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spineneuro

https://www.101pressrelease.com/financial-freedom-through-vbt-planning-for-surgery-expe... - 0 views

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    The prominence of the cost of VBT surgery is a significant consideration for international patients opting for this procedure in the country. Simultaneously, the cost of VBT surgery is comparatively lower, making it a prudent choice for patients seeking surgical treatment.
spineneuro

Expert ENT Care in India: Top Specialists You Can Trust - 0 views

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    The 12 best ENT specialists in India are often associated with top-tier hospitals that cater to international patients. They offer streamlined services, including assistance with travel, accommodation, and language translation, ensuring a hassle-free experience. Despite offering world-class services, the 12 best ENT specialists in India provide treatments at a fraction of the cost compared to many Western countries.
Nathan Goodyear

L-Thyroxine therapy in subclinical hypothyroidism.... [Ann Intern Med. 1984] - PubMed r... - 0 views

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    Treatment in subclinical hypothyroidism provides statistical benefits to patient symptoms
Nathan Goodyear

Arch Intern Med -- Vitamin D2 Treatment for Vitamin D Deficiency and Insufficiency for ... - 0 views

  • may be less effective than cholecalciferol (vitamin D3)
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    Long term high dose Vitamin D proven to be effective.  No toxicity.
Nathan Goodyear

Effect of dietary GLA+/−tamoxifen on the growth, ER expression and fatty acid... - 0 views

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    GLA enhances the effectiveness of tamoxifen in the treatment of ER + breast cancer
Nathan Goodyear

International Journal of Obesity - Antiobesity action of peripheral exenatide (exendin-... - 0 views

  • Systemic exenatide reduces body weight gain in normal, high-fat-fed rodents
  • role in metabolic pathways mediating food intake.
  • the first of which to be identified was an enhancement of glucose-dependent insulin secretion
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  • limits glucose appearance via glucose-dependent slowing of gastric emptying
  • suppression of inappropriately elevated postprandial glucagon secretion
  • promote pancreatic -cell proliferation and islet cell neogenesis in both animal and in vitro studies
  • short-term regulator of food intake
  • eceptor agonism in satiety
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    exanatide helps in obesity and fatty liver treatment
Nathan Goodyear

National Institutes of Health Pathways to Prevention Workshop: The Role of Opioids in t... - 0 views

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    NIH panel review finds little empirical evidence to support the use of opioids in chronic pain.
Nathan Goodyear

Testosterone and benign prostatic hyperplasia Jarvis TR, Chughtai B, Kaplan SA, - Asian... - 0 views

  • The prevalence of hypogonadism (often defined as serum testosterone < 300 ng dl−1 ) ranges from 6% [10] to as high as 38%
  • The process of BPH, however, continues as men age and despite the fact their serum testosterone decreases
  • Liu et al. [12] demonstrated that in a group of older males (mean age 59.8 years) that there was not a significant correlation of serum testosterone levels (total, free or bioavailable) with either prostate volume or International Prostate Symptom Score (IPSS)
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  • in eugonadal men, studies have demonstrated that the prostate can increase in volume by approximately 12%
  • There seems to be little doubt that the treatment with testosterone of a young hypogonadal male leads to significant growth of the prostate
  • Behre et al. [22] demonstrated increased prostate volume and prostate-specific antigen (PSA) levels in hypogonadal men
  • Most studies, however, have shown no effect of exogenous androgens on PSA or prostate volume for older hypogonadal males
  • They argue that the prostate is relatively insensitive to changes in androgen concentration at normal levels or in mild hypogonadism because the AR is saturated by androgens and therefore maximal androgen-AR binding is achieved. Conversely, the prostate is very sensitive to changes in androgen levels when testosterone is low
  • saturation model
  • visceral obesity (one of the most significant components of metabolic syndrome) is associated with prostate volume and influences prostate growth during TRT.
  • This hypothesis of inflammation induced LUTS is also argued to be a mechanism for improvement of LUTS with PDE5I
  • The concept, therefore, that treatment with TRT of hypogonadal males with metabolic syndrome might lead to improvement/stabilization of their LUTS, appears to be confirmed in recent work by Francomano et al.
  • There was also an improvement in components of the patient's metabolic syndrome (such as BMI, waist circumference, hemoglobin A1c [HbA1c], insulin sensitivity, and lipid profile) as well as inflammatory markers and C-reactive protein.
  • They concluded that TRT was safe in this group of men, and hypothesize that TRT mitigates the pro-inflammatory factors associated with metabolic syndrome.
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    Authors review the literature behind Testosterone and BPH.  The authors highlight the 4 proposed theories behind BPH: Testosterone, Estrogen, inflammation, and metabolic.   The conclusion is mixed: pointing out that no high level of evidence exists on either side of the debate of Testosterone and BPH.
spineneuro

untitled - 0 views

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    Selecting the best hospital brain cancer surgery is essential to ensure access to specialized expertise, comprehensive care, advanced technology, innovative treatments, quality assurance, and personalized support that can optimize outcomes and improve the overall experience for patients and their families.
Nathan Goodyear

Fourth International Consultation on Incontinence Recommendations of the International ... - 0 views

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    exposure rates up to 19% in level 1 studies.
Nathan Goodyear

Annals of Internal Medicine | Long-Term Effects of Dihydrotestosterone Treatment on Pro... - 0 views

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    DHT at 70 mg daily shown to have no adverse effects in the prostate of "healthy" men older than 50.  However, it did increase DHT metabolites (3 alpha androstane-diol and 3 beta androstane-diol), decreased LH, Testosterone, Estradiol, FSH, increased hemoglobin, creatinine, lean mass and decreased fat.
Nathan Goodyear

Postmenopausal hormone use and risk for color... [Ann Intern Med. 1998] - PubMed - NCBI - 0 views

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    Study finds that HRT is associated with a 35% reduction in relative risk of colorectal cancer in postmenopausal women.  Even use within the previous 5 years was associated with reduced risk.  This benefit is lost at 5 years..
Nathan Goodyear

Arch Intern Med -- Abstract: The Progressive Cost of Complications in Type 2 Diabetes M... - 0 views

  • Per-person costs increased over baseline ($2033) by more than 50% ($1087) after initiation of cardiovascular drug therapy and/or use of a cardiologist, and by 360% ($7352) after a major cardiovascular event. Abnormal renal function increased diabetes treatment costs by 65% ($1337); advanced renal disease, by 195% ($3979); and end-stage renal disease, by 771% ($15,675)
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    Costs of "poor health"
Nathan Goodyear

Arch Intern Med -- Abstract: Human Chorionic Gonadotropin (HCG) Treatment of Obesity, F... - 0 views

  • hese results indicate that HCG has no effects on chemical and hormonal parameters measured and offers no advantage over calorie restriction in promoting weight loss.
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    HCG injections appear to have no effect on weight loss over those following 500 cal diets
Nathan Goodyear

A conceptually new treatment approach for relapsed glioblastoma: Coordinated underminin... - 0 views

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    first publication that I can find.
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