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Increased utilization of fructose has a positive effect on the development of breast ca... - 0 views

www.ncbi.nlm.nih.gov/...PMC5622605 fructose glucose nutrition cancer
shared by Nathan Goodyear on 22 May 19 - No Cached
  • Nathan Goodyear on 22 May 19
     
    Cancer can utilize fructose as an equal substitute for glucose in a low glucose environment. Good reason to avoid moderate to high glycemic fruits.
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Get Back To Quality Life With India's Cervical Spine Surgeons - 0 views

steemit.com/...ndia-s-cervical-spine-surgeons India's cervical spine surgeons top 10 cervical spine surgeons of India 10 cervical spine surgeons of India
shared by spineneuro on 04 Dec 21 - No Cached
  • spineneuro on 04 Dec 21
     
    India's cervical spine surgeons have experience and skills are known across the world for cervical laminoplasty surgery. Patients from all around the world do come to India because of the top 10 cervical spine surgeons of India to get dire therapeutic interest or due to higher medicinal offerings by India's cervical spine surgeons which do those surgeries at the most moderate rates. Call +91-98604-32255 or email at enquiry@spineandneurosurgeryhospitalindia.com For submitting queries and booking appointments.
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Cardiac Surgery in India Your Ultimate Solution to the Secret of Your Heart Conditions - 0 views

www.articleted.com/...ecret-of-Your-Heart-Conditions Cardiac Surgery Heart Surgeries Hospitals Cardiac Surgery India Cost Cardiac Surgery India Cardiac Surgery Cost in India Low Cost Cardiac Surgery India Best Heart Surgery Hospitals In India Top 10 Heart Surgeries Hospitals of India Top Hospitals for Cardi
shared by indian-health on 09 Dec 21 - No Cached
  • indian-health on 09 Dec 21
     
    Many global sufferers seeking to undergo #Cardiac surgical procedures and treatment choose #India due to the top-notch clinical services at moderately cheap rates.The list of #Topcardiacsurgeons of India has an unbeatable record of providing comprehensive #Cardiachealthcare across a spectrum of disciplines in medicines Read More https://www.articleted.com/article/448879/1973/Cardiac-Surgery-in-India-Your-Ultimate-Solution-to-the-Secret-of-Your-Heart-Conditions
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https://www.thefastleanpro.us/ - 0 views

www.thefastleanpro.us the fast lean pro us usa fastlean fastleanpro caps drops uk buy jar get customer benefits 2023 work scam pros ebay pro2023 drop price
shared by fitspresso on 27 Sep 23 - No Cached
  • fitspresso on 27 Sep 23
     
    Fast Lean Pro™ (official) | weight lose Formula thefastleanpro.us · by Fast Lean Pro Fast Lean Pro Only $49/Bottle Limited Time Offer! Fast Lean Pro Special Deal + Special 51% Discount Save $300 + 180 Days Money Back Guarantee FastLeanPro The #1 Solution To natural metabolism booster helps you lose weight quickly without starving yourself. Fast Lean Pro is a natural powder supplement for weight loss that has recently been developed by Japanese scientists. Regular Price: $99/per bottle Only for: $49/per bottle What Is Fast Lean Pro? Fast Lean Pro is a powdered dietary powdery supplement designed to aid in weight loss. It contains a unique combination of ingredients that are believed to activate the body's "fasting switch" to optimize results. This product focuses not only on weight loss but also on promoting cellular rejuvenation, fasting, and a healthy metabolism. The concept behind Fast Lean Pro is that incorporating fasting into one's lifestyle can lead to positive outcomes irrespective of individual food choices and eating habits. To comprehend the mechanism of the Fast Lean Pro process, it is necessary to delve into its specific details. One of the few weight loss pills on the market that contains Fibersol is Fast Lean Pro. This safe, specialized fiber adds bulk to its weight when combined with water, curbing your appetite before it throws off your meal plan. If you're trying to lose weight or curb your appetite, Fast Lean Pro can help. Supporting substances such as niacin and chromium contribute to this. The body can further benefit from these nutrients, such as through improved metabolic regulation. Fast lean Pro is non-GMO, vegan friendly, and contains no artificial ingredients or stimulants. Fast Lean Pro is a weight loss product that promotes the body's natural self-feeding process. The body naturally removes old, damaged cells through a process known as autophagy to encourage cell regeneration and repair. Recent studies by a group
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Variations in common diseases, hospital admissions, and deaths in middle-aged adults in... - 0 views

