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Nathan Goodyear

Testosterone replacement therapy improves i... [Eur J Endocrinol. 2006] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...16728551

low T low Testosterone low T men male hormone hormones Testosterone diabetes hypogonadism visceral fat cholesterol replacement therapy

shared by Nathan Goodyear on 07 Aug 14 - No Cached
  • Nathan Goodyear on 07 Aug 14
     
    In obese men with low T and type 2 diabetes, Testosterone replacement improves insulin sensitivity.  Glycated hemoglobin was also improved.  In this study group, a decrease in visceral adiposity and TC was seen.
Nathan Goodyear

Lower sex hormone-binding globulin is more strongly associated with metabolic syndrome ... - 0 views

eje-online.org/...785.long

metabolic syndrome SHBG low T Testosterone low T low Testosteorne men male hormone hormones health

shared by Nathan Goodyear on 07 Aug 14 - No Cached
  • Nathan Goodyear on 07 Aug 14
     
    low SHBG found to be more associated with metabolic syndrome in older men than low Testosterone.  The study consisted of 2502 men older than 70.  The authors proposed this occurs through the relationship between SHBG and insulin sensitivity.  I think that is a little too simplistic.
Nathan Goodyear

Inverse association between serum insulin and sex hormone-binding globulin in a populat... - 0 views

www.endocrineconnections.com/...18.full

SHBG insulin hormone hormones diabetes

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  • Nathan Goodyear on 07 Aug 14
     
    Low SHBG associated with elevated insulin levels. This was found in both sexes.  Low SHBG associated with type II Diabetes, but Increased SHBG found to be associated with Type I Diabetes.
Nathan Goodyear

Associations between sex hormone binding globulin and metabolic syndrome parameters in ... - 0 views

www.indianjmedsci.org/article.asp

SHGB metabolic syndrome hormone hormones female women obesity premenopause pre-menopausal premenopausal

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  • Nathan Goodyear on 07 Aug 14
     
    Low SHGB associated with increased association with metabolic syndrome components.  Low SHBG particuraliy associated with increased obesity (visceral) and glucose dysmetabolism. This study looked at premenopausal women.
Nathan Goodyear

A new era of testosterone and prostate cancer: from... [Eur Urol. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24011426

Testosterone prostate cancer men male hormone hormones

shared by Nathan Goodyear on 06 Aug 14 - No Cached
  • Nathan Goodyear on 06 Aug 14
     
    The tide is beginning to shift on testosterone and Prostate Cancer.  A literature review finds no support for Testosterone and Prostate carcinogenesis or low Testosterone providing any protection against prostate cancer.  
  • Blu Electronic Cigarettes on 07 Aug 14
     
    a good read!
Nathan Goodyear

PLOS ONE: Testosterone, Sex Hormone-Binding Globulin and the Metabolic Syndrome in Men:... - 0 views

www.plosone.org/...10.1371%2Fjournal.pone.0100409

metabolic syndrome Total Testosterone Total Testosterone free free Testosterone SHBG BMI obese overweight men male hormone hormones

shared by Nathan Goodyear on 06 Aug 14 - No Cached
  • Nathan Goodyear on 06 Aug 14
     
    Association of low TT, SHBG, and free Testosterone with MetS was found in this study on men.  The association was influenced by BMI i.e. the overweight were found to have a higher association than the normal BMI.
Nathan Goodyear

Both total testosterone and sex hormone-binding globulin are independent risk factors f... - 0 views

onlinelibrary.wiley.com/...abstract

metabolic syndrome men male hormone hormones Total Testosterone free bioavailable SHBG low T low Testosterone

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  • Nathan Goodyear on 06 Aug 14
     
    Study of 2361 Chinese men found that men with MetS had lower TT, bioavailable Testosterone, free Testosterone and SHBG than those men without MetS.  Additionally, Total Testosterone and SHBG were both inversely associated with the risk of MetS.  This inverse association stood for both after adjusting for the other.
Nathan Goodyear

http://care.diabetesjournals.org/content/33/7/1618.full.pdf - 0 views

care.diabetesjournals.org/...1618.full.pdf

metabolic syndrome low T Testosterone low T low Testosterone SHBG men male hormone hormones

shared by Nathan Goodyear on 06 Aug 14 - No Cached
  • Nathan Goodyear on 06 Aug 14
     
    Men with low T and low SHBG have a significantly elevated risk of metabolic syndrome.  Other studies have actually shown that low SHBG is more associated and that TT is more than free Testosterone.
Nathan Goodyear

Long-term stability of salivary cort... [Scand J Clin Lab Invest. 2005] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...16081365

saliva salivary hormone hormones

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  • Nathan Goodyear on 06 Aug 14
     
    Salivary cortisol samples shown to be stable for long length of time.
Nathan Goodyear

Measurement of steroid hormones in s... [Scand J Clin Lab Invest. 2013] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24033227

saliva salivary hormone testing hormones measurement

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  • Nathan Goodyear on 06 Aug 14
     
    Study deals with the storage temp of salivary hormone samples.
Nathan Goodyear

Estradiol concentrations and workin... [Psychoneuroendocrinology. 2013] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24011502

