Study doesn't find alot of "good" evidence to support Chinese herbal medicine in BPH. However, the author states: "Before the introduction of conventional medication and surgery to China, the Chinese had solely relied on CHM to treat BPH for more than three thousand years". That is 3,000 years of observational data that is being tossed out the window.
In conclusion, dietary or environmental factors, and not a diminution of 5α-reductase, appear to be responsible for differences in androgen metabolism between Caucasians living in the United States and Chinese living in China. Powerful conclusion that environmental factors play a major role in the difference in Testosterone function between caucasian men in Western countries vs. Chinese men in Eastern countries
lower 25(OH)D level was significantly associated with lower total T, E2, SHBG, LH and FSH levels after adjusting for age, residence area, economic status and current smoker
association between 25(OH)D status and hypogonadism in Chinese men and confirms that this relationship is present in a large population
The Liaoning aircraft carrier has reached Hainan military base and we will continue to monitor its progress," a senior Taiwanese military official told Reuters on condition of anonymity
green tea not shown improve weight loss in obese chinese women with PCOS. Study doesn't identify the type of green tea. There are many types and qualities of green teas.
Study was undertaken in China due to alarming increase in breast cancer in Chinese women. This meta-analysis of 36 articles found a 44% increase in breast cancer with one abortion. This increased to 76% at 2 and 89% at 3 abortions respectively.
This study is very important and previous criticisms of prior studies linking abortion to breast cancer has been reporting bias. In China, due to the one child policy, abortion is a way of life and there is no cultural shame involved.
I am a kidney failure patient with only 25% of kidney function. Is it too late for me to take Micr-Chinese Medicine Osmotherapy ? In fact, as long as you still have urine, you can take this kind of medicine, it can help to improve your kidney function gradually.
My mother-in-law is a PKD patient with high creatinine, I want to know why PKD can cause so many symptoms ? And how to treat it? Is it really that Chinese medicine can treat it well for PKD patients?
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Article is published in Chinese, so abstract is only available. Oxytocin has antagonistic effects peripherally versus centrally. But, oxytocin appears to play role in ejaculation, detumescence and refractory phase in men.
As the rates of obesity in women in China increases, the risk of breast cancer also rises. This meta-analysis found a 7.7% increased risk of breast cancer among Chinese women that were overweight or obese.
modest statistically significant inverse associations for total and calculated free testosterone, and modest positive associations for total and calculated free estradiol with CRP concentration
Estradiol concentrations were also weakly positively associated with WBC count
An association between testosterone and WBC count was not observed
These findings are consistent with the hypothesis that in men higher androgen concentration is anti-inflammatory, and higher estrogen concentration is pro-inflammatory.
the probability of elevated CRP concentrations (≥ 3 mg/L) decreased with higher total and calculated free testosterone concentrations, while the probability increased with higher total and calculated free estradiol concentrations
there is ample evidence supporting the immunosuppressive effect of androgens
The incidence of autoimmune diseases is higher in androgen-deficient men
Studies have shown that the induction of hypogonadism in older men is followed by a significant increase in IL-6 concentrations (Khosla et al. 2002), a potent stimulator of inflammation, and that activation of the androgen receptor exerts a direct anti-inflammatory effect
It has been suggested that the mechanisms for the immunosuppressive effect of androgens could be either a direct effect on the expression of inflammatory genes (Bellido et al. 1995; Asirvatham et al. 2006), or an indirect effect through inhibition of nuclear factor-kB activation
Estradiol is the major biologically active estrogen, and about 80% is formed in adult men from the aromatization of testosterone primarily in the adipose tissue
estrogen can stimulate the transcription factor C/EBP-β, which is involved in CRP transcription
Most prior cross-sectional studies have observed inverse associations between androgen concentrations and inflammatory biomarkers
A recent study in Chinese men showed that lower concentrations of total and calculated free testosterone were associated with higher CRP concentration
Data from the Boston Area Community Health Survey also reported inverse associations between testosterone and CRP concentrations
Total testosterone was inversely associated with WBC count (Tang et al. 2007; Schneider et al. 2009; Brand et al. 2012), but calculated free testosterone was not associated with WBC
The first trial found a decrease in CRP, interleukin-1β (IL-1β), and tumor necrosis factor-α (TNFα) but no changes in IL-6 and IL-10 concentrations between the active treatment and placebo arms
the majority of studies in the literature have not observed statistically significant associations between estradiol and inflammatory biomarkers in men, although several of them observed point estimates in the positive direction
total testosterone and estradiol compete for binding to SHBG, and seem to have opposite effects on the concentration of inflammatory biomarkers
A small randomized controlled trial of estrogen replacement therapy in prostate cancer patients showed an increase in CRP in the active treatment group versus the comparator group
Obese men are known to have lower androgen concentrations compared to their normal-weight counterparts
The strongest suggestion of an interaction was the inverse association between androstanediol glucuronide and CRP concentrations in obese participants, while the association was positive in the non-obese
A recent Chinese cross-sectional study observed stronger inverse associations between total testosterone and CRP concentrations in individuals with a BMI of 27.5 kg/m2 or greater
our results suggest that total and calculated free testosterone are modestly inversely associated with CRP concentrations, and that total and calculated free estradiol are modestly positively associated with CRP and WBC
Study results suggest that higher Testosterone and lower Estrogen levels provide anti-inflammatory effects in men. The inflammatory biomarker assessed here was CRP. Low total and calculated free Testosterone was associated with an increase in CRP. In contrast, total and free Estrogen was associated with an increase in CRP. Estradiol increased WBC count and SHBG was inversely related to WBC count in this study.