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Nathan Goodyear

Thyroid Insufficiency. Is TSH Measurement the Only Diagnostic Tool? | DeepDyve - Resear... - 0 views

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    In study of 832 clients, TSH poorly correlated with hypothyroidism
Nathan Goodyear

Sensitivity and specificity of six tests for the diagnosis of adult... - PubMed - NCBI - 0 views

  • ARG plus GHRH test, high sensitivity (96 and 95%, respectively) and specificity (92 and 91%, respectively) for GH deficiency were achieved
  • The greatest diagnostic accuracy occurred with the ITT and the ARG plus GHRH test
  • 95% specificity could be achieved with the ARG plus L-DOPA and ARG tests only with very low peak GH cut-points (0.25 and 0.21 microg/liter, respectively) and not at all with the L-DOPA test
  • ...1 more annotation...
  • Although serum IGF-I levels provided less diagnostic discrimination than all five GH stimulation tests, a value below 77.2 microg/liter was 95% specific for GH deficiency
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    study evaluated 6 tests for HGH deficiency diagnosis.  Ninety-five percent specificity found with ARG + l-DOPA and ARG alone.  However, the authors found a 95% specificity with IGF-1 < 77.  Although, IGF-1 is false negative in up to 65% of those with HGH deficiency.
Nathan Goodyear

http://pediatrics.aappublications.org/content/pediatrics/136/6/1154.full.pdf - 0 views

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    good review of the physiology behind adolescent PCOS.  Though I hate this term because it treats PCOS as a diagnostic disease when it is simply a metabolically induced hormone balance.
cityxrayclinic

CT Angiography in Delhi - Coronary Angiography in Delhi - 0 views

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    CT Angiography or CTA stands for "Computed Tomography Angiography". It is a computed tomography technique which is mainly used to study the arteries and veins of the body. City x-ray and Scan Clinic (P) Ltd is one of the best diagnostic center in Delhi, which offers best CT Angiography facilities. You can book a test and get the reports online. Here you will have Somatom Definition AS 194 slice/sec most advanced Multi Slice Spiral CT Scanner from Siemens.
Nathan Goodyear

Thyroid Hormone Signaling Pathway - Creative Diagnostics - 0 views

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    Not a research article, but nice graphic with accompanied review.
Nathan Goodyear

Neoplastic Fever: Pathophysiology, Clinical Features, And Diagnostic Assessment - Clini... - 0 views

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    Nice article review.
mothertobehyd

Deccan Hospital - Best Hospital in Hyderabad - 0 views

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    Deccan Hospital is one of the best hospital in Hyderabad; we are providing best-in-class diagnostics and treatment services. The facility is known as one of the best tertiary care multi-super specialty hospitals in India. With world-renowned doctors and the best of medical facilities.
pharmacybiz

Avacta Halts Sale Of Covid-19 Rapid Antigen LFT - 0 views

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    Britain's biotech firm Avacta Group on Monday (January 10) announced halting sales of its Covid-19 rapid antigen lateral flow test AffiDX to replace antibodies in the device and increase its ability to diagnose the Omicron variant. The company stated that AffiDX is capable of detecting Omicron when the virus is present in high numbers in samples, but the sensitivity of the test reduces at lower viral loads. The performance of all rapid antigen tests came under scanner in wake of a large number of mutations in the Omicron variant. AffiDX contains both a proprietary Affimer reagent and a commercially available antibody. The Affimer reagent detects the Omicron variant with the same sensitivity as the Delta variant, and performance of the antibody is paired with the Affimer reagent in the test. This has been affected by the additional Omicron mutations, the firm said. Alastair Smith, chief executive of Avacta Group, said: "Our determination to only provide high quality, high performance diagnostic tests has led us to the correct decision to pause all marketing of the AffiDX® lateral flow antigen test. We have, of course, been unable to market the product in the UK since October 2021, as the product continues to await approval under the new CTDA regulatory process.
harshitatyagi

Hysteroscopy and Its Role in IVF - 0 views

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    Hysteroscopy is a less-invasive diagnostic procedure in fertility treatments like in vitro fertilization (IVF). The process involves inserting a small, lighted telescope known as a hysteroscope through the vagina and cervix and into the uterus. Lets explore the role of hysteroscopy in IVF, benefits, Risks, procedure etc.
Nathan Goodyear

Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implic... - 0 views

  • molecular chaperones
  • property of modifying the structures and interactions of other proteins
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    heat shock proteins (HSP) and cancer.  They can be useful as biomarkers for some specific cancers.  HSP are normally biologically active, but are increased in cancer.
Nathan Goodyear

Diagnostic significance of salivary testosterone measurement revisited: using liquid ch... - 0 views

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    salivary testosterone, as measured by LC-MS and ELISA, showed strong correlation with serum free "calculated" testosterone.
Nathan Goodyear

Androgen insufficiency in women: diagnostic and therapeutic implications - 0 views

  • SHBG has a differing binding affinity for sex steroids in the following order; DHT &gt; testosterone &gt; androstenedione &gt; estradiol &gt; estrone
  • SHBG also weakly binds DHEA, but not DHEAS
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    Good discuss of androgen deficiency in women.  Also, good discussion of SHBG.  
Nathan Goodyear

Diagnostic Pathology | Full text | Estrogen receptor beta expression in prostate adenoc... - 0 views

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    ER beta and prostate cancer.  More aggressive prostate cancer is found to be associated with lower ER beta expression in the prostate.  this makes sense, as other studies have shown that ER beta in the prostate can induce apoptosis (cell death), which is a powerful mechanism to regulate uncontrolled growth as found in cancer.
Nathan Goodyear

Diagnostic significance of free salivary testosterone measurement using a direct lumine... - 0 views

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    salivary testosterone found to correlate will with blood free testosterone in men.
Nathan Goodyear

Hypothyroidism and hyponatraemia: diagnostic relevance of ADH measurement - 0 views

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    hypothyroidism and hyponatraemia.  Interesting point that the patient was started on T4/T3 therapy.
Nathan Goodyear

Routine Epstein-Barr Virus Diagnostics from the Laboratory Perspective: Still Challengi... - 0 views

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    Good review of lab perspective on EBV.
Nathan Goodyear

SALIVARY CORTISOL ASSAYS FOR ASSESSING PITUITARY-ADRENAL RESERVE - PETERS - 2008 - Clin... - 0 views

  • Since salivary cortisol concentrations were shown to reflect the free, biologically active fraction in plasma, salivary assay may, in selected cases, provide results of greater diagnostic significance than plasma total concentrations.
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    salivary cortisol found to be superior to total serum cortisol levels.
Nathan Goodyear

NIH Fact Sheets - Salivary Diagnostics - 0 views

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    NIH supports saliva testing.
Nathan Goodyear

Diagnostic Potential of Saliva: Current State and Future Applications - 0 views

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    saliva testing is the new "gold standard" for hormone evaluation.  No testing method is perfect and thus there are guidelines for salivary collections.  However, saliva is equal too or superior to blood for hormone evaluation.
Nathan Goodyear

Exposure to diagnostic radiation and risk of breast cancer among carriers of BRCA1/2 mu... - 0 views

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    radiation from mammograms shown to increase cancer risk in those with BRCA mutations. IN this cohort, the risk was found in those under 30 years of age. In this study, they suggested MRI as a safer alternative. But, what about thermograms?
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