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Nathan Goodyear

Vitamin C Function in the Brain: Vital Role of the Ascorbate Transporter (SVCT2) - 0 views

www.ncbi.nlm.nih.gov/...PMC2649700

vitamin C antioxidant antioxidants excitotoxicity Alzheimer's disease Parkinson's Huntingdon's brain

shared by Nathan Goodyear on 08 Mar 12 - No Cached
  • Nathan Goodyear on 08 Mar 12
     
    vitamin C proposed to have therapeutic effect in those with stroke, Alzheimer's disease, Parkinson's disease, and Huntingdon's disease.
Nathan Goodyear

PLOS ONE: N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson's Disease: Prelim... - 0 views

journals.plos.org/...article

Parkinsons Parkinson's disease NAC N-acetylcysteine brain

shared by Nathan Goodyear on 17 Jun 16 - No Cached
  • Nathan Goodyear on 17 Jun 16
     
    pilot study finds that NAC protects the dopaminergic neurons in the brains in cell line stud.  Clinical found increased dopamine binding in the brain compared to placebo in individuals with Parkinson's disease.
Nathan Goodyear

Redox imbalance in Parkinson's disease. [Biochim Biophys Acta. 2008] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...18358848

Parkinson's disease ROS oxidative stress dopamine

shared by Nathan Goodyear on 14 Dec 11 - No Cached
  • Nathan Goodyear on 14 Dec 11
     
    oxidative stress and Parkinson's disease
Nathan Goodyear

Glutathione, iron and Parkinson's disease. [Biochem Pharmacol. 2002] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...12213603

Glutathione Parkinson's neurodegenerative disease Iron Fe

shared by Nathan Goodyear on 14 Dec 11 - No Cached
  • Nathan Goodyear on 14 Dec 11
     
    Glutathione restoration should be an important role in people with Parkinson's Disease
Nathan Goodyear

Reduced intravenous glutathione in the treatment of early parkinson's disease 10.1016/S... - 0 views

www.sciencedirect.com/...S0278584696001030

IV intravenous glutathione Parkinson's disease PD

shared by Nathan Goodyear on 09 Mar 12 - No Cached
  • Nathan Goodyear on 09 Mar 12
     
    IV glutathione shown to slow profession of Parkinson's Disease.  IV was given at doses of 600 mg IV twice daily for 30 days.
Nathan Goodyear

Low LDL cholesterol and increased risk of Parkins... [Mov Disord. 2008] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...18381649

LDL cholesterol Parkinson's parkinson's disease neurodegenerative disease

shared by Nathan Goodyear on 14 Jun 12 - No Cached
  • Nathan Goodyear on 14 Jun 12
     
    individuals with the lowest LDL associated with a 350% increase rate of Parkinson's disease.
Nathan Goodyear

Oxidative stress and mitochondrial dysfunction in ... [Biochem Mol Biol Int. 1994] - Pu... - 0 views

www.ncbi.nlm.nih.gov/...7849618

stress oxidative mitochondrial Parkinson's neurodegenerative disease

shared by Nathan Goodyear on 08 Feb 11 - No Cached
  • neurodegenerative disorders such as Parkinson's disease mitochondrial dysfunction and oxidative stress may cause or worsen the clinical features.
  • Nathan Goodyear on 08 Feb 11
     
    mitochondrial dysfunction contributes, even cause many neurodegenerative disease, such as Parkinson's
Nathan Goodyear

Mitochondria: a therapeutic target in neurodegener... [Biochim Biophys Acta. 2010] - Pu... - 0 views

www.ncbi.nlm.nih.gov/...19853657

mitochondria Alzheimer's Parkinson's Huntington's ALS neurodegenerative disease

shared by Nathan Goodyear on 07 Feb 11 - No Cached
  • mitochondrial dysfunction has a central role in the pathogenesis of Alzheimer's, Parkinson's and Huntington's diseases and amyotrophic lateral sclerosis
  • Nathan Goodyear on 07 Feb 11
     
    mitochondrial dysfunction has a central role in the pathogenesis of Alzheimer's, Parkinson's and Huntington's diseases and amyotrophic lateral sclerosis
Nathan Goodyear

Iron and aluminum increase in the substantia nigra... [J Neurochem. 1991] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...1988548

aluminum iron Parkinson's Disease

shared by Nathan Goodyear on 12 May 11 - No Cached
  • ncreased iron levels and the detection of aluminum observed in Parkinson's disease
  • Nathan Goodyear on 12 May 11
     
    increased Iron and Aluminum levels found in Parkinson's Disease
Nathan Goodyear

Mitochondrial dysfunction in Parkinson's disease: ... [Parkinsons Dis. 2010] - PubMed r... - 0 views

www.ncbi.nlm.nih.gov/...21234411

mitochondrial dysfunction Parkinson's disease neurodegenerative

shared by Nathan Goodyear on 16 May 11 - No Cached
  • Nathan Goodyear on 16 May 11
     
    fantastic read on mitochondrial dysfunction and parkinson's disease
Nathan Goodyear

Low LDL cholesterol and increased risk of Parkinson's disease: Prospective results from... - 0 views

onlinelibrary.wiley.com/...full

LDL Parkinson's disease

shared by Nathan Goodyear on 07 Oct 11 - No Cached
  • Nathan Goodyear on 07 Oct 11
     
    study shows that low LDL increased the risk of Parkinson's disease.  Be careful to not lower your LDL too much.  LDL is not "BAD" cholesterol.
Nathan Goodyear

