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Sean Nash

Regeneron ISEF 2023 - Finalist Project Portal - 6 views

  • Choose a category to begin
    • Sean Nash
       
      This is a really good way to dive into specific categories and explore the projects that made it to this year's ISEF. What I would do is start with what immediately interests you for now... and pick up some tips. You might get ideas for areas/topics to research. You might see creative methods used in various studies. Pay particular attention to the fact that some utilize equipment only available at a university or corporate lab, but... many also feature creative methods done by students at home or in school labs as well!
    • Sean Nash
       
      Once you get inside projects that you get ideas from, feel free to save them in Diigo for later, or share really interesting ones with others you think might benefit from seeing it.
    • Sean Nash
       
      One final thing: you might also get some tips for elements of their presentation that appeal to you.
Sean Nash

New patch might replace some finger-prick testing of blood sugar - 2 views

  • Teen’s color-changing device tests glucose in sweat to signal when insulin is needed
    • Sean Nash
       
      This is from a 2023 ISEF project just last week!
Sean Nash

Hand dryers can infect clean hands with bathroom germs - 3 views

  • In tests, the hot-air machines spread far more microbes than paper towels
    • Sean Nash
       
      Another ISEF project from just last week!
ryleighnyp

BMED010 - Natural and Commercial Moisturizers on Skin Model | Regeneron ISEF 2023 - 2 views

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    This is a good example of data collection, experimental design, and presentation.
katherine-medina

Full article: Effect of Dandelion root extract on growth performance, immune function a... - 0 views

  • From days 12 to 14 and days 26 to 28, approximately 100 g of faeces was collected from each pen for 3 days and the faecal samples were stored at −20°C. The 3-d faecal collection was pooled by pen and then dried at 65°C for 72 h.
  • From days 12 to 14 and days 26 to 28, approximately 100 g of faeces was collected from each pen for 3 days and the faecal samples were stored at −20°C. The 3-d faecal collection was pooled by pen and then dried at 65°C for 72 h.
    • katherine-medina
       
      Kinda gross, but interesting to know how and when the collected the "feces."
  • There were no differences in the ATTD of GE, CP, NDF and ADF among the three treatments.
    • katherine-medina
       
      Interesting that there was no difference between the three groups in that category.
  • ...10 more annotations...
  • uring days 15–28, pigs in the CHE group had lower (P < .05) diarrhoea frequency compared with those in the NC treatment, and dietary CHE supplementation decreased the diarrhoea frequency by 63.62% and 57.82% compared with the NC and PC groups, respectively
    • katherine-medina
       
      So the Chinese herbal extract did a better job at reducing the diarrhoea frequency by 63.62 and 57.82% in comparison to the NC and PC groups.
  • Moreover, the concentration of IL-6 in serum in pigs fed the CHE diet was greater (P < .05) than those fed the NC diet.
  • There were no differences in the concentrations of IgA, IgG, IgM, GSH-PX, MDA, TNF-α, IL-4 and IL-1β among the three treatments.
  • Furthermore, pigs in the CHE group had greater (P < .05) formic acid, propionate and butyrate concentrations in faeces compared with pigs in the PC group, and had greater (P < .05) formic acid, butyrate and valerate concentrations in faeces compared with pigs in the NC group
    • katherine-medina
       
      Cool to note that the CHE group had a lower lactic acid concentration in comparison to the PC group.
  • Pigs in the CHE group showed increased relative abundance of Sytrophococcus on genus level, and decreased (P < .05) relative abundance of Clostridiaceae_1
  • In addition, relative abundances of genus Selenomonas, Alloprevotella, Prevotella_2, Rjkenellaceae, and Kitasatospora all increased in faecal samples when pigs fed the PC diet.
  • CHE supplementation decreased the diarrhoea frequency of pigs compared with diets with or without antibiotics supplemented. Some previous studies also reported the positive effects of dietary Chinese herbs supplementation on diarrhoea frequency of weaned pigs
  • he increased concentrations of immune markers in serum and faecal SCFAs in weaned pigs consumed CHE in our study may explain the positive effects of CHE supplementation on diarrhoea frequency and nutrient digestibility
  • but decreased the incidence of diarrhoea and increased digestibility of some nutrients.
  • In addition, CHE supplementation improved faecal SCFAs concentrations and immune function of weaned pigs, and shaped faecal microbial community in weaned pigs. As a result, the traditional Chinese herb medicine, CHE, could act as a potential alternative to the antibiotics such as aureomycin used in weaned pig diets.
    • katherine-medina
       
      I do quite enjoy this closing statement, so in summary CHE works to decrease diarrhoea in weened pigs.
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    An article showing that pigs who ate CHE had a significant decrease in diahrroea.
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    Super interesting. Just remember that experimentation on mammals where diet is altered, etc... is a super tightrope walk. It is almost impossible to get those approved. You would have to really dig into the ISEF rules on that. However, you can always think about ways to transfer ideas and concepts down to a "lower" animal model for many studies.
ryleighnyp

Electrical grounding technique may improve health outcomes of NICU babies -- ScienceDaily - 2 views

  • "What we can conclude is that a baby's autonomic nervous system is able to sense the electrical environment and it seems as though a baby is more relaxed when grounded,"
  • redesigning incubators to ground babies and cancel out the electrical field
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    I think a possible research idea could be redesigning NICU incubators to allow for less electromagnet interference with the babies with the use of grounding.
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    Interesting, for sure. Two things... the actual measurements they made on children (skin tests, etc.) are a no-go for us. I'm not sure what our model system could be for checking the electrical outputs of whatever design changes were made. We would need to know a lot more about the current setup in NICUs. There is no doubt a lot of design in how things are currently set up. Essentially: why things are set up the way they are right now? You would have to know every variable currently considered, and then look for spots where simple changes can be made. Second thing: go back to the ISEF categories in Engineering and check out how those projects look at the national level. Just go get a feel. Engineering is a bit different from typical "hypothesis testing" seen in most natural sciences. Very cool, but different. Give it a look.
Sean Nash

"I Wonder...": Reconnecting with Our Natural Curiosity - YouTube - 0 views

  • Reconnecting with Our Natural Curiosity
    • Sean Nash
       
      This is Caitlyn with the Society for Science (the group that sponsors the ISEF & RTS. I saw her give this talk in person last October. she gives some really good suggestions for reconnecting to the curiosity and wonder of your childhood. It is THIS skill that separates the typical student from the creative mind of a scientist. Will YOU try out any of her suggestions??
Sean Nash

Powerpoint poster templates for research poster presentations - 0 views

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    (BE SURE TO ONLY USE the 36"x48" TRIFOLD templates)
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