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Sean Nash

Shining the Light on Baby Crabs | Hakai Magazine - 2 views

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    I added this one, which includes detail of an environmental study, to illustrate how creative use of everyday materials can sometimes work to design scientific methods that work!
Sean Nash

Microwaving an insecticide restores its mosquito-killing power - 2 views

  • Heating an insecticide can give it new life.
    • Sean Nash
       
      Wait, what? Do say more.....
  • Microwaving the insecticide deltamethrin rearranges its crystal structure but doesn’t change its chemical composition. The rearrangement renews deltamethrin’s ability to kill mosquitoes that have become resistant to the insecticide, researchers report April 21 in Malaria Journal.
    • Sean Nash
       
      Hmmmm... something similar to this smells like: feasibility.
  • The microwave worked just as well, but Kahr cautions that people shouldn’t use the same microwave for heating food and insecticides.
    • Sean Nash
       
      Ha! No kidding??
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  • insecticide resistance is a growing problem
  • It is encouraging that heated insecticide killed highly resistant mosquitoes, says Hemingway, who directs the Infection Innovation Consortium, a public-private effort to find new ways to combat infectious diseases. But, she says, “this is not something we can take and use that tomorrow.”
    • Sean Nash
       
      OK.... this is how you can find an opening (not saying THIS ONE is necessarily, but, when you see language like: "we can't really do it just yet," that is a screaming opportunity to see what we MIGHT be able to add to that.
  • It’s not certain that the heat-treated deltamethrin would retain its more potent crystal structure through the net-making process.
  • Kahr’s team is working on incorporating the heat-treated crystal into nets.
  • “There are all kinds of social and cultural things that you could propose from a scientific perspective that wouldn’t be welcomed by a community of homeowners.”
    • Sean Nash
       
      Again... this reads: "potential research opportunity."
  • Kahr and colleagues previously discovered that heating deltamethrin changed its crystal structure, which let it work faster
Sean Nash

New patch might replace some finger-prick testing of blood sugar - 2 views

  • Teen’s color-changing device tests glucose in sweat to signal when insulin is needed
    • Sean Nash
       
      This is from a 2023 ISEF project just last week!
elijahjenkins

Fluorine-based new drug synthesis at lightning speed -- ScienceDaily - 0 views

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    Researchers synthesize fluorine-based compound via rapid biphasic (gas and liquid) mixing.
izzy kelly

Study finds brain connectivity, memory improves in older adults after walking -- Scienc... - 0 views

  • They become disconnected, and as a result, people lose their ability to think clearly and remember things. We're demonstrating that exercise training strengthens these connections."
  • walking may decrease cerebral blood flow and improve brain function in older adults with mild cognitive impairment.
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    correlation between exercise and memory. i'd be interested to see the long-term effects.
izzy kelly

Further link identified between autoimmunity and schizophrenia -- ScienceDaily - 0 views

  • Synaptic adhesion proteins are specialized proteins that bind to create physical connections between brain cells
  • utoantibodies against the synaptic protein neurexin 1α,
  • which is expressed by one cell in the synapse and binds to proteins known as neuroligins on the other cell in the synapse,
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  • neurexin 1α can cause schizophrenia-related changes, at least in mice,
  • autoantibodies is important for improving symptom control
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    autoantibodies that target neurexin 1a could possibly play a role in the development of schizophrenia. possible treatment with identifying autoantibodies
Sean Nash

Race car drivers tend to blink at the same places in each lap - 4 views

  • The world goes dark for about one-fifth of a second every time you blink, a fraction of an instant that’s hardly noticeable to most people. But for a Formula One race car driver traveling up to 354 kilometers per hour, that one-fifth means almost 20 meters of lost vision
  • People are often thought to blink at random intervals, but researchers found that wasn’t the case for three Formula drivers.
  • the drivers tended to blink at the same parts of the course during each lap, cognitive neuroscientist Ryota Nishizono and colleagues report in the May 19 iScience
    • Sean Nash
       
      Interesting. So, do we do the same thing while driving around town? Could you design a method to record eye blinks as people drive known routes around town? We could simultaneously use the Arduino Science Journal app on the iPhone to also correlate physical data in a moving car like acceleration/deceleration, motion in X, Y, Z directions, etc. I wonder if we could find a correlation in everyday driving that could help from a safety perspective?
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  • He was surprised to find almost no literature on blinking behavior in active humans even though under extreme conditions like motor racing or cycling
    • Sean Nash
       
      OK, now this SCREAMS: "potential research idea."
  • Nishizono and colleagues mounted eye trackers on the helmets of three drivers and had them drive three Formula circuits
  • Where the drivers blinked was surprisingly predictable, the team found. The drivers had a shared pattern of blinking that had a strong connection with acceleration, such that drivers tended not to blink while changing speed or direction — like while on a curve in the track — but did blink while on relatively safer straightaways.
    • Sean Nash
       
