Normalization of testosterone level is associated with reduced incidence of myocardial ... - 0 views
eurheartj.oxfordjournals.org/...eurheartj.ehv346
low T low Testosterone men Testosterone mortality stroke MI CVD cardiovascular disease hormones male
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Normalized-TRT group had significantly fewer deaths than no-TRT
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Mortality was also significantly lower in the non-normalized-TRT group compared with those in no-TRT group
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the normalized-TRT group was associated with significantly increased all-cause mortality-free survival (log-rank, P < 0.05) compared with the non-normalized-TRT or no-TRT groups
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normalized-TRT group showed lower risk of MI than non-normalized-TRT (HR: 0.82, CI 0.71–0.95, P = 0.008) and no-TRT
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normalized-TRT group had significantly lower stroke events compared with non-normalized-TRT (HR: 0.70, CI 0.51–0.96, P = 0.028) and no-TRT
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study of men with low TT levels and without prior MI or stroke, normalization of TT levels using TRT is associated with lower all-cause mortality, fewer MIs, and ischaemic strokes
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the first study to demonstrate that significant benefit is observed only if the dose is adequate to normalize the TT levels
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Patients who failed to achieve the therapeutic range after TRT did not see a reduction in MI or stroke and had significantly less benefit on mortality
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selected patients without any previous history of MI or stroke prior to initiation of TRT to reduce bias related to CV outcomes
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25% of users did not have their T concentrations tested prior to initiating therapy, and 21% of those prescribed TRT did not have their levels tested at any time during treatment.
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men without a history of previous MI or stroke who have low TT levels, TRT might be associated with decreased risks of MI, ischaemic stroke, and all-cause mortality in long-term follow-up