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"Berberine is a bitter-tasting, yellow, plant alkaloid with a long history of medicinal use in Chinese and Ayurvedic medicine. Berberine is present in the roots, rhizomes and stem bark of various plants including Hydrastis canadensis (goldenseal), Coptis chinensis (coptis or goldenthread), Berberis aquifolium (Oregon grape), Berberis vulgaris (barberry), and Berberis aristata (tree turmeric). Berberine has also been used historically as a dye, due to its yellow color. Clinical trials have been conducted using berberine. There is some evidence to support its use in the treatment of trachomas (eye infections), bacterial diarrhea, and leishmaniasis (parasitic disease). Berberine has also shown antimicrobial activity against bacteria, viruses, fungi, protozoans, helminths (worms), and chlamydia (STD). Future clinical research is warranted in these areas, as well as cardiovascular disease, skin disorders, and liver disorders. Berberine has been shown to be safe in the majority of clinical trials. However, there is a potential for interaction between berberine and many prescription medications, and berberine should not be used by pregnant or breastfeeding women, due to potential for adverse effects in the newborn."

"Berberine is a bitter-tasting, yellow, plant alkaloid with a long history of medicinal use in Chinese and Ayurvedic medicine. Berberine is present in the roots, rhizomes and stem bark of various plants including Hydrastis canadensis (goldenseal), Coptis chinensis (coptis or goldenthread), Berberis aquifolium (Oregon grape), Berberis vulgaris (barberry), and Berberis aristata (tree turmeric). Berberine has also been used historically as a dye, due to its yellow color. Clinical trials have been conducted using berberine. There is some evidence to support its use in the treatment of trachomas (eye infections), bacterial diarrhea, and leishmaniasis (parasitic disease). Berberine has also shown antimicrobial activity against bacteria, viruses, fungi, protozoans, helminths (worms), and chlamydia (STD). Future clinical research is warranted in these areas, as well as cardiovascular disease, skin disorders, and liver disorders.

Mango Juice are involved in the distribution, import and export of high-quality Mango Juice to our clients. Made using the best quality Mangoes, this juice is rich in nutritional content and contains no preservatives or added flavors. It is completely natural. Product specification With the help of our professionals, we have been engaged in manufacturing, exporting and supplying Mango Juice Pet Bottle. The offered juice is processed using fresh mangoes extracts to give a natural flavor. This juice is processed under the supervision of our experts under the utmost hygiene environment as per the food processing industry norms. We offer this healthy Mango Juice Pet Bottle in different capacity bottles as per the requirements of clients. Features: Rich taste Natural flavor Long shelf life Purity Mango Juice in Pet Bottles is a complete rejuvenator and helps in maintaining overall health by balancing digestive functions and cleansing the stomach. Our products are highly appreciated from various clients for accurate composition, purity and delightfully tasty. These fruits juice is very effective in case of heat strokes, which is extracted from fresh fruits, which is extremely durable. Clients can avail from us at affordable price. We supply Mango Juice in Pet Bottles which is very much nutritious, and rich in vitamins and other minerals. We manufacture these mango juices using quality mangoes nutritious as well extracted from latest technology. These mango juices offered by us natural Mango Drinks and do not contain any artificial ingredients. Our mango juice drink is refreshing, nutritious and is an abundant source of minerals and energy. Packaging Materials Packaging materials are considered to be an essential material for proper and safe delivery of goods. These are widely demanded for protecting perishable as well as non perishable goods. With the hep of these materials, different kind of commodities are packed like plastic containers,elec

Fruit Juice Leading Exporter and Distributor from Indore and Bhopal, Our products are available in a wide range of flavours and pack sizes, such as Mango Juice, Litchi Juice, Nimbu Juice, Sqeeze Mango Juice, PET Bottle Mango Juice, PET Bottle Nimbu Juice (Lemon Drink), PET Bottles Litchi Juice and many more items. All our products are made with real fruit juice or pulp. Mango Pulp used for making the drinks is made from choicest mangoes brought from South India which is the World's largest producer of Mangoes. Our assortment of juicy mango and other drinks offer essential minerals, antioxidants, fiber and vitamin A and C, and is an excellent way of repletion of lost potassium. With the help of professionals, we are capable in offering a wide range of Fruit Juice. Our offered product is processed under hygienic and pure conditions. Regular consumption of our product helps to improve energy level. Apart from this, our product is processed under the guidance of our skilled professionals keeping in mind set industry norms. We have several flavors of juice, which includes mango, litchi, Nimbu etc. Apart from this, clients can avail this product from us at a reasonable price. Features: Freshness Mouth watering taste Rich in minerals Mango Juice We are involved in the distribution, import and export of high-quality Mango Juice and Mango Drinks to our clients. Made using the best quality Mangoes, this juice is rich in nutritional content and contains no preservatives or added flavors. It is completely natural. This product is in compliance with the latest food hygiene and safety norms and is tested for its quality by certified professionals. The juice is packaged efficiently by us to retain the nutritional contents and is delivered in a timely manner through various shipment and transport modes. Features: Timely delivery and export Made from best quality Mangoes Rich nutrient content 100% natural Preservative-free Litchi Juice We distri