      What sort of implications does this have for driving in key, known, busy interchanges in KC? Could we potentially provide data to show certain stretches of highway need more signage, etc? That could have civil engineering implications.
  • “We think of blinking as this nothing behavior,” he says, “but it’s not just wiping the eyes. Blinking is a part of our visual system.”
  • Nishizono next wants to explore what processes in the brain allow or inhibit blinking in a given moment, he says, and is also interested in how blinking behavior varies among the general population.
    • Sean Nash
       
      While the "brain" part might move beyond our feasibility, the potential of finding real correlations to driving patterns or routes is a completely different spin-off and one that could have really practical suggestive applications for city planners, etc.
Sean Nash

Mysterious Underwater Acoustic World of British Ponds Revealed in New Study | Current S... - 3 views

  • The previously hidden and diverse underwater acoustic world in British ponds has been revealed by a team of researchers at the University of Bristol.
    • Sean Nash
       
      So... my immediate thought is: How cool would it be to do this here? One thing we DO have: PONDS. See if this *sounds* interesting. Get it? ;)
  • Acoustic monitoring has been shown to effectively survey birds and monkeys in rainforests, and marine mammals in the oceans. However, freshwater environments have remained largely unexplored despite their diverse soundscapes.
    • Sean Nash
       
      BOOM. Again, "relatively unexplored" is super exciting verbiage to me. Acoustics. Hydrophones. Is this feasible? Is the equipment affordable? If not, could we borrow one? Dig into it. What are the possibilities?
  • analysis of the audio files revealed clear daily acoustic activity cycles in each pond
    • Sean Nash
       
      Aside from the exploratory surveys you would do just to see "what's out there" and assess what we CAN learn from listening to a pond, you could make it experimental by comparing ponds you've assessed the health of by other means. In other words, do acoustic comparisons between two ponds correlate with what you find by doing a macroinvertebrate sampling? I really LIKE the possibilities in this one!
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  • Typically, a nocturnal chorus is made by aquatic insects that compete to attract mates by producing strange scratching sounds as they rub their genitals against their abdomens. During the daytime, however, aquatic plants dominate the underwater orchestra with rhythmic whining and ticking sounds produced as tiny oxygen bubbles are released by plants respiring in the hot sun.
  • Using this acoustic method, the presence of species, and a determination of ecological health, can be inferred simply by listening to the natural world without disturbing the environment or harming the plants and animals within it.
    • Sean Nash
       
      Here is the obvious value proposition if you could work this out.
  • Publication: Jack A. Greenhalgh, et al., Diel variation in insect-dominated temperate pond soundscapes and guidelines for survey design, Freshwater Biology (2023). DOI: 10.1111/fwb.14092.
    • Sean Nash
       
      BEST THING YET: Here is the FULL TEXT of the actual research paper!
Sean Nash

Regeneron ISEF 2023 - Finalist Project Portal - 6 views

  • Choose a category to begin
    • Sean Nash
       
      This is a really good way to dive into specific categories and explore the projects that made it to this year's ISEF. What I would do is start with what immediately interests you for now... and pick up some tips. You might get ideas for areas/topics to research. You might see creative methods used in various studies. Pay particular attention to the fact that some utilize equipment only available at a university or corporate lab, but... many also feature creative methods done by students at home or in school labs as well!
    • Sean Nash
       
      Once you get inside projects that you get ideas from, feel free to save them in Diigo for later, or share really interesting ones with others you think might benefit from seeing it.
    • Sean Nash
       
      One final thing: you might also get some tips for elements of their presentation that appeal to you.
ryleighnyp

Watch ticks fly through the air via the power of static electricity | Science | AAAS - 1 views

    • ryleighnyp
       
      It would be fascinating to find something that could prevent that static electricity, especially on pets. I feel like there are lots of possibilities with this.
Sean Nash

Red algae reduces methane emissions from cow poop - 1 views

  • Adding the algae to decomposing feces might reduce methane emission from cow agriculture
    • Sean Nash
       
      Here's a bit of an engineering problem..... but one with a biological/ecological frame. The article presents promise, but many challenges. Could you imagine a way to sidestep any of the challenges presented here? What other ways could the methane production issue be strategically mitigated?
Sean Nash

Taurine slows aging in mice. Will it ever work for people? - 1 views

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    Interesting bit on the potential benefits of taurine in the diet. Don't rush out and start an energy drink habit, but if you've had one, you likely know the unique taste of this chemical. There are a ton of things mentioned in this short article. Perhaps dig into what we already know about biochemical pathways of taurine...
Sean Nash

