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Nathan Goodyear

Hypnotics' association with mortality or cancer: a matched cohort study -- Kripke et al... - 0 views

bmjopen.bmj.com/...e000850.full

sleep aids death mortality hypnotics cancer

shared by Nathan Goodyear on 30 Oct 12 - No Cached
  • Nathan Goodyear on 30 Oct 12
     
    prescription sleep aids and hypnotics associated with 3 fold increase in death.  Scary thought considering how many use sleep aids today.  First do no harm is suppose to be a physician's moto.
Nathan Goodyear

Salivary testosterone diurnal variation and psychopathology in adolescent males and fem... - 0 views

www.researchgate.net/...nces_and_developmental_effects

saliva salivary testosterone hormones hormone

shared by Nathan Goodyear on 30 Oct 12 - No Cached
  • Nathan Goodyear on 30 Oct 12
     
    low testosterone in boys associated with anxiety/depression and attention problems.  Disruptive behavior found in girls with low testosterone.  All determined by salivary testing.
Nathan Goodyear

Chewing gum has large effects on salivary testosterone, estradiol, and secretory immuno... - 0 views

141.213.232.243/...chewing_gum.pdf

saliva salivary gum testing

shared by Nathan Goodyear on 30 Oct 12 - No Cached
  • Nathan Goodyear on 30 Oct 12
     
    Don't chew gum to increase saliva for saliva testing.
Nathan Goodyear

ScienceDirect.com - Hormones and Behavior - Salivary Testosterone Determination in Stud... - 0 views

www.sciencedirect.com/...S0018506X98914921

saliva salivary hormone hormones testosterone testing evaluation

shared by Nathan Goodyear on 30 Oct 12 - No Cached
  • Nathan Goodyear on 30 Oct 12
     
    High correlation of salivary and serum testosterone in children.  
Nathan Goodyear

High frequency of sub-optimal semen quality in an unselected population of young men - 0 views

humrep.oxfordjournals.org/...366.long

men male low sperm count quality infertility

shared by Nathan Goodyear on 29 Oct 12 - No Cached
  • Nathan Goodyear on 29 Oct 12
     
    Study found a large percentage, 40%, of young Danish men with low enough sperm count to predict infertility problems.
Nathan Goodyear

Human semen quality in the new millennium: a prospective cross-sectional popu... - 0 views

bmjopen.bmj.com/...e000990.full

men male infertility low sperm count concentration quality

shared by Nathan Goodyear on 29 Oct 12 - No Cached
  • Nathan Goodyear on 29 Oct 12
     
    2012 study that shows a slight uptick in sperm count/concentration in Danish men.  However, as the conclusion states, on 25% have optimal sperm quality.  When you look at the numbers deeper, the current general population sperm count/concentration was lower than that of men of infertile couples from 1940-1943 cohort.  Additionally, when the general population sperm count/concentration was lower than that of compared recent fertile men.
Nathan Goodyear

Oxidative stress and neurodegeneration: where are we now? - Halliwell - 2006 - Journal ... - 0 views

onlinelibrary.wiley.com/...full

oxidative damage oxidative stress detoxification CNS neurodegeneration neurodegenerative disease Free radicals Alzheimer's Parkinson's disease ALS MS

shared by Nathan Goodyear on 29 Oct 12 - No Cached
  • Nathan Goodyear on 29 Oct 12
     
    Fantastic review of oxidative damage and the CNS.  This is a 2006 review of our understanding of how neurodegeneration occurs through oxidative stress and of course poor detoxification.
Nathan Goodyear

Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in... - 0 views

ajcn.nutrition.org/...1611.full

detoxification methylation glutathione children autism oxidative stress

shared by Nathan Goodyear on 29 Oct 12 - No Cached
  • Nathan Goodyear on 29 Oct 12
     
    in this study, children with autism found to have detoxification impairment.  Particularily here, methylation disruption and glutathione depletion.
Nathan Goodyear

The Detoxification Enzyme Systems - 0 views

www.adltests.com/...etoxification_Review_Liska.pdf

detoxification detox liver kidney

shared by Nathan Goodyear on 29 Oct 12 - No Cached
  • Nathan Goodyear on 29 Oct 12
     
    Great review of phase I and II detoxification pathways and mechanisms.
Nathan Goodyear

Green Tea Reduced Inflammation, May Inhibit Prostate Cancer Tumor Growth - 0 views

www.aacr.org/...aacr-press-releases.aspx

prostate cancer inflammation NF-kapppB PSA oxidative stress damage green EGCG

shared by Nathan Goodyear on 28 Oct 12 - No Cached
  • Nathan Goodyear on 28 Oct 12
     
    Six cups of green tea daily in those men with prostate cancer found to reduce PSA, NK-KappB, and oxidative stress.  These levels were followed in men before and after surgery.
Nathan Goodyear

