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Nathan Goodyear

Vitamin D Deficiency and Its Association with Thyroid Disease - 0 views

www.ncbi.nlm.nih.gov/...PMC3921055

vitamin d hypothyroidism hypothyroid thyroid calcium hormones

shared by Nathan Goodyear on 07 Feb 16 - No Cached
  • Nathan Goodyear on 07 Feb 16
     
    low vitamin D is not only associated with hypothyroidism; but also the severity of hypothyroidism.  Low calcium is also associated with hypothyroidism.
Nathan Goodyear

Effect of Levothyroxine Replacement on Lipid Profile and Intima-Media Thickness in Subc... - 0 views

jcem.endojournals.org/...2099.long

levothyroxin subclinical hypothyroidism functional hypothyroidism hypothyroid lipids hypothyroidism cholesterol metabolism thyroid IMT

shared by Nathan Goodyear on 27 Jul 13 - No Cached
  • Nathan Goodyear on 27 Jul 13
     
    synthetic T4, as levothyroxine, in subclinical hypothyroidism is shown to improve cholesterol levels and intima-media thickness.
Nathan Goodyear

Subclinical hypothyroidism in young women with... [Fertil Steril. 2013] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...23103018

PCOS polycystic ovarian syndrome hypothyroid hypothroidism functional hypothyroidism women female hormone hormones

shared by Nathan Goodyear on 14 May 14 - No Cached
  • Nathan Goodyear on 14 May 14
     
    Link exists between PCOS and subclinical hypothyroidism.  Another term is functional hypothyroidism.
Nathan Goodyear

Hyponatremia and the Thyroid: Causality or Association? - 0 views

www.ncbi.nlm.nih.gov/...PMC4470237

hypothyroid hypothyroidism hyponatremia sodium thyroid

shared by Nathan Goodyear on 23 May 16 - No Cached
  • Nathan Goodyear on 23 May 16
     
    hypothyroidism and hyponatremia is a rare finding; more commonly associated with severe hypothyroidism.  Co-exisitng medical complications need to be considered.
Nathan Goodyear

elements of oxidation/reduction balance in experimental hypothyroidism - 0 views

www.spectracell.com/...-balance-in-hypothyroidism.pdf

hypothyroid hypothyroidism glutathione perioxidase SOD super oxide dismutase antioxidant

shared by Nathan Goodyear on 01 Feb 12 - No Cached
  • Nathan Goodyear on 01 Feb 12
     
    hypothyroidism decreases antioxidant enzyme activity of SOD and glutathione perioxidase.
Nathan Goodyear

Acute severe hypothyroidism is not associated with hyponatremia even with increased wat... - 0 views

bmcendocrdisord.biomedcentral.com/...1472-6823-13-27

hypothyroid hypothyroidism hyponatremia sodium cancer

shared by Nathan Goodyear on 23 May 16 - No Cached
  • Nathan Goodyear on 23 May 16
     
    study finds severe hypothyroidism that is abrupt is not associated with low sodium.
Nathan Goodyear

Hypothyroidism associated with anti-huma... [J Endocrinol Invest. 2003] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...15008254

autoimmune disease HCG anti-HCG hypothyroid hypothyroidism

shared by Nathan Goodyear on 15 May 12 - No Cached
  • Nathan Goodyear on 15 May 12
     
    a case report of anti-HCG antibodies in a 22 year old male on HCG therapy for idiopathic hypothalamic hypogonadism.  the Result was an autoimmune hypothyroidism as a result of the anti-HCG.
Nathan Goodyear

The Natural History of Subclinical Hypothyroidism in the Elderly: The Cardiovascular He... - 0 views

jcem.endojournals.org/...1962.abstract

subclinical hypothyroidism hypothyroidism elderly health

shared by Nathan Goodyear on 27 Jun 12 - No Cached
  • Nathan Goodyear on 27 Jun 12
     
    subclinical hypothyroidism is alarmingly high in elderly population--56%.
Nathan Goodyear