Learning in Plants: Lessons from Mimosa pudica - 4 views

  • there is a lack of observational data on the behavior of plants
  • Observational research allows the researcher to establish baseline activity and response levels of the subject
  • Perhaps the first study of learning in plants was a habituation experiment reported by Pfeffer (1873) using the sensitive plant Mimosa. In this experiment, repeated mechanical stimulation of leaflets led to a decrease in sensitivity
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  • the question naturally arises as to whether Mimosa can discriminate between stimuli. This was answered in the affirmative by Holmes and Gruenberg (1965) whose experimental design included a drop of water and finger touch as stimuli
  • the results suggest that Mimosa can discriminate between stimuli
  • Thomas performed an experiment on classical conditioning in Mimosa that took advantage of the finding that, under field conditions, the leaflets of Mimosa slowly drop as dusk approaches and slowly rise at dawn (personal communication). In the experiment, the CS was turning on the light in the growth chamber and the US was touching selected leaflets. Thomas found that leaflets in the paired condition showed conditioning compared to a light only or alternating stimulation condition. This finding should be replicated with controls for pseudoconditioning.
  • Given the importance of the Gagliano et al. (2014) experiment and the failure to replicate some previous experimental results it is critical that the Gagliano et al. (2014) results be repeated by an independent laboratory.
  • In addition to Mimosa, habituation has been found in the carnivorous plant Drosera (sundew
  • Applewhite (1975) cites an experiment by Darwin reportedly showing habituation in the passion flower (Passiflora gracilis). During this experiment, when Darwin mechanically stimulated the passion flower tendrils, the tendrils no longer responded after 54 h of training.
  • Abramson et al. (2002) investigated the use of bioelectrical potentials as a method to explore plant behavior.
  • In an interesting article, Karpinski and Szechynska-Hebda (2010) discuss the intellect of plants from memory to intelligence. By studying recall, the researcher investigates a host of independent variables and that are solidly anchored to a set of dependent variables. This study focused on recall at the cellular level rather than as an externally observable behavior. The discussion of plant learning at various levels, from cellular to organismal and from different scientific fields is exactly what is advocated for in this article
  • There is also interest from behavioral scientists seeking to determine whether the similarities and differences in learning found among invertebrates and vertebrates could also be found in plants (Warden et al., 1940; Applewhite, 1975; Abramson et al., 2002; Guiguet, 2013).
  • The majority of early plant studies used the Sensitive plant (M. pudica). Mimosa has much to recommend it for learning studies. They are easy to maintain, much is known about its natural history, and they have a visible leaf closure response to external stimuli. However, there are drawbacks in the use of Mimosa, for example, it takes about 15 min for a leaf to recover (Holmes and Gruenberg, 1965) and not much is known about its genome in contrast to model species such as Arabidopsis thaliana whose entire genome is known.
  • In the following section we will focus on methods to develop studies utilizing habituation, sensitization, and classical conditioning techniques. Instrumental and operant conditioning will not be covered because at this time there are no Mimosa studies in these areas; although one can envision a situation where the opening and closing of a leaf can be detected electronically. Once detected, the response would produce a consequence such as an airpuff or changes in light intensity.
    • Sean Nash
       
      The remainder of this comprehensive article is to outline the main lines of research in this area:
  • Learning in Plants: Lessons from Mimosa pudica
    • Sean Nash
       
      This well-compiled article does a really nice job of outlining the history of study regarding plant behavior. It also suggests model organisms for study. Mimosa is a favorite of mine as their response is VERY rapid and quite visible for a plant! There are all sorts of feasible project ideas that could arise from this area of research.
Sean Nash

Hand dryers can infect clean hands with bathroom germs - 3 views

  • In tests, the hot-air machines spread far more microbes than paper towels
    • Sean Nash
       
      Another ISEF project from just last week!
Grant Reed

Study Finds Carrying Pollen Heats Up Bumble Bees, Raising New Climate Change Questions - 3 views

  • This new understanding of active bumble bee body temperatures raises questions about how these species will be impacted by a warmer world due to climate change.
    • Grant Reed
       
      Trying out the highlight feature. This might be an interesting research topic.
ryleighnyp

The effects of grounding (earthing) on inflammation, the immune response, wound healing... - 2 views

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    This is something I'm interested in and it has lots of potential for projects.
ryleighnyp

Electrical grounding technique may improve health outcomes of NICU babies -- ScienceDaily - 2 views

  • "What we can conclude is that a baby's autonomic nervous system is able to sense the electrical environment and it seems as though a baby is more relaxed when grounded,"
  • redesigning incubators to ground babies and cancel out the electrical field
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    I think a possible research idea could be redesigning NICU incubators to allow for less electromagnet interference with the babies with the use of grounding.
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    Interesting, for sure. Two things... the actual measurements they made on children (skin tests, etc.) are a no-go for us. I'm not sure what our model system could be for checking the electrical outputs of whatever design changes were made. We would need to know a lot more about the current setup in NICUs. There is no doubt a lot of design in how things are currently set up. Essentially: why things are set up the way they are right now? You would have to know every variable currently considered, and then look for spots where simple changes can be made. Second thing: go back to the ISEF categories in Engineering and check out how those projects look at the national level. Just go get a feel. Engineering is a bit different from typical "hypothesis testing" seen in most natural sciences. Very cool, but different. Give it a look.
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