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Matti Narkia

Vitamin D May Be Tied to Heart Disease Via Genes - Heart Disease and Other Cardiovascul... - 0 views

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    "THURSDAY, Dec. 3 (HealthDay News) -- New research points to the possibility of a genetic link between vitamin D and heart disease.

    People with high blood pressure who had a gene variant that reduces vitamin D activation in the body were found to be twice as likely as those without the variant to have congestive heart failure, the study found.

    The finding may lead to a way to identify people at increased risk for heart disease, according to Robert U. Simpson, an assistant professor of pharmacology at the University of Michigan Medical School and his research colleagues.

    They analyzed the genetic profiles of 617 people. One-third had hypertension, one-third had hypertension and congestive heart failure, and the remaining third served as healthy controls.

    The researchers found that a variant in the CYP27B1 gene was associated with congestive heart failure in people with hypertension. The study is in the November issue of Pharmacogenomics."
Matti Narkia

Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids - Journal... - 0 views

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    Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids.
    Berquin IM, Min Y, Wu R, Wu J, Perry D, Cline JM, Thomas MJ, Thornburg T, Kulik G, Smith A, Edwards IJ, D'Agostino R, Zhang H, Wu H, Kang JX, Chen YQ.
    J Clin Invest. 2007 Jul;117(7):1866-75.
    PMID: 17607361

    Our data suggest that modulation of prostate cancer development by polyunsaturated fatty acids is mediated in part through Bad-dependent apoptosis. This study highlights the importance of gene-diet interactions in prostate cancer.
Matti Narkia

Association study on two vitamin D receptor gene polymorphisms and vitamin D metabolite... - 0 views

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    Association study on two vitamin D receptor gene polymorphisms and vitamin D metabolites in multiple sclerosis.
    Smolders J, Damoiseaux J, Menheere P, Tervaert JW, Hupperts R.
    Ann N Y Acad Sci. 2009 Sep;1173:515-20.
    PMID: 19758194
    DOI: 10.1111/j.1749-6632.2009.04656.x

    Discussion: We found no association of the Apal and Taql VDR gene SNPs with MS or with vitamin D metabolism in our population. Further research should assess the complex interaction between vitamin D, the VDR, and susceptibility to MS.
Matti Narkia

The quest for cardiovascular health in the genomic era: nutrigenetics and plasma lipopr... - 0 views

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    Ordovas JM.
    The quest for cardiovascular health in the genomic era: nutrigenetics and plasma lipoproteins.
    Proc Nutr Soc. 2004 Feb;63(1):145-52. Review.
    PMID: 15070444 [PubMed - indexed for MEDLINE]
Matti Narkia

Genetic interactions with diet influence the risk of cardiovascular disease -- Ordovas ... - 0 views

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    Ordovas JM.
    Genetic interactions with diet influence the risk of cardiovascular disease.
    Am J Clin Nutr. 2006 Feb;83(2):443S-446S. Review.
    PMID: 16470010 [PubMed - indexed for MEDLINE]
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