Combination Treatment with T4 and T3: Toward Personalized Replacement Therapy in Hypoth... - 0 views

jcem.endojournals.org/...2256.abstract

armour thyroid hypothyroid hypothyroidism T4 T3

shared by Nathan Goodyear on 27 Jul 12 - No Cached
  • Nathan Goodyear on 27 Jul 12
     
    Wow!  JCEM states, "...it may be time to consider a personalized regime of thyroid hormone replacement therapy in hypothyroid patents."  Otherwise stated, combination T4, T3 provides a more customized thyroid replacement therapy than synthroid alone.
Nathan Goodyear

Effect of treatment of overt hypothyroidism on insulin resistance - 0 views

www.ncbi.nlm.nih.gov/...PMC3746089

hypothyroid hypothyroidism insulin resistance thyroid hormone hormones

shared by Nathan Goodyear on 09 Sep 13 - No Cached
  • Nathan Goodyear on 09 Sep 13
     
    Thyroid treatment in those with hypothyroidism and insulin resistance provided no benefit to the insulin resistance.  But, Total cholesterol did improve. 
Nathan Goodyear

Combination Treatment with T4 and T3: Toward Personalized Replacement Therapy in Hypoth... - 0 views

press.endocrine.org/...jc.2011-3399

hypothyroid hypothyroidism T4 T3 thyroid metabolism hormones

shared by Nathan Goodyear on 24 Sep 14 - No Cached
  • Nathan Goodyear on 24 Sep 14
     
    reference review suggests improved results with combined T4/T3 treatment for hypothyroid patients.  Also, a good review of thyroid metabolism.  Patients prefer the combination therapy versus T4 alone indicating improved symptoms with combined therapy.
Nathan Goodyear

Metabolic Effects of Liothyronine Therapy in Hypothyroidism: A Randomized, Double-Blind... - 0 views

press.endocrine.org/...jc.2011-1329

T4 T3 hypothyroid hypothyroidism thyroid lipids weight loss metabolism cholesterol hormones

shared by Nathan Goodyear on 24 Sep 14 - No Cached
  • tissue euthyroidism is the net result of multiple steps including conversion of the prohormone T4 into its active metabolite T3, which is ultimately responsible for signaling at the end-organ target level
  • The circulating and intracellular pools of T3 of treated hypothyroid patients (i.e. devoid of endogenous TH production) depend entirely on the conversion of exogenous l-T4 into T3
  • TH is the major regulator of basal metabolic rate
  • ...8 more annotations...
  • The substitution of l-T3 for l-T4 caused a significant weight loss
  • The substitution of l-T3 for l-T4 caused a significant reduction in lipid parameters
  • TH action is increased in the liver, and the SHBG increase supports this hypothesis
  • The changes in serum lipid metabolism parameters are similar to the effects observed with drugs approved for the treatment of dyslipidemia
  • This differential response appears to be limited to the lipid metabolism and SHBG, whereas no differences in indices of insulin resistance were detected. This is remarkable because hyperthyroid states are associated with an increase in hepatic gluconeogenesis (37), and overt thyrotoxicosis is a known cause of secondary diabetes.
  • Despite the increase in serum T3, the l-T3 treatment did not cause major changes in cardiovascular or musculoskeletal function, as indicated by the echocardiographic and maximal exercise tolerance tests and DXA studies.
  • Similarly, no significant differences were observed in blood pressure, heart rate, or endothelial vascular function
  • In conclusion, the results of this pharmacology, proof-of-concept study indicate that replacement therapy of hypothyroidism with l-T3, compared with l-T4 causes weight loss and favorable changes in the lipid profile without appreciable side effects
  • Nathan Goodyear on 24 Sep 14
     
    Crossover study finds T3 versus T4 results in more weight loss, improved lipid management and increased SHBG without any adverse cardiovascular effects.   The T3 was dosed 3 x daily due to its short half life compared to T4.
Nathan Goodyear

