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harshitatyagi

What Is Secondary Infertility? Causes and Effects - 0 views

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    Secondary infertility is the inability to conceive or complete a pregnancy after a previous birth. To be classified as secondary infertility, a previous birth must have occurred without the help of drugs or fertility treatments such as IVF. If you've been trying to get pregnant for a while without success, you may be wondering if something is wrong. Is secondary infertility possible? To know the common sign of Secondary Infertility click on the link.
Nathan Goodyear

The development of mitochondrial medicine - 0 views

  • n addition to being a primary cause of disease, mitochondrial DNA mutations and impaired oxidation have now been found to occur as secondary phenomena in aging as well as in age-related degenerative diseases such as Parkinson, Alzheimer, and Huntington diseases, amyotrophic lateral sclerosis and cardiomyopathies, atherosclerosis, and diabetes mellitus.
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    good discussion on primary and secondary mitochondrial diseases.  Aging and age-related disease are the result of secondary mitochondrial dysfunction
Nathan Goodyear

Sudden cardiac death secondary to antidepressant and antipsychotic drugs - 0 views

  • Sudden cardiac death secondary to antidepressant and antipsychotic drugs
  • This review examines the mechanisms and predisposing factors underlying the development of cardiac arrhythmias, and sudden cardiac death, associated with antidepressant and antipsychotic drugs in clinical use.
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    Sudden cardiac death secondary to antidepressant and antipsychotic drugs
Nathan Goodyear

Characteristics of Secondary, Primary, and Compensated Hypogonadism in Aging Men: Evide... - 0 views

  • Circulating testosterone (T) in men declines progressively by 0.4–2% per year from the third decade onward
  • late-onset hypogonadism (LOH) (6, 7), whereas others have used various terms including andropause, male menopause, and androgen deficiency syndrome of the aging male.
    • Nathan Goodyear
       
      all names for Low T--interesting
  • Secondary hypogonadism is associated with obesity (and potentially reversible) independently of age
  • ...2 more annotations...
  • primary hypogonadism (probably the genuine form of LOH) is strongly associated with age
  • Compensated hypogonadism represents a distinct clinical entity that warrants continued monitoring to prevent or preempt further deterioration
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    Study divides low T into primary (age), secondary (weight), and compensated hypogonadism (elevated LH with normal T)
Nathan Goodyear

Therapy-Related Secondary Cancers - Holland-Frei Cancer Medicine - 0 views

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    Chemotherapy and radiation therapy increase risk of secondary cancers.
Nathan Goodyear

Low testosterone in a male adolescen... [J Paediatr Child Health. 2014] - PubMed - NCBI - 0 views

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    case study of secondary hypogonadism resulting from anabolic steroid use.
Nathan Goodyear

Secondary Adrenal Insufficiency: An Overlooked Cause of Hyponatremia - 0 views

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    Good case review of secondary adrenal insufficiency.  A common cause of low sodium and needs to be considered in elderly patients.  Also, low cortisol is associated with increased ADH.  In the case of adrenal insufficiency, the negative feed back of cortisol to the HPA is lost and recreation of CRH, which is an ADH secretagogue, will increase ADH secretion.
harshitatyagi

When should IVF be done? - 0 views

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    The most generic question that interrupts every couple's mind is when the IVF process should be done. Is it done when one fails to conceive, or is it done when one suffers from secondary infertility.
Nathan Goodyear

Bisphenol-A acts as a potent estrogen vi... [Mol Cell Endocrinol. 2012] - PubMed - NCBI - 0 views

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    Bisphenol A acts via non-classical genomic signaling and more through weaker non-classical membrane receptors and their secondary messengers.
Nathan Goodyear

Inhibitory effect of S-adenosylmethionine on the growth of human gastric cancer cells i... - 0 views

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    SAMe show a decrease in gastric cell growth in vitro and in vivo studies. This appears to be secondary to the resolved hypomethylation status of the c-myc and the uPA genes.
Nathan Goodyear

D-chiro-inositol metabolism in diabetes mellitus - 0 views

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    d-chiro-inositol levels shown to be low in diabetics.  Thus, d-chiro-inositol would prove to be helpful in diabetes management.  D-chiro-inositol is a secondary messenger in insulin signaling
Nathan Goodyear

Controlled trial of N-acetylcysteine for patients with probable Alzheimer's disease - 0 views

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    NAC shown to improve secondary measures of cognitive function in small study in those with Alzheimer's disease. NAC proves to be a reliable means to reduce free radical induced advanced glycation end productions and resultant inflammation. Also was shown to be well tolerated.
Nathan Goodyear

Characteristics of Secondary, Primary, and Compensated Hypogonadism in Aging Men: Evide... - 0 views

  • Older men were more likely to have primary [relative risk ratio (RRR) = 3.04; P < 0.001] and compensated (RRR = 2.41; P < 0.001) hypogonadism. Body mass index of 30 kg/m2 or higher was associated with secondary hypogonadism (RRR = 8.74; P < 0.001)
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    The prevalence of low T varies significantly between lean versus overweight men.  This suggests a significant contribution of obesity and its biologic effects as a cause of low T.  The difference is 30%.
Nathan Goodyear

Androgen Deprivation Therapy, Insulin Resistance, and Cardiovascular Mortality: An Inco... - 0 views

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    Androgen deprivation therapy is associated with increased diabetes, metabolic syndrome, insulin resistance, and cardiovascular mortality.  The longer the duration of therapy, the more the progression of metabolic dysfunction.  This process seems similar to chemotherapy i.e. secondary cancer due to chemotherapy.  The treatment of one disease, prostate cancer in this case, leads to an increase in the risk of the #1 killer in men--logic seems severely flawed there.
Nathan Goodyear

Fifteen years of experience with intramuscular testosterone undecanoate for substitutio... - 0 views

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    Abstract presented finds that Testosterone IM undecanoate significantly reduced metabolic syndrome parameters in men.  This study looked at men with secondary hypogonadism and late onset.  The ages were from 15-72.  The full is not available as of this post.  The study only looked at serum T.  This limits the usefulness of this test.  According to this abstract, no evaluation of SHBG was performed.  Though not significant, PSA and prostate volume increased.
Nathan Goodyear

Male anorgasmia treated with oxytocin. [J Sex Med. 2008] - PubMed - NCBI - 0 views

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    Another limited finding of 1. Male anorgasmia, they don't disclose whether this was primary or secondary, resolved with intranasal oxytocin.  
Nathan Goodyear

Autoschizis: another cell death for canc... [Ital J Anat Embryol. 2001] - PubMed - NCBI - 0 views

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    The autoschizis from IV vitamin C and K3 proposed to be secondary to oxidative stress.
Nathan Goodyear

[Androgenic deficit and its treatment in stroke male patients with diabetes mellitus ty... - 0 views

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    Small study of 154 men post 1rst stroke finds a reduction in a second ischemic stroke with Testosterone therapy.  That equals a 7.1% risk of secondary stroke in the Testosterone treated group (diagnosed with low T) versus 16.6% in the untreated group.  Testosterone was started one week after the first stroke event.
Nathan Goodyear

Overactivation of S6 Kinase 1 as a Cause of Human Insulin Resistance During Increased A... - 0 views

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    High protein intake can lead to insulin resistance.  Glucose regulation by insulin and skeletal muscle removal of glucose is disrupted by high amino acid intake through disruption of secondary insulin signaling.
Nathan Goodyear

Age-related testosterone decline is due to waning of both testicular and hypothalamic-p... - 0 views

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    Only abstract available here, but low T is the result of primary (testicular failure) and/or secondary (HPA failure). 
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