Multani Mitti or Fuller's earth has been used by Indian women for centuries to take care of their skincare problems like acne, blackheads, etc. Though most modern women now prefer to use branded products, they could still try using the humble F ...

Multani Mitti or Fuller's earth has been used by Indian women for centuries to take care of their skincare problems like acne, blackheads, etc. Though most modern women now prefer to use branded products, they could still try using the humble F ...

The lemon is a small evergreen tree native to Asia. The tree's ellipsoidal yellow fruit is used for culinary and non-culinary purposes throughout the world, primarily for its juice, though the pulp and rind (zest) are also used in cooking and baking. http://mangodash.blogspot.in/2014/10/evergreen-lemon-juice-uses.html http://www.mangodashindia.com/

Simultaneously Blocking Glycolysis and Fat Metabolism Can the use of DCA and a fatty acid metabolism blocker together force more cancer cells into using aerobic metabolism? Tim McGough used green tea extract, which contains EGCG, in his fantastic response. DCA works by reactivating mitochondria and shifts metabolism from glycolysis to glucose oxidation. Hopefully the cancer cell will then undergo apoptosis. However, cancer cells have an alternate energy source: fat metabolism. This page explores to possibility of blocking fat metabolism to help force the cell into apoptosis. Oral squamous cell carcinoma is a cancer that does not respond well to DCA. This study, Head and Neck Cancer Cell Lines Are Resistant to Mitochondrial-Depolarization-Induced Apoptosis states: "Results: ΔΨm in head and neck cell lines started to show slight loss of ΔΨm, while HL-60 showed significant loss of ΔΨm after 30 min of treatment. All cell lines demonstrated complete mitochondrial depolarization within 24 h, however, only the control cell line HL-60 underwent apoptosis. In addition, HNSCC cell lines did not demonstrate cytoplasmic cytochrome c release despite significant mitochondrial membrane depolarization, while HL-60 cell initiated apoptosis and cytochcrome c release after 24 h of treatment. Conclusions: Head and neck cancer cell lines exhibit defects in mitochondrial-membrane-depolarization-induced apoptosis as well as impaired release of cytochrome c despite significant mitochondrial membrane depolarization. Proximal defects in the mitochondrial apoptosis pathway are a feature of HNSCC.(head and neck squamous cell carcinoma)" Note that although the cell lines were depolarized, apoptosis did not occur. So I checked to see if fatty acid metabolism is used by squamous cell carcinoma.

"Today, goldenseal is marketed as a tonic to aid digestion, sooth upset stomach, and as an antibacterial and antiviral agent. It is considered a natural antibiotic and is most often combined with echinacea in preparations designed to strengthen the immune system. Many professional herbalists recommend goldenseal in herbal remedies for hay fever (also called allergic rhinitis), colds, and the flu. Goldenseal is considered a useful antiseptic (which is why some herbalists use it topically to disinfect cuts and scrapes) and astringent. It is commonly used to treat severak skin, eye, and mucous membrane inflammatory and infectious conditions (such as sinusitis, conjunctivitis, and urinary tract infections). It is also available in mouthwashes for sore throats and canker sores. Goldenseal has not been thoroughly investigated in scientific studies, but some trials have looked at berberine, one of the active compounds in goldenseal. Berberine is a substance widely used in Traditional Chinese Medicine to treat dysentery and infectious diarrhea. Berberine may be effective in humans for malaria, heart failure, and various types of infections, including upper respiratory problems."

