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The effects of conjugated linoleic acid on human health-related outcomes. Tricon S, Burdge GC, Williams CM, Calder PC, Yaqoob P. Proc Nutr Soc. 2005 May;64(2):171-82. Review. PMID: 15960862 Conjugated linoleic acid (CLA) is a collective term for a mixture of positional and geometric isomers of conjugated dienoic derivatives of linoleic acid. CLA has received considerable attention as a result of animal experiments that report anti-carcinogenic, anti-atherogenic and anti-diabetic properties, and modulation of body composition and immune function. Several studies of CLA supplementation in human subjects have now been published, but in contrast to animal studies there has been marked variation between reports on the health-related outcomes. The consensus from seventeen published studies in human subjects is that CLA does not affect body weight or body composition. Some detrimental effects of the trans-10,cis-12 CLA isomer have also been reported in terms of altered blood lipid composition and impaired insulin sensitivity. Finally, CLA has only limited effects on immune functions in man. However, there have been reports of some interesting isomer-specific effects of CLA on the blood lipid profile, but not on immune function. These isomer-specific effects need further investigation. Until more is known, CLA supplementation in man should be considered with caution.

Mechanisms of berberine (natural yellow 18)-induced mitochondrial dysfunction: interaction with the adenine nucleotide translocator. Pereira CV, Machado NG, Oliveira PJ. Toxicol Sci. 2008 Oct;105(2):408-17. Epub 2008 Jul 3. PMID: 18599498 doi: 10.1124/jpet.107.128017 The data from the present work appear to show that berberine also presents some degree of toxicity to "nontumor" systems, which should be carefully understood. ANT inhibition in nontumor cells by berberine would be responsible for a decrease in energy production and could also result in MPT induction. To the best of our knowledge, no full toxicity assessment exists for berberine in humans, although its use in several commercially available supplements suggests that the compound may present a relatively wide safety interval. In fact, a study with patients with congestive heart failure treated with 1.2 g/day of oral berberine revealed low toxicity and resulted into an average plasma concentration of 0.11 mg/l which would translate into 0.3µM (Zeng and Zeng, 1999Go). Repeated cumulative treatments, alternative forms of formulation (e.g., topical application vs. injection) or more importantly, active mitochondrial accumulation due to its positive charge would be expected to increase its concentration in cells into the range of concentrations used in this study. Empirical data from nontraditional medicines plus the use of extensive clinical assays would allow the use of berberine as a promising antimelanoma agent while maintaining its safety for humans. In radial/vertical forms of melanoma, a possible topical application of berberine would also be possible, thus minimizing side effects on other organs. In conclusion, the present work identifies the ANT as an important target for berberine, with clear relevance for its proposed antitumor effects.

Egg consumption in relation to cardiovascular disease and mortality: the Physicians' Health Study. Djoussé L, Gaziano JM. Am J Clin Nutr. 2008 Apr;87(4):964-9. PMID: 18400720 Results: In an average follow-up of 20 y, 1550 new myocardial infarctions (MIs), 1342 incident strokes, and 5169 deaths occurred. Egg consumption was not associated with incident MI or stroke in a multivariate Cox regression. In contrast, adjusted hazard ratios (95% CI) for mortality were 1.0 (reference), 0.94 (0.87, 1.02), 1.03 (0.95, 1.11), 1.05 (0.93, 1.19), and 1.23 (1.11, 1.36) for the consumption of < 0.0001). This association was stronger among diabetic subjects, in whom the risk of death in a comparison of the highest with the lowest category of egg consumption was twofold (hazard ratio: 2.01; 95% CI: 1.26, 3.20; P for interaction = 0.09). Conclusions: Infrequent egg consumption does not seem to influence the risk of CVD in male physicians. In addition, egg consumption was positively related to mortality, more strongly so in diabetic subjects, in the study population.

