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Sean Nash

"I Wonder...": Reconnecting with Our Natural Curiosity - YouTube - 0 views

www.youtube.com/watch

projectdevelopment curiosity wonder nature of science science SCI-I questioning HSRTC SFS potential research idea biology chemistry physics engineering computer science mathematics statistical analysis questions botany environmental HSR HSR-2023

shared by Sean Nash on 23 Jun 23 - No Cached
ryleighnyp liked it
  • Reconnecting with Our Natural Curiosity
    • Sean Nash
      Sean Nash on 23 Jun 23
       
      This is Caitlyn with the Society for Science (the group that sponsors the ISEF & RTS. I saw her give this talk in person last October. she gives some really good suggestions for reconnecting to the curiosity and wonder of your childhood. It is THIS skill that separates the typical student from the creative mind of a scientist. Will YOU try out any of her suggestions??
Sean Nash

Science Daily: News & Articles in Science, Health, Environment & Technology - 3 views

www.sciencedaily.com

science news technology research magazine sciencedaily SCII

shared by Sean Nash on 26 May 23 - No Cached
  • Your source for the latest research news
    • Sean Nash
      Sean Nash on 26 May 23
       
      You'll want this resource...
Sean Nash

Satellite Monitoring of Biodiversity Moves Within Reach | Current Science Daily - 2 views

currentsciencedaily.com/...iodiversity-moves-within-reach

HSR-2023 HSR statistical analysis mathematics computer science botany environmental science biology satellite monitoring biodiversity current potential research idea

shared by Sean Nash on 15 Jun 23 - No Cached
  • Data for the study came from the National Ecological Observatory Network (NEON). The network uses standardized methods to collect biodiversity and Earth observation data across the United States which are then made publicly available. NEON imaging spectrometer data collected from research flights have a pixel size of 1x1 meter.
    • Sean Nash
      Sean Nash on 15 Jun 23
       
      I wonder if any of the imagery they have is: 1. Accessible by us, and 2. Available for our area. If so, it might be as simple as doing plant diversity surveys to look for ground truth in our area (young forests & grasslands) between what is REALLY on the ground here, vs. what the satellite imagery shows.
  • Biodiversity monitoring from space possible via satellite
  • The reflectance of plants is determined by their chemical, anatomical and morphological characteristics, which are important for interactions among plants and with their environment. “Plants with similar traits, as well as closely related species, therefore tend to have similar reflectance spectra,” explains Schweiger.
  • ...1 more annotation...
  • Spectral diversity calculated in forests with closed canopies and large individual trees matched plant diversity determined on the ground better than spectral diversity calculated in open landscapes dominated by small herbaceous plants and grasses.
Sean Nash

Volatile communication in plants relies on a KAI2-mediated signaling pathway | Science - 0 views

www.science.org/...science.adl4685

botany plants communication signaling hormones HSR-2023 HSR environmental questions potential research idea biology

shared by Sean Nash on 22 Mar 24 - No Cached
  • Sean Nash on 22 Mar 24
     
    Yes, plants DO communicate....
Sean Nash

CID Bio-Science Digital Plant Canopy Imager - 0 views

www.forestry-suppliers.com/...ce-digital-plant-canopy-imager

HSR-2023 HSR science environmental botany biology forestry tools equipment potential research idea

shared by Sean Nash on 01 Apr 24 - No Cached
  • Sean Nash on 01 Apr 24
     
    (OMG- this would be anazing)
Sean Nash

Mysterious Underwater Acoustic World of British Ponds Revealed in New Study | Current S... - 3 views

currentsciencedaily.com/...sh-ponds-revealed-in-new-study

hydrophone sound survey pond potential research idea biology physics computer science environmental science HSR HSR-2023

shared by Sean Nash on 04 Jun 23 - No Cached
  • The previously hidden and diverse underwater acoustic world in British ponds has been revealed by a team of researchers at the University of Bristol.
    • Sean Nash
      Sean Nash on 04 Jun 23
       
      So... my immediate thought is: How cool would it be to do this here? One thing we DO have: PONDS. See if this *sounds* interesting. Get it? ;)
  • Acoustic monitoring has been shown to effectively survey birds and monkeys in rainforests, and marine mammals in the oceans. However, freshwater environments have remained largely unexplored despite their diverse soundscapes.
    • Sean Nash
      Sean Nash on 04 Jun 23
       