www.thelancet.com/...fulltext PURE cancer prospective urban rural epidemiology study PURE study
shared by Nathan Goodyear on 05 Sep 19 - No Cached
  • Nathan Goodyear on 05 Sep 19
     
    Latest study finds in moderate and high income countries, cancer has overtaken cardiovascular disease as the #1 killer between the ages of 35-70.
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PLOS Medicine: Leisure Time Physical Activity of Moderate to Vigorous Intensity and Mor... - 0 views

www.plosmedicine.org/...journal.pmed.1001335 exercise overweight obesity mortality
shared by Nathan Goodyear on 18 Nov 12 - No Cached
  • Nathan Goodyear on 18 Nov 12
     
    no surprise that sedentary lifestyle associated with decreased lifespan. Exercise is beneficial in normal weight and obese individuals.  Also of note, one does not need to train for a marathon to see the health benefits.  Exercise is more about intensity than it is about duration/frequency.
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A Vitamin B-12 Supplement of 500 μg/d for Eight Weeks Does Not Normalize Urin... - 0 views

jn.nutrition.org/...142.abstract vitamin B12 B12 vitamin vitamins
shared by Nathan Goodyear on 19 Feb 13 - No Cached
  • Nathan Goodyear on 19 Feb 13
     
    current vitamin B12 recommendations are too low.  Proper vitamin B12 biomarker testing reveals this fact. The problem is most people fall prey to the lack of knowledge behind simple serum levels.  Simple B12 serum levels are woefully inadequate. Insurance would rather one stay with inadequate testing to save money, rather than actually read the science to learn about new testing.
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Effect of Tongkat Ali on stress hormones and psychological mood state in moderately str... - 0 views

www.ncbi.nlm.nih.gov/...PMC3669033 Tongkat Ali long jack cortisol stress testosterone hormone hormones
shared by Nathan Goodyear on 09 Mar 15 - No Cached
  • At the age of 60, testosterone levels are typically only 40-50% of youthful levels and may be lower
  • Eurycoma contains a group of small peptides referred to as “eurypeptides” that are known to have effects in improving energy status and sex drive in studies of rodents
  • The effects of tongkat ali in restoring normal testosterone levels appears to be less due to actually “stimulating” testosterone synthesis, but rather by increasing the release rate of “free” testosterone from its binding hormone, sex-hormone-binding-globulin (SHBG)
  • ...6 more annotations...
  • The current study found that daily supplementation with tongkat ali root extract (200 mg/day) improves stress hormone profile (lower cortisol; higher testosterone) and certain mood state parameters (lower tension, anger, and confusion)
  • tongkat ali supplementation (100 mg/day) improved lean body mass, 1-RM strength, and arm circumference to a significantly greater degree compared to a placebo group.
  • In a recent 12-week trial [46] of Eurycoma longifolia supplementation (300 mg/day), men (30–55 years of age) showed significant improved compared to placebo in the Physical Functioning domain of the SF-36 quality of life survey
  • sexual libido was increased by 11%
  • In men with low testosterone levels (average age 51 years), one month of daily supplementation with tongkat ali extract (200 mg/day) resulted in a significant improvement in serum testosterone levels and quality-of-life parameters
  • rise in cortisol and drop in testosterone is an early signal of “overtraining”
  • Nathan Goodyear on 09 Mar 15
     
