marked reversal of systemic degenerative phenotypes in adult mice observed here support the development of regenerative strategies designed to restore telomere integrity.
These findings support the hypothesis that ovarian hyperandrogenism associated with luteal insufficiency increases the risk of BC in premenopausal women.
We found inverse associations between breast cancer-risk and n-3 fatty acid levels in breast adipose tissue
In conclusion, our data based on fatty acids levels in breast adipose tissue suggest a protective effect of n-3 fatty acids on breast cancer risk and support the hypothesis that the balance between n-3 and n-6 fatty acids plays a role in breast cancer
After adjustment for biomarkers of seafood intake, total urine arsenic was associated with increased prevalence of type 2
diabetes. This finding supports the hypothesis that low levels of exposure to inorganic arsenic in drinking water, a widespread
exposure worldwide, may play a role in diabetes prevalence
hese data support the hypothesis that androgen treatment increases
nocturnal and spontaneous erections, and sexual interest, and has some
capacity to improve mood.
significant weight loss (and leptin reduction) (P < 0.01) was recorded in the myo-inositol group, whereas the placebo group actually increased weight
hese data support a beneficial effect of myo-inositol in women with oligomenorrhea and polycystic ovaries in improving ovarian function.
researchers showed how estrogen receptors located in the hypothalamus serve as a master switch to control food intake, energy expenditure and body fat distribution.
This research seems to support a link between estrogen and regulation of obesity
ventromedial nucleus or VMN, is a key center for energy regulation.
When estrogen levels in the VMN dipped, the animals' metabolic rate and energy levels also plummeted
The findings suggested that the ER-alpha in this region plays an essential role in controlling energy balance, body fat distribution and normal body weight.
The metabolism of DCI is associated with insulin sensitivity and resistance, supporting the concept that second messengers have a role in responses to and resistance to insulin.
these results support the concept that intestinal bacteria induce endogenous signals that play a pathogenic role in hepatic insulin resistance and NAFLD and suggest novel therapies for these common conditions.
These results support the notion that occupational lead exposure at currently acceptable levels has a small adverse effect on sperm quality, especially sperm motility, and that this effect is at least partially reversible
These studies show that one third to two thirds of dieters regain more weight than they lost on their diets, and these studies likely underestimate the extent to which dieting is counterproductive because of several methodological problems,
there is little support for the notion that diets lead to lasting weight loss or health benefits.