BioMed Central | Full text | Pesticide exposure and risk of Parkinson's disease: a fami... - 0 views

www.biomedcentral.com/...abstractResearch

pesticide exposure Parkinson's disease

shared by Nathan Goodyear on 01 Jul 11 - No Cached
  • hese data corroborate positive associations of broadly defined pesticide exposure with PD in families, particularly for sporadic PD
  • Nathan Goodyear on 01 Jul 11
     
    pesticide and Parkinson's disease
Nathan Goodyear

Mulberry fruit ameliorates Parkinson's-disease-related pathology by reducing ... - 0 views

www.jnutbio.com/...fulltext

mulberry mulberry fruit extract Parkinson's disease

shared by Nathan Goodyear on 23 May 17 - No Cached
  • Nathan Goodyear on 23 May 17
     
    full study of animal model that found neuroprotective effects of mulberry fruit extract in Parkinson's disease.
Nathan Goodyear

Mulberry fruit ameliorates Parkinson's-disease-related pathology by reducing ... - 0 views

www.ncbi.nlm.nih.gov/...27741433

mulberry mulberry fruit extract Parkinson's disease

shared by Nathan Goodyear on 23 May 17 - No Cached
  • Nathan Goodyear on 23 May 17
     
    mulberry fruit extract found to treatment option to prevent dopaminergic damage and prevention of Parkinson's disease in animal model.
Nathan Goodyear

Mulberry fruit protects dopaminergic neurons in toxin-induced Parkinson's disease model... - 0 views

www.ncbi.nlm.nih.gov/...20187987

Parkinson's disease mulberry mulberry fruit extract

shared by Nathan Goodyear on 23 May 17 - No Cached
  • Nathan Goodyear on 23 May 17
     
    Animal model finds mulberry fruit extract is neuroprotective against MPTP in Parkinson's disease in vitro and in vivo model.
Nathan Goodyear

[Hyperbaric oxygenation in the complex treatment of Parkinson disease]. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...2618228

Parkinson's disease Parkinson's hbot hyperbaric oxygen hyperbaric therapy

shared by Nathan Goodyear on 16 Jun 17 - No Cached
  • Nathan Goodyear on 16 Jun 17
     
    Hyperbaric therapy beneficial in 55 out of 64 patients with Parkinson's disease
Nathan Goodyear

Oxidative stress, mitochondrial dysfunction and ce... [J Neurol Sci. 2005] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...15896810

CoQ10 mitochondria neurodegenerative disease Alzheimer's Parkinsons MS ALS oxidative stress

shared by Nathan Goodyear on 07 Feb 11 - No Cached
  • There is significant evidence that the pathogenesis of several neurodegenerative diseases, including Parkinson's disease, Alzheimer's disease, Friedreich's ataxia (FRDA), multiple sclerosis and amyotrophic lateral sclerosis, may involve the generation of reactive oxygen species (ROS) and/or reactive nitrogen species (RNS) associated with mitochondrial dysfunction
  • Nathan Goodyear on 07 Feb 11
     
    Mitochondrial dysfunction at heart of diseases such as Parkinson's, Alzheimers, MS, ALS..
Nathan Goodyear

Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Agg... - 0 views

www.nature.com/srep34477

neurodegenerative disease amyloid alzheimer's disease Parkinson's disease gut gut flora gut microbiome gut microbiota gut-brain

shared by Nathan Goodyear on 06 Oct 16 - No Cached
  • Our work suggests that protein misfolding and immune activation in neurodegenerative disorders are triggered through cross-seeding by exposure to exogenous microbial amyloids in the nose, mouth and gut.
  • Streptococcus mutans, Staphlococcus aureus, Salmonella enterica, Mycobacterium tuberculosis and others
  • Gene homologs encoding curli were recently determined also in four phyla: Bacteroidetes, Proteobacteria, Firmicutes, and Thermodesulfobacteria
  • ...8 more annotations...
  • changes in the gut microbiota induced by antibiotics alter neuroinflammation and amyloid deposition in a mouse model of AD
  • Our data suggest that amyloid proteins in the microbiota are involved in the origination and maintenance of neurodegenerative disease.
  • exposure to bacteria producing a functional extracellular amyloid protein enhances aggregation of AS in brain neurons in aged rats and in muscle cells in nematodes
  • AS aggregates seed aggregation of tau
  • involvement of the vagus nerve in PD
  • microgliosis, astrogliosis and enhanced expression of IL-6, TLR2 and TNF in the brain following curli exposure suggest the occurrence of an enhanced local sterile inflammatory response to AS in the brain.
  • the immune system in both AD and PD have now been extensively established
  • TLR2 activation through exposure to bacterial amyloid is pathogenic
  • Nathan Goodyear on 06 Oct 16
     
    Gut bacteria may play crucial role in systemic inflammation that leads to Alzheimer's and Parkinson's disease.  These amyloid production bacteria trigger systemic inflammation that leads to microglia activation and amyloid in the brain.   More establishment of the gut-brain connection.  
Nathan Goodyear

Effect of DHEA on recovery of muscle atro... [J Korean Acad Nurs. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22310868

DHEA Parkinson's disease Parkinson's

shared by Nathan Goodyear on 02 Jun 13 - No Cached
  • Nathan Goodyear on 02 Jun 13
     
    DHEA improves muscle atrophy in Parkinson's disease.
Nathan Goodyear

Risk of Parkinson Disease Onset in Patients With Diabetes - 0 views

care.diabetesjournals.org/...1047.abstract

diabetes parkinson's disease neurodegenerative disease

shared by Nathan Goodyear on 11 Jun 12 - No Cached
  • Nathan Goodyear on 11 Jun 12
     
    Diabetes associated with an increased risk of Parkinson's disease in young men, middle aged women, and the elderly.
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