The effects of treatment of subclinical hypothyroi... [Med Arh. 2007] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...17582969

subclinical hypothyroidism insulin resistance treatment hypothyroid thyroid metabolic syndrome hormone hormones

shared by Nathan Goodyear on 02 Feb 11 - No Cached
  • These data support an important role of treatment of SH in support metabolic control and insulin sensitivity.
  • Nathan Goodyear on 02 Feb 11
     
    Treatment of sub-clinical hypothyroidism required to improve insulin resistance
Nathan Goodyear

Subclinical hypothyroidism: deciding when to treat. [Am Fam Physician. 1998] - PubMed r... - 0 views

www.ncbi.nlm.nih.gov/...9491000

hypothyroid hypothyroidism treatment

shared by Nathan Goodyear on 19 Nov 10 - No Cached
  • Nathan Goodyear on 19 Nov 10
     
    Subclinical hypothyroidism: deciding when to treat.
Nathan Goodyear

L-Thyroxine therapy in subclinical hypothyroidism.... [Ann Intern Med. 1984] - PubMed r... - 0 views

www.ncbi.nlm.nih.gov/...6428290

Hypothyroid hypothyroidism therapy

shared by Nathan Goodyear on 19 Nov 10 - No Cached
  • Nathan Goodyear on 19 Nov 10
     
    Treatment in subclinical hypothyroidism provides statistical benefits to patient symptoms
Nathan Goodyear

Elevated C-reactive protein and homocysteine value... [Atherosclerosis. 2003] - PubMed ... - 0 views

www.ncbi.nlm.nih.gov/...12535752

hypothyroidism hypothyroid CRP

shared by Nathan Goodyear on 01 Feb 11 - No Cached
  • This is the first paper to show that CRP values increase with progressive thyroid failure and may count as an additional risk factor for the development of coronary heart disease in hypothyroid patient
  • Nathan Goodyear on 01 Feb 11
     
    inflammation, CRP, associated with hypothyroidism
Nathan Goodyear

TSH is a poor measure of severity of tissue hypothyroidism - 0 views

www.ncbi.nlm.nih.gov/...PMC1125164

hypothyroid hypothyroidism TSH

shared by Nathan Goodyear on 08 Mar 11 - No Cached
  • Thyroid stimulating hormone (TSH) tests are not useful for estimating the clinical and metabolic severity of primary overt thyroid failure. Meier and colleagues (p311) found that, in contrast with the accuracy of serum TSH measurement in the early diagnosis of hypothyroidism, clinical markers and circulating thyroid hormones much more accurately reflect the degree of tissue hypothyroidism. Initiation of replacement therapy should be guided by clinical presentation and circulating thyroid hormones and not by TSH concentrations
  • Nathan Goodyear on 08 Mar 11
     
    TSH is not a useful test
Nathan Goodyear

Diagnosis and Treatment of Hypothyroidism - 0 views

www.mercola.com/...diagnosis_comp.aspx

hypothyroidism treatment diagnosis

shared by Nathan Goodyear on 08 Mar 11 - No Cached
  • Nathan Goodyear on 08 Mar 11
     
    good overall read on hypothyroidism from Dr. Mercola
Nathan Goodyear

Plasma concentration of gonadotrophins,... [Br J Obstet Gynaecol. 1975] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...1148139

hormone hormones estrogen progesterone hypothyroid hypothyroidism

shared by Nathan Goodyear on 03 Jun 13 - No Cached
  • Nathan Goodyear on 03 Jun 13
     
    Sex hormone imbalance plays a role in hypothyroidism.
Nathan Goodyear

Persistent Subclinical Hypothyroidism and Cardiovascular Risk in the Elderly: The Cardi... - 0 views

jcem.endojournals.org/...533.abstract

subclinical hypothyroidism TSH cardiovascular elderly health

shared by Nathan Goodyear on 08 Feb 13 - No Cached
  • Nathan Goodyear on 08 Feb 13
     
    study finds no increased risk of CHD, HF, or CV death in subclinical hypothyroidism in older adults.  No insight is gained from this article, due to the use of TSH as the only tool for thyroid assessment.  TSH has been shown to become unreliable as a sole thyroid assessment tool an aging population.
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