    Tongkat Ali, commonly known as long jack, is found to reduce stress and increase Testosterone.  Stress is one of the common causes of low T in men.  It appears that long Jack functions as an adaptogen.
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R O M Knee Brace - 0 views

www.wheelchairindia.com/...Tynor-R-O-M-Knee-Brace Functional Braces Best for: Sports injuries after surgery functional knee braces knee rehabilitation program knee injuries or knee surgery free movement of the knee joint decrease knee pain improve knee stability
shared by wheelchairindia9 on 21 Mar 16 - No Cached
  • wheelchairindia9 on 21 Mar 16
     
    PF Night Splint Compared to plantar based splints, patients prefer dorsal models because they are less bulky, cooler, lower profile and easier to walk in at night. PF Night Splint includes all of these features and more. Neoprene calf and toe straps along with gel padding on the top of the foot help reduce pressure points and the plastic-free bottom offers safer nighttime ambulation. Even added more room in the forefoot to accommodate wider feet and new flexible shell allows easier nighttime ambulation without compromising the ability to hold the foot at 90° during rest. Finally, a plantar fasciitis splint patients will wear all night! Neoprene calf. Padded foam liner. Fits right or left. Not made with natural rubber latex. PF Night Splint (Derotation) Applications Prevention and correction of foot drop. Night splint for early healing. Ambulatory, can be used as a day splint. Perfect post-operative immobilisation and derotation. Peroneal / Peritibial nerve or muscle damage. Ankle or Plantar flexion contracture and functional alignment. Can be used to protect the diabetic/ injured ankle & foot. PF Night Splint (Derotation) Features Removable de-rotation bar. Moulded foot casing, aesthetically pleasing and durable. Effective Liner, improved comfort. Highly functional Design, customized degree of dorsiflexion. Double strapping mechanism, better grip. Tynor R O M Knee Brace Prefabricated, custom adjusted R.O.M. Knee Brace controls and restrict flexion/extension of the knee joint through a multi-point joint fixation system to allow a range of motion or immobilization to the knee. Universal design allows it to be used on quite a big range of population and for a multiple orthopedic problems associated with knee joint. Immobilization at any angle Controlled motion between any two angles Quick and easy application and removal. Tynor R O M Knee Brace Features R.O.M. Dial 0 to 120 degree flexion. 0 to 60 degree hyper extention Locking at any
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Moderation of psychosocial risk factors thro... [Arthritis Rheum. 2007] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...17195240 saliva salivary cortisol arthritis pain hormone hormones
shared by Nathan Goodyear on 01 May 12 - No Cached
  • Nathan Goodyear on 01 May 12
     
    This study reveals low am cortisol and high pm cortisol associated with pain.  This study evaluated cortisol with both saliva.
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JISSN | Full text | Effect of Magnolia officinalis and Phellodendron amurense... - 0 views

www.jissn.com/37 Relora magnolia officinalis stress cortisol mood
shared by Nathan Goodyear on 06 May 14 - No Cached
  • Nathan Goodyear on 06 May 14
     
    Relora found to reduce cortisol in short study.
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Testosterone Deficiency, Cardiac Health, and Older Men - 0 views

www.hindawi.com/...143763 low T Testosterone obesity type II diabetes diabetes health wellness metabolic syndrome lipids cholesterol hypogonadism TDS testicular dysgenesis syndrome men male hormone hormones prostate cancer
shared by Nathan Goodyear on 12 May 14 - No Cached
  • Studies have shown pharmacological doses of testosterone to relax coronary arteries when injected intraluminally [39] and to produce modest but consistent improvement in exercise-induced angina and reverse associated ECG changes [40]. The mechanism of action is via blockade of calcium channels with effect of similar magnitude to nifedipine
    • Nathan Goodyear
      Nathan Goodyear on 12 May 14
       
      This directly refutes the recent studies (3) that Testosterone therapy increases cardiovascular events.
    • Nathan Goodyear
      Nathan Goodyear on 13 May 14
       