Mechanisms of berberine (natural yellow 18)-induced mitochondrial dysfunction: interaction with the adenine nucleotide translocator. Pereira CV, Machado NG, Oliveira PJ. Toxicol Sci. 2008 Oct;105(2):408-17. Epub 2008 Jul 3. PMID: 18599498 doi: 10.1124/jpet.107.128017 The data from the present work appear to show that berberine also presents some degree of toxicity to "nontumor" systems, which should be carefully understood. ANT inhibition in nontumor cells by berberine would be responsible for a decrease in energy production and could also result in MPT induction. To the best of our knowledge, no full toxicity assessment exists for berberine in humans, although its use in several commercially available supplements suggests that the compound may present a relatively wide safety interval. In fact, a study with patients with congestive heart failure treated with 1.2 g/day of oral berberine revealed low toxicity and resulted into an average plasma concentration of 0.11 mg/l which would translate into 0.3µM (Zeng and Zeng, 1999Go). Repeated cumulative treatments, alternative forms of formulation (e.g., topical application vs. injection) or more importantly, active mitochondrial accumulation due to its positive charge would be expected to increase its concentration in cells into the range of concentrations used in this study. Empirical data from nontraditional medicines plus the use of extensive clinical assays would allow the use of berberine as a promising antimelanoma agent while maintaining its safety for humans. In radial/vertical forms of melanoma, a possible topical application of berberine would also be possible, thus minimizing side effects on other organs. In conclusion, the present work identifies the ANT as an important target for berberine, with clear relevance for its proposed antitumor effects.

Mangoes are the richest source of most important vitamins (A, C, B, E, K), minerals, dietary fibbers, electrolytes and iron which are mostly required by the for better growth and development as well as being healthy and live life without any diseases and infections. It is liked by all people due to its nice color, taste, flavor and quality health aspects. I have mentioned below the few beneficial aspects of the mangoes which you must know to enhance your interest while eating mangoes: Benefits of Mango juice for Cancer Prevention Mango fruit has antioxidant compounds (such as quercetin, fisetin, astragalin, gallic acid, isoquercitrin, methyl gallate and etc) and lots of enzymes which help in protecting against various body organs cancers like colon, leukemia, breast, stomach, prostate, lungs, cervical, oral cavity cancers and etc. These compounds include, as well as the abundant. Polyphenols found in it acts as an anti inflammatory agent and restricts the growth of cancerous cells. The soluble dietary fibers, pectin found in it has property of decreasing the action of protein (galectin) found in the cancerous cells. Benefits of Mango juice for Heart health It contains highest level of soluble dietary fibers (pectin) and vitamin C which involves in lowering the bad serum cholesterol levels means Low-Density Lipoproteins as well as enhancing the good serum cholesterol levels means High-Density Lipoproteins thus keeps the heart healthy by keeping all the heart problems away. It is the rich source of potassium which involves in controlling the blood pressure thus heart rate. Benefits of Mango juice for Skin It is beneficial for the skin in both ways whether it is eaten or applied externally on the skin. It India juice has antioxidants which make the skin healthy, smooth, glowing and wrinkles free. It clear out the blocked pores and provides solution to get free from the pimples if applied on the face. It makes the skin glowing by reducing the dark spot

Mango Juice is good for Heart Diseases Mangoes contain Beta-carotene, Vitamin E, Potassium and Selenium. All these are effective in making your heart healthy; especially the beta-carotene, which is useful for the cardiac patients. Potassium makes your heart, nerves and muscles to work properly. Mangoes also develop the immune system because vitamin C stimulates White Blood Corpuscles s to work more efficiently thereby destroy the bacteria and germs. Mango Juice reduces the risk of cancer Mangoes contain polyphenol compounds as well as quercetin, isoquercitrin, astragalin, fisetin, gallic acid and methylgallat, all are useful in reducing the risk for different types of cancer. Mango Juice controls blood pressure Mangoes having low glycemic index, that maintains the blood sugar level. It balances the fat levels too. The presence of potassium regulates the blood pressure and fluid mechanism in the body. It also solves the problems of diabetes. Its leaf liquor is good for diabetic patients. Mangoes for glowing & shining skin Mangoes are rich in Vitamin A which makes the skin soft and shining. When the pulp of mango is rubbed over the skin, it makes your complexion fair and maintains the moisture and make the skin glow. Mangoes good for pregnancy Mango is useful fruit for pregnant women as it contain good amount of iron that enables to maintain the HB level and proper oxygen flow. It is suggested that problems during menstruation. Mango relaxes the muscles and prevent abortion due to presence of calcium and magnesium. Mangoes for eyesight The mineral, vitamins and minerals like Vitamin A, C and E are adequately present in Mangoes. It also contains flavonoids, Beta-carotene, alpha-carotene, and beta-cryptoxanthin. All these help to keep your eyes healthy, enhance your vision and prevent from various eye diseases. Mangos aid digestion Mango is full of digestive enzymes like magneferin, katechol oxidase and lactase and helps to overcome the probl

