflammation that leads to Alzheimer's and Parkinson's disease.  These amyloid production bacteria trigger systemic inflammation that leads to microglia activation and amyloid in the brain.   More establishment of the gut-brain connection.