      Testosterone acts as a calcium channel blocker inducing vasodilation.
  • men with chronic stable angina pectoris, the ischaemic threshold increased after 4 weeks of TRT and a recent study demonstrates improvement continuing beyond 12 months [
  • Exercise capacity in men with chronic heart failure increased after 12 weeks
  • ...36 more annotations...
  • Studies have shown an inverse relationship between serum testosterone and fasting blood glucose and insulin levels
  • Medications such as chronic analgesics, anticonvulsants, 5ARIs, and androgen ablation therapy are associated with increased risk of testosterone deficiency and insulin resistance
  • Women with T2D or metabolic syndrome characteristically have low SHBG and high free testosterone
    • Nathan Goodyear
      Nathan Goodyear on 12 May 14
       
      This stands in polar opposite of that with men.
  • Hypogonadism is a common feature of the metabolic syndrome
  • The precise interaction between insulin resistance, visceral adiposity, and hypogonadism is, as yet, unclear but the important mechanisms are through increased aromatase production, raised leptin levels, and increase in inflammatory kinins
  • levels of testosterone are reduced in proportion to degree of obesity
  • Men should be encouraged to combine aerobic exercise with strength training. As muscle increases, glucose will be burned more efficiently and insulin levels will fall. A minimum of 30 minutes exercise three times weekly should be advised
  • Testosterone increases levels of fast-twitch muscle fibres
  • By increasing testosterone, levels of type 2 fibres increase and glucose burning improves
  • Weight loss will increase levels of testosterone
  • studies now clearly show that low testosterone leads to visceral obesity and metabolic syndrome and is also a consequence of obesity
  • In the case of MMAS [43], a baseline total testosterone of less than 10.4 nmol/L was associated with a greater than 4-fold incidence of type 2 diabetes over the next 9 years
  • There is high level evidence that TRT improves insulin resistance
  • Low testosterone predicts increased mortality and testosterone therapy improves survival in 587 men with type 2 diabetes
  • A similar retrospective US study involved 1031 men with 372 on TRT. The cumulative mortality was 21% in the untreated group versus 10% ( ) in the treated group with the greatest effect in younger men and those with type 2 diabetes
  • the presence of ED has been shown to be an independent risk factor, particularly in hypogonadal men, increasing the risk of cardiac events by over 50%
  • A recent online publication on ischaemic heart disease mortality in men concluded optimal androgen levels are a biomarker for survival
  • inverse associations between low TT or FT (Table 2) and the severity of CAD
  • A recent 10 year study from Western Australia involving 3690 men followed up from 2001–2010 concluded that TT and FT levels in the normal range were associated with decreased all-cause and cardiovascular mortality, for the first time suggesting that both low and DHT are associated with all-cause mortality and higher levels of DHT reduced cardiovascular risk
  • TDS is associated with increased cardiovascular and all-cause mortality
  • The effect of treatment with TRT reduced the mortality rate of treated cohort (8.4%) to that of the eugonadal group whereas the mortality for the untreated remained high at 19.2%
  • hypogonadal men had slightly increased triglycerides and HDL
  • Men with angiographically proven CAD (coronary artery disease) have significantly lower testosterone levels [29] compared to controls ( ) and there was a significant inverse relationship between the degree of CAD and TT (total testosterone) levels
  • TRT has also been shown to reduce fibrinogen to levels similar to fibrates
  • men treated with long acting testosterone showed highly significant reductions in TC, LDL, and triglycerides with increase in HDL, associated with significant reduction in weight, BMI, and visceral fat
  • Low androgen levels are associated with an increase in inflammatory markers
  • In the Moscow study, C-reactive protein was reduced by TRT at 30 weeks versus placebo
  • In some studies, a decline in diastolic blood pressure has been observed, after 3–9 months [24, 26] and in systolic blood pressure
  • A decline was noted in IL6 and TNF-alpha
  • No studies to date show an increase in LUTS/BPH symptoms with higher serum testosterone levels
  • TRT has been shown to upregulate PDE5 [65] and enhance the effect of PDE5Is (now an accepted therapy for both ED and LUTS), it no longer seems logical to advice avoidance of TRT in men with mild to moderate BPH.
    • Nathan Goodyear
      Nathan Goodyear on 12 May 14
       