Food And Beverages We are leading Supplier & Distributor for the food and beverages which also includes Mango In Pet Bottle & Mango Juice in Tetra Pack since 2010 Mango Juice Tetra Packs In order to maintain our good will among our valuable patrons, we are actively engaged in manufacturing, exporting and supplying superior quality of COCO Mango Juice Tetra Pack. This tetra pack is highly demanded in the market due to its long lasting freshness, purity and unique flavor. A team of our skilled professionals processed this juice using the best quality of mango and other allied ingredients that are procured form the certified vendors of the industry. Additionally, it can be used for drinking purpose by our patrons in the summer season. Available In: 200 ml 1000 ml Litchi Juice Tetra Packs We are the foremost manufacturer, exporter and supplier of the superior quality of Litchi Juice Tetra Pack that is precisely processed using the quality assured Litchi and modern technology in compliance with the set industry guidelines. Our quality controllers check its quality against varied parameters before delivering it to our esteemed clients. Our offered tetra pack is highly demanded in the market due to its hygienically processed, freshness and long shelf life features. In addition to this, clients can use this tetra pack for the drinking purpose in the summer season. Available In: 200 ml 1000 ml Tetra Juice - 100% fruit Mango Juice contains only the natural ingredients contained in fruit, i.e. fruit juice or fruit juice concentrate, water, natural flavorings and fruit pulp. Whether the juice comes from concentrate or not, it undergoes a mild pasteurization? process before packaging to ensure that the consumer gets a safe, high quality product, without any risk of unwanted micro-organisms. Product content and label-ling of fruit juices are subject to different regulations that vary globally. Mango Juice Tetra Packs supplier & Services Mango Juice In P

Sweetness fruit mango panna juice are a leading Manufacturer & Exporter of fruit squash such as Mango Panna juice from India. Mango Panna juice is an Indian drink renowned for its heat resistant properties. It is made from green mangoes and it is used as a tasty and healthy beverage to fight against the intense Indian summer heat. Apart from being tasty drink also looks good due to its refreshing light green colour. Green Mango is a rich source of pectin, which gradually diminishes after the formation of the stone. Unripe mango juice is sour in taste because of the presence of oxalic, citric and malic acids. mango panna juice which is prepared using raw mangoes, sugar and an assortment of spices is an effective remedy for heat exhaustion and heat stroke. It also quenches thirst and prevents the excessive loss of sodium chloride and iron during summer due to excessive sweating. This drink is also a good source of vitamin B1 and B2 and contains sufficient quantity of niacin, and since it is prepared from raw mangoes it is an excellent source of vitamin C also. Aam Panna is also considered as a curative for blood disorders because of its high vitamin C content. Mango panna juice Owing to year of experience in this domain, we are engaged in providing best quality of Mango Panna juice. It is processed using green mangoes and it is used as a tasty and healthy beverage. Further, these products are available in market at pocket friendly prices and known for their rich taste. Our products are of premium quality. Some health benefits of panna mango juice: 1.It prevents you from heat stroke and keeps the body cool. 2.Raw mangoes are rich in vitamin c and iron, plus the jaggery also gives an iron boost. 3.The aam panna helps in preventing stomach problems in the summers. panna juice are three indian drinks i often make in the summers are shikanji, mango panna juice and Mango drink. they all are summer

If the adage "eat her appointment" is true, it has the opposite effect if you eat food is not hygienic. Finally you will bear all bacteria, fungi, mold Map ... will slowly go into your body. And of course with the naked eye can not see the dirty things in food that contains the seeds and they will cause disease. It's time you need to know what good preservation of food for your family. When shopping - Always look carefully "limited use" (best before) and the time of production date on the box of food. - Never buy the box was open, convex and concave or leak. - Reading in food color, deep, or adhesives that are fresh or not oily. - Open the box to check for eggs is definitely not broken or dirty eggs. - Require vendors to use two or more bags containing meat, fish so they will not dirty water flowing from other foods. - Should go straight home after checkout is completed. Otherwise the food will be damaged (run) and it is an opportunity for bacteria arise. In the kitchen Refrigerator: - Adjust the temperature from 4 º C (39.2 º F) or lower. - Always keep the refrigerator clean. - Arrange the items, but not too tight to open cold air transmission to the proper temperature for food preservation is best. - When you want to melt the ice, you should keep the packaging for meat, fish and placed on disk so they do not leak through other foods. Absolutely not use the microwave oven (microwave) to melt the ice. - Keep raw egg placed in a refrigerator box to warm temperatures is not easy to damage the eggs. - Put food place. Vegetables, fruits and ready-made food is always placed in the last compartment - Do not place or potatoes in the refrigerator. - Do not wash, or marinating food prior to refrigeration. Should only be washed before eating or cooking. - Food for the external balance should not exceed 2 hours or contain no more than 2 days in refrigerator. Freezer co