In U.S., Obesity Up in Nearly All Age Groups Since 2008 - 0 views

www.gallup.com/...ty-nearly-age-groups-2008.aspx

obesity obese overweight Gallup

shared by Nathan Goodyear on 28 Oct 12 - No Cached
  • Nathan Goodyear on 28 Oct 12
     
    Obesity has increased in almost every category from 2008 to present.
Nathan Goodyear

Arquivos Brasileiros de Endocrinologia & Metabologia - Estrogen receptors and function ... - 0 views

www.scielo.br/scielo.php

hormone hormones estrogen receptors estrogen receptor ER ER-alpha ER-beta men male inflammation

shared by Nathan Goodyear on 28 Oct 12 - No Cached
  • Nathan Goodyear on 28 Oct 12
     
    Good summary article on estrogen receptors in men.
Nathan Goodyear

Arthritis Research & Therapy | Abstract | Restoration of regulatory and effector T cell... - 0 views

arthritis-research.com/...abstract

lupus SLE vitamin D D3 vitamin D Th1 Th17 inflammation autoimmune disease autoimmunity arthritis

shared by Nathan Goodyear on 28 Oct 12 - No Cached
  • Nathan Goodyear on 28 Oct 12
     
    Vitamin D supplementation in those individuals with SLE found to benefit these patients.   Vitamin D found to reduce TH1 and Th17 activity.  It also was found to decrease memory B cells and auto-antibodies.  Also of note is the level of vitamin D after therapy-only at 51.4 at 2 months and 41.5 at 6 months.
Nathan Goodyear

Testosterone Concentrations In Young Pubertal And Post-Pubertal Obese Males - Mogri - C... - 0 views

onlinelibrary.wiley.com/...abstract

low T testosterone obesity overweight boys men males male

shared by Nathan Goodyear on 27 Oct 12 - No Cached
  • Nathan Goodyear on 27 Oct 12
     
    obese boys/young men between ages of 14-20 have 50% less testosterone than normal weight boys/young men.
Nathan Goodyear

Diabetology & Metabolic Syndrome | Full text | Visceral adiposity, insulin resistance a... - 0 views

www.dmsjournal.com/12

adipose tissue fat obesity cancer aromatase activity IR insulin resistance metabolic syndrome visceral

shared by Nathan Goodyear on 26 Oct 12 - No Cached
  • Nathan Goodyear on 26 Oct 12
     
    adipose tissue and it's biological activity contribution to cancer risk.  Good review of our current understanding on how adipose tissue increases the favorably of cancer.
Nathan Goodyear

Pathways of adipose tissue androgen metabolism in women: depot differences and modulati... - 0 views

ajpendo.physiology.org/...E244.full

aromatase activity fat abdominal visceral adipose tissue

shared by Nathan Goodyear on 26 Oct 12 - No Cached
  • Nathan Goodyear on 26 Oct 12
     
    aromatase activity is concentrated in subcutaneous and visceral adipose tissue.
Nathan Goodyear

Decline in semen quality among fertile men in P... [N Engl J Med. 1995] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...7816062

men decline declining sperm count number male low T testosterone infertility

shared by Nathan Goodyear on 26 Oct 12 - No Cached
  • Nathan Goodyear on 26 Oct 12
     
    Decline in concentration, function and morphological normal sperm in young men in Paris.  This was a 20 year study.  There was no reduction in semen volume.
Nathan Goodyear

Evidence for decreasing quality of semen during past 50 years. - 0 views

www.ncbi.nlm.nih.gov/...PMC1883354

sperm count low T low testosterone men male hormone hormones

shared by Nathan Goodyear on 20 Oct 12 - No Cached
  • Nathan Goodyear on 20 Oct 12
     
    sperm count and quality have decreased significantly over last 50 years.  
Nathan Goodyear

Changes in androgen receptor, estrogen receptor a... [Horm Behav. 2010] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...20223236

ER ER-alpha AR androgen receptor receptors estrogen testosterone hypothalamus hormone hormones

shared by Nathan Goodyear on 19 Oct 12 - No Cached
  • Nathan Goodyear on 19 Oct 12
     
    ER alpha and AR play role in response of hypothalamus to exogenous testosterone therapy.  It is not just the message, but how the message is interpreted.  Low T symptoms cannot be explained by "low T" alone, but how the tissue receives the message and interprets the message.
Nathan Goodyear

Upregulation of estrogen and androgen receptors modulate expression of FGF-2 and FGF-7 ... - 0 views

www.nature.com/...4500571a.html

estrogen estradiol aromatase ER-alpha prostate BPH receptor receptors hormone hormones

shared by Nathan Goodyear on 19 Oct 12 - No Cached
  • Nathan Goodyear on 19 Oct 12
     
    difficult, technical read...but take home is that ER alpha expression is increased in the male prostrate stromal cells in response to elevated estradiol levels.  Remember, that ER alpha promotes inflammation and growth.  Thus, in part, this helps to explain BPH.
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