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Sean Nash

How patient-led research could speed up medical innovation - 0 views

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    This makes me think of my Mom and her struggle with migranes. She would benefit from a simple iOS app that helps her track symptoms & potential triggers in a way that could easily be shared with her doctor.
Isabella Tungjaroenkul

The new human pangenome could help unveil the biology of everyone - 0 views

  • Being able to assess where some people have extra DNA and others are missing DNA, called structural variants, adds a more nuanced view of human genetics, O’Connor says, revealing more of its complexity (SN: 4/10/09).
  • Conversely, another study found that the very short arms of certain chromosomes, including chromosomes 13, 14 and 21, are becoming more like each other as they swap DNA.
Sean Nash

Race car drivers tend to blink at the same places in each lap - 4 views

  • The world goes dark for about one-fifth of a second every time you blink, a fraction of an instant that’s hardly noticeable to most people. But for a Formula One race car driver traveling up to 354 kilometers per hour, that one-fifth means almost 20 meters of lost vision
  • People are often thought to blink at random intervals, but researchers found that wasn’t the case for three Formula drivers.
  • the drivers tended to blink at the same parts of the course during each lap, cognitive neuroscientist Ryota Nishizono and colleagues report in the May 19 iScience
    • Sean Nash
       
      Interesting. So, do we do the same thing while driving around town? Could you design a method to record eye blinks as people drive known routes around town? We could simultaneously use the Arduino Science Journal app on the iPhone to also correlate physical data in a moving car like acceleration/deceleration, motion in X, Y, Z directions, etc. I wonder if we could find a correlation in everyday driving that could help from a safety perspective?
  • ...5 more annotations...
  • He was surprised to find almost no literature on blinking behavior in active humans even though under extreme conditions like motor racing or cycling
    • Sean Nash
       
      OK, now this SCREAMS: "potential research idea."
  • Nishizono and colleagues mounted eye trackers on the helmets of three drivers and had them drive three Formula circuits
  • Where the drivers blinked was surprisingly predictable, the team found. The drivers had a shared pattern of blinking that had a strong connection with acceleration, such that drivers tended not to blink while changing speed or direction — like while on a curve in the track — but did blink while on relatively safer straightaways.
    • Sean Nash
       
      What sort of implications does this have for driving in key, known, busy interchanges in KC? Could we potentially provide data to show certain stretches of highway need more signage, etc? That could have civil engineering implications.
  • “We think of blinking as this nothing behavior,” he says, “but it’s not just wiping the eyes. Blinking is a part of our visual system.”
  • Nishizono next wants to explore what processes in the brain allow or inhibit blinking in a given moment, he says, and is also interested in how blinking behavior varies among the general population.
    • Sean Nash
       
      While the "brain" part might move beyond our feasibility, the potential of finding real correlations to driving patterns or routes is a completely different spin-off and one that could have really practical suggestive applications for city planners, etc.
Sean Nash

Regeneron ISEF 2023 - Finalist Project Portal - 6 views

  • Choose a category to begin
    • Sean Nash
       
      This is a really good way to dive into specific categories and explore the projects that made it to this year's ISEF. What I would do is start with what immediately interests you for now... and pick up some tips. You might get ideas for areas/topics to research. You might see creative methods used in various studies. Pay particular attention to the fact that some utilize equipment only available at a university or corporate lab, but... many also feature creative methods done by students at home or in school labs as well!
    • Sean Nash
       
      Once you get inside projects that you get ideas from, feel free to save them in Diigo for later, or share really interesting ones with others you think might benefit from seeing it.
    • Sean Nash
       
      One final thing: you might also get some tips for elements of their presentation that appeal to you.
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