      BOOM. Again, "relatively unexplored" is super exciting verbiage to me. Acoustics. Hydrophones. Is this feasible? Is the equipment affordable? If not, could we borrow one? Dig into it. What are the possibilities?
  • analysis of the audio files revealed clear daily acoustic activity cycles in each pond
    • Sean Nash
      Sean Nash on 04 Jun 23
       
      Aside from the exploratory surveys you would do just to see "what's out there" and assess what we CAN learn from listening to a pond, you could make it experimental by comparing ponds you've assessed the health of by other means. In other words, do acoustic comparisons between two ponds correlate with what you find by doing a macroinvertebrate sampling? I really LIKE the possibilities in this one!
  • ...3 more annotations...
  • Typically, a nocturnal chorus is made by aquatic insects that compete to attract mates by producing strange scratching sounds as they rub their genitals against their abdomens. During the daytime, however, aquatic plants dominate the underwater orchestra with rhythmic whining and ticking sounds produced as tiny oxygen bubbles are released by plants respiring in the hot sun.
  • Using this acoustic method, the presence of species, and a determination of ecological health, can be inferred simply by listening to the natural world without disturbing the environment or harming the plants and animals within it.
    • Sean Nash
      Sean Nash on 04 Jun 23
       
      Here is the obvious value proposition if you could work this out.
  • Publication: Jack A. Greenhalgh, et al., Diel variation in insect-dominated temperate pond soundscapes and guidelines for survey design, Freshwater Biology (2023). DOI: 10.1111/fwb.14092.
    • Sean Nash
      Sean Nash on 04 Jun 23
       
      BEST THING YET: Here is the FULL TEXT of the actual research paper!
ryleighnyp

Watch ticks fly through the air via the power of static electricity | Science | AAAS - 1 views

www.science.org/...h-air-power-static-electricity

potential research idea HSR HSR-2023

shared by ryleighnyp on 26 Jul 23 - No Cached
    • ryleighnyp
      ryleighnyp on 26 Jul 23
       
      It would be fascinating to find something that could prevent that static electricity, especially on pets. I feel like there are lots of possibilities with this.
katherine-medina

Peptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resi... - 0 views

www.science.org/...sciadv.adg3683

bacteria-killing HSR2023 peptide drug-resistant thanatin

shared by katherine-medina on 05 Aug 23 - No Cached
  • Recently, naturally occurring peptides were proposed to interfere with the function of proteins constituting the lipopolysaccharide
  • periplasmic
    • katherine-medina
      katherine-medina on 05 Aug 23
       
      The space in between the inner and outer membranes of gram-negative bacteria
  • Thanatin, a 21–amino acid defense peptide isolated from the gut of the hemipteran insect Podisus maculiventris (18), exhibits broad-spectrum antimicrobial activity
    • katherine-medina
      katherine-medina on 05 Aug 23
       
      I wonder what other peptides do so as well?
  • ...7 more annotations...
  • We hypothesized that thanatin mainly acts as a competitive inhibitor of the protein-protein interactions mediating the Lpt bridge assembly
  • Thanatin, however, is not a suitable drug candidate for further development due to poor drug-like properties and rapid emergence of resistance
    • katherine-medina
      katherine-medina on 05 Aug 23
       
      Why/How does thanatin have poor drug-like properties?
  • β-jellyroll
    • katherine-medina
      katherine-medina on 05 Aug 23
       
      structure found in proteins
  • Here, we introduce thanatin-derived synthetic macrocyclic peptides found after a substantial medicinal chemistry effort.
    • katherine-medina
      katherine-medina on 05 Aug 23
       
      Essentially they synthetically created it
  • Development of resistance against thanatin was observed after 1 day of passaging in both E. coli and K. pneumoniae and is characterized by a spontaneous FOR of 1.2 × 10−6 for E. coli at 4× MIC
    • katherine-medina
      katherine-medina on 05 Aug 23
       
