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Nathan Goodyear

Low S-adenosylmethionine concentrations fo... [Clin Chem Lab Med. 2004] - PubMed - NCBI - 0 views

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    SAMe found to be low in those with Crohn's and Ulcerative colitis disease.  Is IBD a methylation disease?  Is IBD a detoxification deficiency state due to lack of methylation?
Nathan Goodyear

The use of fecal calprotectin and la... [Acta Gastroenterol Belg. 2013] - PubMed - NCBI - 0 views

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    Useful biomarkers: calprotectin and lactoferrin used to follow GI inflammation.  Calprotectin is useful to follow inactive/active IBD.  It also has been show to predict recurrence and can aid in differentiation between IBD and IBS.  Lactoferrin appears to be a biomarker more useful in GI inflammation.
Nathan Goodyear

American Journal of Gastroenterology - Abstract of article: Diagnostic Precision of Fec... - 0 views

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    Fecal calprotectin is found to be a much better screening test for IBD than colorectal cancer.  Though, fecal Calprotectin levels were found to be elevated in colorectal cancer compared to controls, the sensitivity and specificity was low.  In contrast, a fecal Calprotectin > 100 mg/g, in this study, was found to be specific and sensitive for IBD and excluding IBS.
Nathan Goodyear

Nutritional protective mechanisms against gut inflammation - 0 views

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    Nice review of inflammation originating from the gut.  This article nicely points out the pathway involving PPAR gamma and its anti-inflammatory effects in gut inflammatory conditions such as IBD. This article also specifically discusses natural compounds that activate PPAR gamma and thus reduce inflammation.  Good deep biochemical discussion of how natural therapies reduce inflammation.  
Nathan Goodyear

Antioxidant effects of herbal therapies used by patients with inflammatory bowel diseas... - 0 views

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    slipper elm as well as other herbs found to reduce inflammation in IBD.
Nathan Goodyear

saccharomyces cerevisiae and ulcerative colitis - Google Scholar - 0 views

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    Saccharomyces cerevisiae and IBD.
Nathan Goodyear

Curcumin inhibits VEGF-mediated angiogenesis in hu... [Gut. 2008] - PubMed result - 0 views

  • Moreover, curcumin inhibits microvascular endothelial cell angiogenesis through inhibition of COX-2 expression and PGE(2) production, suggesting that this natural product possesses antiangiogenic properties, which warrants further investigation as adjuvant treatment of IBD and cancer.
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    Curcumin reduces inflammation in IBD and Cancer
Nathan Goodyear

Fecal calprotectin is a surrogate marker f... [Inflamm Bowel Dis. 2012] - PubMed - NCBI - 0 views

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    Calprotectin useful as biomarker to follow remission/active IBD disease.  
Nathan Goodyear

Questions and answers on the role of faecal calprotectin as a biological marker in infl... - 0 views

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    Calprotectin is a useful biomarker in IBD.  Colorectal cancer and GI infection can also increase fecal Calprotectin. 
Nathan Goodyear

Fecal Calprotectin: Validation as a Noninvasive Measure of B... : Journal of Pediatric ... - 0 views

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    fecal Calprotectin validated in the measure of IBD in children.
Nathan Goodyear

Probiotics and gut health: A special focus on liver diseases - 0 views

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    Probiotics are not just for disease prevention, but also can be utilized as adjuncts for different liver disease states.  This review article highlights probiotics in IBD, IBS, surgery, NAFLD, cancer, and cirrhosis.
Nathan Goodyear

Induction of clinical response and remission of inflammatory bowel disease by use of he... - 0 views

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    Study of natural therapies against UC are limited, but this review found statistical benefit in patients with IBD.  No induction of remission was seen.
Nathan Goodyear

Advances in treatment of ulcerative colitis with herbs: From bench to bedside - 0 views

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    additional reviews of natural therapies and IBD.
Nathan Goodyear

Novel role of the vitamin D receptor in maintainin... [Am J Physiol Gastrointest Liver ... - 0 views

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    Vitamin D deficiency increases risk of IBD
Nathan Goodyear

SMW - Swiss Medical Weekly - 22481443 - 0 views

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    Calprotectin is useful marker to follow inflammation in those with IBD.  Less invasive and can be used as a marker to follow recurrence.  Calprotectin is a neutrophil protein.
Nathan Goodyear

VSL#3 probiotic-mixture induces remission... [Am J Gastroenterol. 2005] - PubMed - NCBI - 0 views

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    high dose probiotic shown to provide significant benefit, even remission in those with mild/moderate ulcerative colitis.
Nathan Goodyear

Potential Therapeutic Effects of Curcumin, the Anti-inflammatory Agent, Against Neurode... - 0 views

  • The starting dose was 500 mg/day and if no toxicity was noted, the dose was then escalated to another level in the order of 1,000, 2,000, 4,000, 8,000, and 12,000 mg/day. There was no treatment-related toxicity up to 8 g/day but the bulky volume of the drug was unacceptable to the patients beyond 8 g/day.
  • The serum concentration of curcumin usually peaked at 1 to 2 hours after oral intake of curcumin and gradually declined within 12 hours
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    Great article on the benefits of curcumin in therapy for inflammation and disease.
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Nathan Goodyear

Acetyl-11-keto-beta-boswellic acid, a constituent of a herbal medicine from Boswellia s... - 0 views

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    animal study finds Boswellia reduces inflammation in Inflammatory Bowel Disease.
Nathan Goodyear

Limited effects of dietary curcumin on Th-1 driven colitis in IL-10 deficient mice sugg... - 0 views

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    curcumin shown to inhibit NF-kappaB through a IL-10 dependent pathway.  IL-10 is required and curcumin appears to augment the inhibition of NF-kappaB
Nathan Goodyear

Intestinal Lymphocyte Populations in Children with Regressive Autism: Evidence for Exte... - 0 views

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    inflammatory changes in the intestines of children with regression autism found that is different from others with inflammatory bowel diseases.
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