Converging pathways lead to overproduction of IL-17 in the absence of vitamin D signaling - 0 views
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Nathan Goodyear on 31 Jul 13Low vitamin D levels or the receptors for vitamin D appear to result in an increase in Th17 cells. An increase in Th17 cells will lead to an imbalance with Treg cells and this imbalance is associated with Lupus and other autoimmune processes. Vitamin D inhibits Th17 cell activation.