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Nathan Goodyear

Effect of vasopressin 1b receptor blockade on the hypothalamic-pituitary-adrenal respon... - 0 views

joe.endocrinology-journals.org/...285.full.pdf

stress HPA hypothalamus pituitary axis hypothalamic-pituitary chronic CRH AVP vasopressin

shared by Nathan Goodyear on 03 Oct 12 - No Cached
  • Nathan Goodyear on 03 Oct 12
     
    repeated stress results in down regulation of central stress response ie. blunted CRH response.
Nathan Goodyear

Testosterone Suppression of CRH-stimulated Cortisol in Men - 0 views

www.ncbi.nlm.nih.gov/...PMC1470424

Testosterone cortisol HPA hormone hormones men male

shared by Nathan Goodyear on 19 Jun 15 - No Cached
  • Nathan Goodyear on 19 Jun 15
     
    Testosterone inhibits CRH and thus cortisol production in men.  This has implications in men with low T and low Cortisol.
Nathan Goodyear

Neuropsychopharmacology - Testosterone Suppression of CRH-Stimulated Cortisol in Men - 0 views

www.nature.com/...1300742a.html

Testosterone cortisol hormone hormones men male

shared by Nathan Goodyear on 19 Jun 15 - No Cached
  • Nathan Goodyear on 19 Jun 15
     
    Testosterone inhibits CRH and thus cortisol.
Nathan Goodyear

Leptin inhibition of the hypothalamic-pituitary-adrenal axis in response to stress. - P... - 0 views

www.ncbi.nlm.nih.gov/...9275075

leptin CRH HPA axis HPA hormone hormones

shared by Nathan Goodyear on 17 Jun 15 - No Cached
  • Nathan Goodyear on 17 Jun 15
     
    Leptin inhibits CRH, thus decreasing the HPA axis.
Nathan Goodyear

Secondary Adrenal Insufficiency: An Overlooked Cause of Hyponatremia - 0 views

www.ncbi.nlm.nih.gov/...PMC4330026

adrenal insufficiency hyponatraemia sodium ADH cortisol CRH ACTH

shared by Nathan Goodyear on 25 Sep 17 - No Cached
  • Nathan Goodyear on 25 Sep 17
     
    Good case review of secondary adrenal insufficiency.  A common cause of low sodium and needs to be considered in elderly patients.  Also, low cortisol is associated with increased ADH.  In the case of adrenal insufficiency, the negative feed back of cortisol to the HPA is lost and recreation of CRH, which is an ADH secretagogue, will increase ADH secretion.
Nathan Goodyear

Hypothalamo-Pituitary-Adrenal Axis Dysfunction in Chronic Fatigue Syndrome, and the Eff... - 0 views

jcem.endojournals.org/...3545.full.pdf

CFS chronic fatigue syndrome adrenal fatigue cortisol therapy

shared by Nathan Goodyear on 12 May 12 - No Cached
  • Nathan Goodyear on 12 May 12
     
    This study reveals CFS to be low adrenal cortisol output problem. In this study, low dose cortisol (hydrocortisone) therapy improved symptoms of fatigue and improved the CRH adrenal stimulation of adrenal cortisol production.
Nathan Goodyear

Hypothalamo-Pituitary-Adrenal Axis Dysfunction in Chronic Fatigue Syndrome, and the Eff... - 0 views

jcem.endojournals.org/...3545.long

CFS chronic fatigue syndrome hydrocortisone cortisol fatigue adrenal fatigue hypoadrenia HPA adrenal insufficiency adrenal adrenals

shared by Nathan Goodyear on 01 May 12 - No Cached
  • We conclude that the improvement in fatigue seen in some patients with chronic fatigue syndrome during hydrocortisone treatment is accompanied by a reversal of the blunted cortisol responses to human CRH
  • These data further suggest that the hypocortisolism found in chronic fatigue syndrome may be secondary to reduced adrenal gland output.
  • 5-mg replacement dose of hydrocortisone, and the remainder 10 mg
  • Nathan Goodyear on 01 May 12
     
    low dose hydrocortisone therapy (defined as 5-10 mg), in this study, was used to treat CFS.  This study found an improvement in symptoms in these patients.  Additionally, low cortisol was found in these patients with CFS.  Their conclusion, was that low adrenal function is a component of CFS and low dose hydrocortisone therapy is an effective treatment.   Now, is the low cortisol as the result of increased metabolism as well?
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