The best way to give up smoking is also by concentrating on the positive effects it may show up on your health. A smoker always starts the quitting smoking process by a negative thought. This is absolutely wrong as the one negative thought will attract the other negative thought as per the "Like attract likes" theory and there will be no improvement in a smoker's condition

Refurbished B. Braun Horizon NXT Infusion IV Pump The Refurbished B. Braun Horizon NXT Infusion IV Pump is intended for use with B. Braun Horizon I.V. sets to regulate the flow of primary and secondary fluids when positive pressure is required. The infusion system features the capability of delivering fluid from a negative head height, and provides volumetric accuracy for all standard I.V. fluids, including blood, lipids and TPN.

Refurbished B. Braun Horizon NXT Infusion IV Pump The Refurbished B. Braun Horizon NXT Infusion IV Pump is intended for use with B. Braun Horizon I.V. sets to regulate the flow of primary and secondary fluids when positive pressure is required. The infusion system features the capability of delivering fluid from a negative head height, and provides volumetric accuracy for all standard I.V. fluids, including blood, lipids and TPN.

Refurbished B. Braun Horizon NXT Infusion IV Pump The Refurbished B. Braun Horizon NXT Infusion IV Pump is intended for use with B. Braun Horizon I.V. sets to regulate the flow of primary and secondary fluids when positive pressure is required. The infusion system features the capability of delivering fluid from a negative head height, and provides volumetric accuracy for all standard I.V. fluids, including blood, lipids and TPN.

Cancer Prevention and Heart Health Mango Juice have high amounts of pectin, a soluble dietary fiber that efficiently contributes to lower cholesterol levels in the blood. Pectin can also help prevent you from developing prostate cancer. Recently, studies at The Institute for Food Research discovered that a compound within pectin combines with galectin 3 (a protein playing significant role in all the stages of cancer). The European Prospective Investigation of Cancer also has come up with a strong association between eating mango and lowering the risk of cancers of the gastrointestinal tract. Diabetes Management and Prevention Further Mango Juice research is still ongoing, but some studies have already revealed that mango Juice are a great natural remedy for diabetes. It was a long-told myth that diabetic patients should avoid Mango Drinks because of its sweet taste; now it is being shown that other than the fruit, the mango leaves are also helpful in curing diabetes. Place 10 or 15 mango leaves in warm water and close it with a lid before going to bed. In the morning, drink the water on an empty stomach after filtering the leaves. Regular practice of this method has shown positive results for diabetic patients in the management of their blood sugar levels. Weight Gain Mango juice consumption is one of the easiest ways to gain weight. 150g of mango has around 86 calories, which can be absorbed easily by the body. Moreover, mangoes contain starch, which transforms into sugar that aids in gaining weight. Some people work hard to put on weight for a variety of reasons, and mango should definitely be a part of their diet. Mango milkshakes will accelerate the process of gaining weight since they also contain milk, and are notoriously delicious! Aids Digestion Mango Juice play a prominent role in eliminating problems such as indigestion and excess acidity. The digestive enzymes in mango juice help to promote natural, efficient digestion. The bioactive ingredie

Good remedy for diabetes Diabetes is not a condition that one can ignore or consider trivial. The condition is essentially a disorder that is characterized by excess amounts of blood sugar leading to serious medical complications such as damaged blood vessels. Some of the more common causes of diabetes include: high cholesterol, hereditary, insulin resistance and high blood pressure. There are three main types of diabetes type 1 diabetes, type 2 diabetes and gestational diabetes in pregnant women. In order to control the blood sugar levels properly, one needs to be careful of the different kinds of sugar ingested meaning that a number of sweet foods will have to be avoided. When discussing about diet for diabetics, most people wonder if mangos for diabetics are safe. Mango juice still Leaves For Diabetes One of the best natural treatments is to use mango leaves for diabetes. You just need to boil about three or four mango leaves and drink the water. The benefits of mango leaves for blood sugar have been ascertained after lot of research. The research substantiates that the medicinal properties contribute to the lowering of the blood sugar levels within the body. For better results, you should try soaking the leaves over the course of the night in water and consume the solution early the next morning. Ensure that you consume the solution on an empty stomach first thing in the morning. Mango Juice Diabetes Prevention and Management Further Mango juice research is still ongoing, but some studies have already revealed that mangoes are a great natural remedy for diabetes. It was a long-told myth that diabetic patients should avoid mangoes because of its sweet taste; now it is being shown that other than the fruit, the mango leaves are also helpful in curing diabetes. Place 10 or 15 mango leaves in warm water and close it with a lid before going to bed. In the morning, drink the water on an empty stomach after filtering the leaves. Regular practice of this meth

