Only abstract available here, but this article furthers the Reverse Warburg effect.  The authors here describe it as metabolic symbiosis.

Elevated beta-glucoronidase associated with 1.7 x increased risk of colon cancer.

Vitamin D again implicated in cancer.  This time prostate cancer.  Study found that vitamin D regulates the expression of GDF-15 which inhibits NF-kappaB.  Low vitamin D leads to decreased GDF-15 expression which leads to increased NF-kappaB transcription and resultant inflammation.

prebiotics

Good biochemical review of the Reverse Warburg Effect.  In pdf format, so I can't highlight.

A good discussion of what is proposed the Reverse Warburg effect.  A process by which the local environment dictates tumor progression.  The cancer cells release ROS primarily in the form of H2O2 and this leads to Cancer Associated Fibroblasts (CAFs) in the stroma.  The altered stromal environment increases ROS further and promotes ocogenic metabolites through the classic Warburg effect.  This high lactate production from the CAFs then is used by the cancer cells via classic oxidative phosphorylation.  Complex, beautiful and still an the understanding is a work in progress.   This study/article points to the importance of oxidative stress in some cancer development through CAFs.

Really fascinating article on tumor signaling. The article points to a complex signaling between cancer cells and stromal fibroblasts that results in myofibroblast transformation that increases the microenvironment favorability of cancer. This article points to oxidative stress as the primary driving force.  

Abstract only available in this link--loss of glutathione results in decreased mitochondria.  This has significant disease implications.

Cholesterol lowering drug, atorvastatin, lowers androgen levels in women with PCOS.  The same has been shown in men.

Case report links possible methylphenidate, Ritalin, use to Testicular failure. 

This study finds a strong correlation between advancing breast cancer, decreased catalase and SOD with increasing MDA.  The authors of this study conclude this is a key factor in carcinogenesis and not a by-product of cancer.  This flies in the face of traditional medicines fear of antioxidant therapy in cancer.

Study finds a reduction in SuperOxide Dismutase and Glutathione Perioxidase in advancing breast cancer.  Cancer is a high oxidative stress disease that results in inflammation, mitochondrial dysfunction and proliferation.  Adenosine Deaminase (ADA) is proposed to be another biomarker to assess tumor stage.  

Selenium is a "U" shaped curve.  Abstract only available here.

Selenium is very important in thyroid function, not just Iodine.  Low Se levels significantly correlate with thyroid cancer.

Selenium deficiency has important implications in disease: including CVD, GI cancer, prostate cancer, and diabetes.

Urinary Selenium is a good marker of dietary Se intake.

Urinary excretion of selenium proved to be a good marker of dietary Se intake in Japanese study.

Selenium deficiencies, selenosis, lead to disease.

Selenium (Se) deficiency is associated with increased oxidative stress.  Selenium is a cofactor necessary for glutathione perioxidase.  Selenium reduced 8-OHdG, promoted cell growth inhibition and cell death pointing to significant Cancer implications.

Anything and everything one would want to know regarding thyroid hormone signaling.  Doctors, especially endocrinologists, need to read this.  T4 is not or is ever inside target cells.  The enzymes, deiodinase types 1, 2, and 3, are what control the thyroid hormone at the cellular levels.  Deiodinase-2 is what generates T3 in the cytosol of the cell.  In contrast, deiodinase-3 is what generates rT3 which is inactive.  High Fat diet increases deiodinase-3.