Statins and vitamin D. Aloia JF, Li-Ng M, Pollack S. Am J Cardiol. 2007 Oct 15;100(8):1329. Epub 2007 Jul 5. No abstract available. PMID: 17920383 A total of 208 women were randomized to receive vitamin D3 (n=104) or placebo (n=104). 51 women were on statins. At baseline, the subjects on statins had a significantly higher 25-OHD level than the subjects who were not on statins (51.2 ± 20.1 nmol/L versus 43.2 ± 18.0 nmol/L respectively, p=0.008). This was also true when averaging 25-OHD levels across the 3-year study period and looking at active and placebo patients separately. 185 subjects had follow-up 25-OHD levels drawn every 6 months during the study. Higher levels were seen in the statin use subgroup whether they were on placebo or active vitamin D (Figure 1Figure 1). There was no interaction seen between vitamin D use and statin use, i.e. the impacts are additive (p=0.5502). This significant difference is comparable to the increase in 25-OHD levels seen in Pérez-Castrillón's study (41 ± 19 versus 47 ± 19 nmol/L, p=0.003) [1]. Although Pérez-Castrillón et al found a statistically significant relation between total cholesterol and 25-OHD (r=0.277, p=0.002), we did not find a significant relation between total cholesterol and 25-OHD in our study population.

Beta Glucan is primarily cultured extract of Baker's Yeast cell wall. It is used as an immunostimulant.  Beta glucans are sugar molecules (polysaccharides). They are found bound together as a sugar/protein complex.  Certain plants and microorganisms are naturally high in this polysaccharide compound.  The richest concentrated source is baker's yeast cell walls. (Because there is basically no yeast left in the products and they have low protein levels, it is considered hypoallergenic.) It is present in lesser amounts in mushroom extracts and Lentinen, Barley, Oat, etc. Sodium alginate is also an excellent source, but the high sodium content is a major drawback in the processing for supplemental use. An expensive research extract called Zymosan™ has been used for doing research for over 45 years. Much of the research has been in combining it with conventional approaches, such as chemotherapy, but it has been found to work well on its own.

Clinical Implications of JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a U.S. Population Insights From the ARIC (Atherosclerosis Risk in Communities) Study Yang EY et al. J Am Coll Cardiol, 2009; 54:2388-2395, doi:10.1016/j.jacc.2009.10.006 Conclusions: ARIC participants with elevated hs-CRP and low LDL-C had a CVD event rate of 1.57% per year over 6.9 years, similar to the CVD event rate noted in the JUPITER study placebo group (1.36% per year over 1.9 years). The association of hs-CRP ≥2.0 mg/l with increased CVD risk and mortality regardless of LDL-C provides us a simple method of using age and hs-CRP level for identifying higher risk individuals. (Atherosclerosis Risk in Communities study; NCT00005131)

Berberine and Coptidis rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations. Tang J, Feng Y, Tsao S, Wang N, Curtain R, Wang Y. J Ethnopharmacol. 2009 Oct 29;126(1):5-17. Epub 2009 Aug 15. PMID: 19686830 doi:10.1016/j.jep.2009.08.009 Conclusions The modern evidences of treating cancer with Huanglian and berberine have a strong linkage with traditional concept and rules of using Huanglian in CM practice. As anticancer candidates with low toxicity, berberine and its altered structure, as well as Huanglian and its formulae, will attract scientists to pursue the potential anticancer effects and the mechanisms by using technologies of genomics, proteomics and other advanced approaches. On the other hand, relatively few in vivo studies have been conducted on anticancer effects of Huanglian and berberine. The clinical application of berberine or Huanglian as novel cancer therapeutic agents requires in vivo validations and further investigations of their anticancer mechanisms.

The amount of energy to be provided by a balanced diet for any person will depend on several factors: age, sex, body size, lifestyle, occupation, and the climate of the area he is in. The proportion of the various food classes in a diet is also not the same for different persons, due to varying physical and physiological requirements..

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3 Winter-Friendly Murabbas That Will Add the Right Sweetness to Your Diet Winter is the perfect time to enjoy tasty Murabbas to one's heart's content. The plummeting temperatures and crisp air announce the arrival of winter. This season is mostly about soaking in the afternoon sun or munching on seasonal foods.The freshness of veggies and fruits you get this season is incomparable. So, to add to the fun, it makes sense to make delicious Murabbas out of these seasonal fruits that could be a treat to your taste buds. https://gongloofoods.blogspot.com/2023/01/3-winter-friendly-murabbas-that-will.html