      What about just starting with normalization of Testosterone levels first.
  • Several meta-analyses have failed to show a link between TRT and development of prostate cancer [66] but some studies have shown a tendency for more aggressive prostate cancer in men with low testosterone
    • Nathan Goodyear
      Nathan Goodyear on 12 May 14
       
      And if one would have looked at their estrogen levels, I guarantee they would have been found to be elevated.
  • low bioavailable testosterone and high SHBG were associated with a 4.9- and 3.2-fold risk of positive biopsy
  • Current EAU, ISSAM, and BSSM guidance [1, 2] is that there is “no evidence TRT is associated with increased risk of prostate cancer or activation of subclinical cancer.”
  • Men with prostate cancer, treated with androgen deprivation, develop an increase of fat mass with an altered lipid profile
  • Erectile dysfunction is an established marker for future cardiovascular risk and the major presenting symptom leading to a diagnosis of low testosterone
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Review of health risks of low testosterone and testosterone administration - 0 views

www.ncbi.nlm.nih.gov/...PMC4391003 low Testosterone low T Testosterone men male hormone hormones health
shared by Nathan Goodyear on 28 Apr 15 - No Cached
  • Hypogonadism may be defined either as serum concentration of T (either total T, bioavailable T or free T) or as low T plus symptoms of hypogonadism
  • The Baltimore Longitudinal Study on Aging reported the incidence of total serum T < 325 ng/dL to be 20% for men in their 60s, 30% for men in their 70s and 50% for men over 80
  • The Massachusetts Aging Male Study reported that 12.3% of men aged 40 to 70 had a total serum T of < 200 ng/dL with 3 or more symptoms of hypogonadism
  • ...19 more annotations...
  • The Boston Area Community Health Study reported that 5.6% of men aged 30 to 70 were hypogonadal, as defined by total serum T < 300 ng/dL; or, free serum T < 5 ng/dL plus 3 or more symptoms of hypogonadism
  • In a health screening project among 819 men in Taiwan, the prevalence of hypogonadism (total serum T < 300 ng/dL) ranged from 16.5% for men in their 40s, 23.0% for men in their 50s, 28.9% for men in their 60s, and 37.2% for men older than 70 years of age
  • The prevalence of hypogonadism among men in Taiwan is higher than the prevalence reported in the Massachusetts Male Aging Study
  • CAG repeat sequence, within the androgen receptor (AR). Rajender et al[12] reviewed over 30 studies on the AR trinucleotide repeat and infertility
  • suggestion that CAG repeat length may determine androgen responsiveness, this issue is not clearly settled
  • reported prevalence of low T in older men range from 5.6% to 50%
  • Those in the hypogonadal group (n = 4269) had direct health care costs, that exceeded the eugonadal group (n = 4269) by an average of $7100 over the course of the observation window
  • higher economic burden and presence of co-morbidities for hypogonadism
  • minor to moderate improvements in lean mass and muscle strength
  • increased bone mineral density
  • modest enhancement in sexual function
  • reduced adiposity
  • lessening of depressive symptoms
  • Meta-analyses of clinical TRT trials as of 2010 have identified three major adverse events resulting from TRT: (1) polycythemia; (2) an increase in prostate-related events; and (3) and a slight reduction in serum high-density lipoprotein (HDL) cholesterol
  • polycythemia (> 3.5-fold increase in risk
  • TRT produced a 40% prostate enlargement in older hypogonadal male Veterans over 12 mo
  • no published analysis has reported measurable increases in prostate cancer risk or Gleason score in men undergoing TRT, or in hypogonadal men with a history of prostate cancer undergoing TRT
  • the prostate which highly expresses the type II 5α-reductase enzyme. Inhibition of this enzyme via finasteride (a type II 5α-reductase inhibitor) or dutasteride (a dual type I and II 5α-reductase inhibitor) reduces circulating DHT 50%-75% and > 90%, respectively[47], and reduces prostate mass[48] and prostate cancer risk
  • Normally estradiol partially regulates testosterone levels, at the hypothalamus, blunting LH and FSH release from the pituitary. As a selective estrogen receptor modulator, CC interrupts this pathway, and consequently there is a greater stimulation for the production of testosterone in Leydig cells
    • Nathan Goodyear
      Nathan Goodyear on 28 Apr 15
       
