The Potential Role of Systemic Buffers in Reducing Intratumoral Extracellular pH and Ac... - 0 views
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Nathan Goodyear on 19 Nov 18Great diagram of the pH in/around solid tumors. Cancer exists in an obvious hypoxic environment which favors the HIF-1alpha which favors lactate production which drops the pH in the tumor extracellular environment effecting chemoresistance, radioresistance, angiogenesis, invasion, aggressiveness, metastasis, immune evasion...