Mango is one of the delicious tropical seasonal fruit and believed to be originated in the sub-Himalayan plains of Indian subcontinent.It is Maintains cancers, Blood Pressure and heart conditions and more.

Mango juice contains the vital nutrient, potassium that assists your muscles, heart and nerves' functions. This advantageous mineral also regulates the balance of fluids in your body and your blood pressure.

Mangoes is a seasonal fruit has been a regular part of human diet for about four thousand years, thanks to its unique flavour, taste and fragrance. You would also have relished this fruit but do you know the benefits of mango?

Mangoes have an impressive vitamin content that assures overall health. They are rich in potassium (4% in 156 mg) and magnesium (2% in 9 mg), and mango juice are great natural remedies for high blood pressure patients. They also contain selenium, calcium, iron and phosphorus. Mangoes are said to be vitamin powerhouses as they are rich in riboflavin, vitamin B6, A, C, E, K, niacin, folate, thiamin and panthothenic acid. These components help you to avoid a host of diseases that can come from deficiencies of these vitamins and minerals. The vitamin E content in mangoes can even help to boost your sex life by triggering the activity of your sex hormones.

Research and studies published at Comprehensive Reviews in Food Science and Food Safety have demonstrated that dietary fiber has a positive effect on eliminating degenerative diseases, including certain cancers,Blood Pressure and heart conditions. Now you have even more reasons to include this delicious fruit in your daily diet. The more you participate in strenuous activities,the more bodily potassium you lose, which is yet another helpful side effects of mangoes - high potassium content!

MS Dhoni movie, constricted screenplay and good presentations make this one a great watch. Director: Neeraj Pandey Cast: Sushant Singh Rajput, Kiara Advani, Disha Patani, Bhumika Chawla, Ram Charan, Herry Tangri Once a director chooses to pick a topic like MS Dhoni, it is positively a very big duty. The fabulous cricketer has proved to the world ...

Do your joints creak while engaging in a simple physical activity? Do you wake up with stiffness in joints accompanied by excruciating pain? If so, you may be suffering from a chronic joint and muscle condition. But you are not alone. Over 50% of Indians face joint and muscle issues as early as in their 30s. While a sedentary lifestyle is a major culprit, poor eating habits may also play into making the condition worse. In some cases, elevated Vata doshas can also lead to inflammation in joints, which becomes a chronic condition if not addressed and treated in time. GT Capsules is an effective Ayurvedic medicine for joint and muscle pain, formulated with anti-inflammatory and antirheumatic herbs that have been an important part of the Ayurveda medicine system for thousands of years. GT Capsule is a blend of herbs like Bruhati, Nimba, Guduchi, Guggulu and Patola. Apart from treating joint and muscle problems, these capsules can be an effective remedy for skin diseases, like eczema and psoriasis. Combined with a healthy lifestyle and positive dietary changes, GT Capsules can help you find relief from muscle and joint issues in as little as two weeks.

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Excess weight is not a problem any more for a lot of people. These people have been fat for years or for decades and they have accepted this state as a part of their miserable lives. They have tried numerous weight loss programs which had no positive results. Now they think that there is something wrong with them and losing weight is impossible for them. But this is not true. They are probably victims of unscrupulous traders who sell such weight loss products that don't deliver the promised results. These traders don't want to give real solutions, there is one thing that they want: lots of money - at whatever cost. They take advantage of the people's desperation. ....Lose Weight Naturally And For Free