Dr. Goodyear

Increasing uric acid levels, even in the normal range, are associated with increased incidence of metabolic syndrome. This was found more prevalent in women, but positive correlations were seen in both sexes.

Think of PCOS as early Metabolic Syndrome.  Both increase risk of the same metabolic dysfunctions.

IV vitamin C shown to reduce EBV EA IgG and EBV VCA IgM using 7.5 grams to 50 gram infusions.  This protocol found that Magnesium reduced discomfort with the IVC therapy.

So help me out here:  If IV vitamin C has been shown to prolong time to cancer relapse, aid in reducing tumor size, improve survival with chemotherapy, improve quality of life, improve physical function, reduce chemo side effects, improve energy, reduce nausea, aid insomnia, reduce constipation, and improve depression in cancer patient--then why does the author say that IV vitamin C is contentious?  Add that IV vitamin C has not been implicated in any deaths in cancer therapy.  Contrast that with chemotherapy.  Why again is this contentious?  Whom is best served by this being contentious?

Not only is inflammation a key in carcinogenesis, but cancer plays a role in progression and prognosis.

Elevated inflammation is a poor prognostic indicator for cancer survival.

low sensitivity CRP associated with increased short-term and long-term mortality in hospitalized patients.  Also associated with a 28 fold increase in cancer mortality.

old study finds oral vitamin C destroyed substantial amount of B12.  This is the reason vitamin B 12 is given when vitamin C is given.

IV vitamin C induces cell death of prostate cancer cell lines via H2O2, which is not new, but what is new is the ascorbate-insensitive cell line.

Good discussion of the mechanism of action of IV vitamin C in cancer therapy.

IV vitamin C improves anemia.  The only possible contribution of IV vitamin C and anemia is a G6PD deficiency.

IV vitamin C aids refractory anemia.

High dose IV vitamin C shown to be well tolerated in those on hemodialysis.  Liver enzymes were followed throughout the course of the 6 month trial.  In fact, IV vitamin C was shown to improve the response of the EPO therapy.

Old case study of IV vitamin C, not high dose, used to treat acute case of hepatitis C.

IV vitamin C and IV vitamin C only can deliver levels to tumor cells that induce formation of H2O2 that then induces cell death.

study finds HT reduced Lp(a) in women and reduced the Lp(a) association with CVD.  Women not on HT in this study had higher Lp(a) versus those on HT.

Coronary artery calcium is positively associated with CAD risk.  It compares to multiple biomarker assessment, BNP, and homocysteine assessment.

Lp(a) is a distinct lipoprotein from from LDL.  An Lp(a) is a distinct cardiovascular  biomarker risk.

Lp(a) found to highly correlate with obstructive coronary disease.

Lp(a), especially the particle #, is highly associated with increased cardiovascular risk.