Estradiol E2 cognition hormone hormones women memory

shared by Nathan Goodyear on 06 Aug 14 - No Cached
  • Nathan Goodyear on 06 Aug 14
     
    women with high E2 versus low E2 had better cognitive function.
Nathan Goodyear

Lipoprotein(a) as a cardiovascular risk factor: current status - 0 views

eurheartj.oxfordjournals.org/...2844.full

cardiovascular risk disease lipoprotein a Lp(a) LDL lipoprotein(a) niacin

shared by Nathan Goodyear on 06 Aug 14 - No Cached
  • Lipoprotein(a) is a plasma lipoprotein consisting of a cholesterol-rich LDL particle with one molecule of apolipoprotein B100 and an additional protein, apolipoprotein(a)
  • Elevated Lp(a) levels can potentially increase the risk of CVD (i) via prothrombotic/anti-fibrinolytic effects as apolipoprotein(a) possesses structural homology with plasminogen and plasmin but has no fibrinolytic activity and (ii) via accelerated atherogenesis as a result of intimal deposition of Lp(a) cholesterol, or both
  • evidence suggests that apolipoprotein(a) adducts extracellularly and covalently to apolipoprotein B100-containing lipoproteins, predominantly LDL
  • ...2 more annotations...
  • Lp(a) is relatively refractory to both lifestyle and drug intervention.
  • Other agents reported to decrease Lp(a) to a minor degree (<10%) include aspirin, l-carnitine, ascorbic acid combined with l-lysine, calcium antagonists, angiotensin-converting enzyme inhibitors, androgens, oestrogen, and its replacements (e.g. tibolone), anti-estrogens (e.g. tamoxifen), and thyroxine replacement in hypothyroid subjects
  • Nathan Goodyear on 06 Aug 14
     
    full article on the previously posted abstract on Lp(a).  
Nathan Goodyear

Lipoprotein(a) as a cardiovascular risk factor: ... [Eur Heart J. 2010] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...20965889

Lp(a) lipoprotein a cardiovascular risk disease CVD

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  • Nathan Goodyear on 06 Aug 14
     
    Lp(a) is a useful biomarker in the overall assessment of those at moderate to high risk of CVD.
Nathan Goodyear

Low Sex-Hormone Binding Globulin is Associated with the Metabolic Syndrome in Postmenop... - 0 views

www.ncbi.nlm.nih.gov/...PMC1633722

metabolic syndrome MetS SHBG post-menopause post menopause menopause Testosterone free androgen index women female hormone hormones

shared by Nathan Goodyear on 05 Aug 14 - No Cached
  • Nathan Goodyear on 05 Aug 14
     
    low SHBG in post-menopausal women correlates with increased risk of metabolic syndrome.  More than that, there is an inverse correlation with SHBG in women and metabolic syndrome components.  Also, Increasing components of MetS was correlated with Testosterone and free androgen index.
Nathan Goodyear

Hyperandrogenism sensitizes mononuclear cells to promote glucose-induced inflammation i... - 0 views

www.ncbi.nlm.nih.gov/...PMC3287360

inflammation glucose PCOS Testosterone DHEA women female hormone hormones

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  • Nathan Goodyear on 05 Aug 14
     
    Interesting study finds hyperandrogenism stimulates excessive inflammatory response to glucose intake.  This study was done in otherwise healthy women not in women with PCOS.  The inflammatory cytokine production was via NF-KappaB activation.  Again, this has negative implications in women being doped with Testosterone.
Nathan Goodyear

Inflammation in Polycystic Ovary Syndrome: Underpinning of insulin resistance and ovari... - 0 views

www.ncbi.nlm.nih.gov/...PMC3309040

PCOS polycystic ovarian syndrome polycystic ovary syndrome insulin resistance inflammation androgens Testosterone women female hormone hormones

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  • Nathan Goodyear on 05 Aug 14
     
    Study points to inflammation causing hyperandrogenism via ovarian theca stimulation.
Nathan Goodyear

Hyperandrogenism induces a proinflam... [J Clin Endocrinol Metab. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24512496

androgens polycystic ovarian syndrome Testosterone DHEA androstenedione women inflammation TNF-alpha PCOS

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  • Nathan Goodyear on 05 Aug 14
     
    Very insightful study.  Study looked at hyperadrogenism and inflammation in women on the orders of PCOS.  The study subjects did not have PCOS, but hyperandrogenism via 130 mg DHEA was associated with an increase in TNF-alpha in these lean o/w healthy women.  We know this is due to hyperandrogenism as elevated Testosterone, DHEA, and androstenedione were documented with treatment. Take home:  androgens promote inflammation in women.  I believe this has serious negative implications about the massive Testosterone doping that is occurring in women today.
Nathan Goodyear

Androgens and cardiac diseases. [Monaldi Arch Chest Dis. 2013] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...25087292

CVD cardiovascular disease low T Testosterone hypogonadism men male hormone hormones

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  • Nathan Goodyear on 05 Aug 14
     
    Abstract only available here.  Take home: individuals at risk for CVD should have T levels evaluated.
Nathan Goodyear

Testosterone in Men with Advanced Li... [J Gastroenterol Hepatol. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...25087838

Testosterone men male hormone hormones cirrhosis liver disease

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  • Nathan Goodyear on 05 Aug 14
     
    published ahead of print.  The authors conclude that the Testosterone therapy in hypogonadal men with cirrhosis requires further study.  They, the authors, state that the risk of Testosterone and hepatocellular carcinoma is overstated.  This risk is associated with oral Testosterone replacement and thus in that light is not overstated.  The majority of treatment strategies today employ none oral routes of administration which would support their statement.
Nathan Goodyear

Probiotics and gut health: A special focus on liver diseases - 0 views

www.ncbi.nlm.nih.gov/...PMC2811790

probiotic probiotics liver cancer disease IBD IBS cirrhosis NAFLD gut health

shared by Nathan Goodyear on 05 Aug 14 - No Cached
  • Nathan Goodyear on 05 Aug 14
     
    Probiotics are not just for disease prevention, but also can be utilized as adjuncts for different liver disease states.  This review article highlights probiotics in IBD, IBS, surgery, NAFLD, cancer, and cirrhosis.
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