Mitochondrial electron-transport chain and other oxidizing agents are the prime pathways that generate excess ROS in vivo
Permanent modification of genetic material resulting from the oxidative damage is one of the vital steps involved in mutagenesis that leads to carcinogenesi
The most frequent DNA mutations caused during oxidative stress, initiated by ionizing radiation and other environmental carcinogens are 7,8-dihydro-8-oxoguanine (8-Oxo-G) and Thymine Glycol (TG)
Chronic pain treatments are as varied as its causes. There are numerous approaches available, ranging from over-the-counter and prescription drugs to mind/body techniques and acupuncture. However, when it comes to treating chronic pain, no single technique can guarantee complete pain relief. A combination of treatment options may provide relief.