      That is kinda scary to think about
  • genome sequencing of a diverse panel of thanatin-resistant strains confirmed on-target modifications on LptA as the main resistance determinant in E. coli and K. pneumoniae.
  • The attractive in vitro and in vivo profile of these new antibiotics, coupled with their novel mechanism of action, showing no cross-resistance to standard of care antibiotics, may provide clinicians with additional treatment options to fight AMR, either in combination with SoC or as stand-alone antibiotics.
    • katherine-medina
      katherine-medina on 05 Aug 23
       
      It is interesting to look around that these other methods that can fight off bacteria.
  • katherine-medina on 05 Aug 23
     
    An article showing a new class of antibiotics known as a peptidomimetic antibiotic.
katherine-medina

Sci-Hub | A droplet-based electricity generator with high instantaneous power density. ... - 0 views

sci-hub.se/...s41586-020-1985-6

water-power droplets electricity HSR-2023

shared by katherine-medina on 22 Aug 23 - No Cached
    • katherine-medina
      katherine-medina on 22 Aug 23
       
      We find that when a falling water droplet spreads on the PTFE surface, it bridges the originally disconnected components (the PTFE/ITO and aluminum electrode) into a closed-loop, electrical system Interesting.
    • katherine-medina
      katherine-medina on 22 Aug 23
       
      Fig. 1 | Design of the DEG. a, Schematic diagram. b, Optical image showing four parallel DEG devices fabricated on a glass substrate. The volume of each droplet is 100.0 μl. c, As individual droplets continue to impinge on the asfabricated device, the amount of charge on the PTFE surface increases gradually and eventually reaches a stable value. d, One hundred commercial LEDs can be powered when one droplet, released from a height of 15.0 cm, is in contact with the device. e, Under the same experimental conditions (for example, the same droplet size and height of release), the output voltage measured from the DEG (in red, with the frequency of impinging droplets being
  • katherine-medina on 22 Aug 23
     
    Interesting to see a different method on creating power out of water. I kinda of want to look into the science of water.
Sean Nash

E-learning courses - GrowNextGen - 2 views

grownextgen.org/elearning

agriculture food foodscience courses SCI-I topicselection resources learning research ideas environmental science botany biology HSR HSR-2023

shared by Sean Nash on 23 Jun 23 - No Cached
  • These self-guided digital resources allow students to work independently. Pre- and posttests can be used to check knowledge gains.
    • Sean Nash
      Sean Nash on 23 Jun 23
       
      An interesting set of open online courses to take your learning to the next level in some area... These might be interesting early on in the problem-finding phase, but also once a topic is chosen... you need to get up to speed in an area of science much more quickly than in traditional teacher-led courses. Perhaps one of these can help you build early background expertise in some area?
katherine-medina

Increased 3-O-sulfated heparan sulfate in Alzheimer's disease brain is associated with ... - 1 views

www.science.org/...sciadv.adf6232

Alzheimer's-disease Research-idea brain HSR-2023 Human

shared by katherine-medina on 27 May 23 - No Cached
  • Genetic factors contribute substantially to the pathological process of AD as demonstrated by the fact that the genetic heritability in AD is in the range of between 60 and 80% (10).
  • however, whether the variants alter the level of 3-OST-1 enzyme activity to change the structure of HS remains unknown
    • katherine-medina
      katherine-medina on 27 May 23
       
      Good to note what exactly the article remains unsure about
  • The synthesis of additional 13C-labeled calibrants to cover these three reported 3-O-sulfated tetrasaccharides will be the subject for future study.
    • katherine-medina
      katherine-medina on 27 May 23
       
      LOOK INTO THIS PART CAYSE THEY ARE SAYING THAT THEY ARE NOT FULLY SURE
  • ...4 more annotations...
  • the elevation of total HS and the percentage of the 3-O-sulfated domain in HS.
  • HS and tau revealed that the sugar mainly interacts with the proline-rich region 2, a repeat domain 2 in tau protein
  • Further analysis of the distribution of 3-O-sulfated HS from different areas of AD brains will be of interest and the subject for a subsequent study.
  • Experimental design
    • katherine-medina
      katherine-medina on 27 May 23
       
      READ THIS IF THIS TOPIC COMES BACK UP AGAIN
  • katherine-medina on 27 May 23
     
    A interesting study about a sulfate that suggests that Alzheimer's is genetic
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