      this would only apply if E1 and/or E2 levels were elevated, which the authors make no mention of.
  • Nathan Goodyear on 28 Apr 15
     
    to be read
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Testosterone Replacement Alone for Testosterone Deficiency Syndrome Improves Moderate L... - 0 views

www.ncbi.nlm.nih.gov/...PMC3640152 low T low testosterone LUTS prostate men male hormone hormones testosterone
shared by Nathan Goodyear on 27 May 15 - No Cached
  • Nathan Goodyear on 27 May 15
     
    Study finds that Testosterone therapy reduces LUTS in men with low T.  The definition of low T is a little wide in this study.  Another study that contradicts the belief that Testosterone contributes to LUTS through the prostate.
3More

Cambridge Journals Online - Abstract - Insulin Resistance Alzheimer's Disease: Pathophy... - 0 views

journals.cambridge.org/...displayAbstract alzheimer's insulin resistance disease APOE e4 allele
shared by Nathan Goodyear on 20 Feb 11 - No Cached
  • Insulin's effects on cognition may reflect normal regulation of glucose metabolism, long-term potentiation, and neurotransmitter levels
  • future therapeutic trials should consider the moderating effects of APOE genotype.
  • Nathan Goodyear on 20 Feb 11
     
    Insulin negatively impacts memory and cognitive function
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Environmental Health | Abstract | Arsenic in drinking water and cerebrovascular disease... - 0 views

www.ehjournal.net/...abstract Arsenic drinking water environmental health
shared by Nathan Goodyear on 08 Mar 11 - No Cached
  • suggest that exposure to low-to-moderate levels of arsenic in drinking water may be associated with several of the leading causes of mortality
  • Nathan Goodyear on 08 Mar 11
     
    low levels of Arsenic in drinking water contribute to cerebrovascular disease, diabetes, and cancer
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Minimum amount of physical activity for reduced mortality and extended life expectancy:... - 0 views

www.thelancet.com/...abstract minimum exercise healthy reduced mortality
shared by Nathan Goodyear on 30 Aug 11 - No Cached
  • 15 min a day or 90 min a week of moderate-intensity exercise might be of benefit
  • Nathan Goodyear on 30 Aug 11
     
    Just 15 mins a day of exercise reduce mortatlity
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Leucine-enriched essential amino acid supplementation during moderate steady state exer... - 0 views

www.ajcn.org/...809.abstract Leucine BCAA branch chain amino acids muscle athlete athletics post exercise protein synthesis
shared by Nathan Goodyear on 10 Oct 11 - No Cached
  • Nathan Goodyear on 10 Oct 11
     
    leucine shown to increase muscle protein synthesis post exercise
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Nonalcoholic Fatty Liver Disease - 0 views

diabetes.diabetesjournals.org/...1844.short nonalcoholic fatty liver disease metabolic syndrome
shared by Nathan Goodyear on 06 Apr 11 - No Cached
  • aracterized by clinical and laboratory data similar to those found in diabetes and obesity. NAF
  • We concluded that NAFLD, in the presence of normoglycemia and normal or moderately increased body weight, is ch
  • aracterized by clinical and laboratory data similar to those found in diabetes and obesity. NAF
  • ...1 more annotation...
  • LD may be considered an additional feature of the metabolic syndrome, with specific hepatic insulin resistance
  • Nathan Goodyear on 06 Apr 11
     
    Fatty Liver is component of Metabolic Syndrome
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