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"Also known as Lycium barbarum fruit, goji berry grows on a bush and is native to northwestern China. The oblong-shaped berries are bright red and contain 20-40 tiny seeds, and can be eaten raw, or made into a juice or wine, brewed for tea, or prepared as a tincture. But it's the extracted phytochemicals used in nutritional supplements that provide the most potent health benefits. Goji berry has been used in Traditional Chinese Medicine (TCM) for thousands of years as a health tonic to promote overall health and healthy eyesight, strengthen the immune system, protect the liver, improve circulation and sperm production, and to enhance sexual performance. It has also been used as a remedy for diabetes, anemia, tinnitus, and lung diseases."

A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs. Sun Y, Xun K, Wang Y, Chen X. Anticancer Drugs. 2009 Oct;20(9):757-69. PMID: 19704371

Traditional chinese medicine in treatment of metabolic syndrome. Yin J, Zhang H, Ye J. Endocr Metab Immune Disord Drug Targets. 2008 Jun;8(2):99-111. Review. PMID: 18537696 Berberine from rhizoma coptidis is an oral hypoglycemic agent. It also has anti-obesity and anti-dyslipidemia activities. The action mechanism is related to inhibition of mitochondrial function, stimulation of glycolysis, activation of AMPK pathway, suppression of adipogenesis and induction of low-density lipoprotein (LDL) receptor expression.

Berberine and Coptidis rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations. Tang J, Feng Y, Tsao S, Wang N, Curtain R, Wang Y. J Ethnopharmacol. 2009 Oct 29;126(1):5-17. Epub 2009 Aug 15. PMID: 19686830 doi:10.1016/j.jep.2009.08.009 Conclusions The modern evidences of treating cancer with Huanglian and berberine have a strong linkage with traditional concept and rules of using Huanglian in CM practice. As anticancer candidates with low toxicity, berberine and its altered structure, as well as Huanglian and its formulae, will attract scientists to pursue the potential anticancer effects and the mechanisms by using technologies of genomics, proteomics and other advanced approaches. On the other hand, relatively few in vivo studies have been conducted on anticancer effects of Huanglian and berberine. The clinical application of berberine or Huanglian as novel cancer therapeutic agents requires in vivo validations and further investigations of their anticancer mechanisms.