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World Vitamins

When Should I Get Medical Care For a Person With Diabetes? - 2 views

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    f you or anyone you know are experiencing symptoms of diabetes it is important to seek medical care. This is true even if the person is not known to be diabetic. When making the appointment tell them that you are concerned with diabetes.
World Vitamins

Too Many Infants Short on Vitamin D « World Vitamins Online - 2 views

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    Most infants in the United States aren't getting enough vitamin D and should be given supplements, a new federal government report shows.
Matti Narkia

MedWire News - Diabetes - Very low HbA1c values may be as harmful as very high values - 2 views

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    "Lancet 2010; Advance online publication

    MedWire News: There is a U-shaped relationship between glycated hemoglobin (HbA1c) levels and mortality in people with diabetes, say researchers, meaning that intensive glucose-lowering therapy could be as harmful as uncontrolled hyperglycemia.

    Writing in The Lancet, Craig Currie (Cardiff University, UK) and team say that if their findings are confirmed then diabetes guidelines may need to be revised to include a lower as well as an upper HbA1c threshold.

    Currie's team used the UK General Practice Research Database from November 1986 to November 2008 to obtain data on two cohorts of patients aged 50 years and older with Type 2 diabetes.

    The patients comprised 27,965 individuals whose treatment had been intensified from oral monotherapy to combination therapy with oral blood-glucose lowering agents, and 20,005 who had changed to insulin-containing regimens."
Matti Narkia

Sugar May Be Bad, But This Sweetener Is Far More Deadly, Part 1 of 3 - 4 views

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    "Scientists have proved for the first time that fructose, a cheap form of sugar used in thousands of food products and soft drinks, can damage human metabolism and is fueling the obesity crisis.

    Fructose, a sweetener usually derived from corn, can cause dangerous growths of fat cells around vital organs and is able to trigger the early stages of diabetes and heart disease.

    Over 10 weeks, 16 volunteers on a controlled diet including high levels of fructose produced new fat cells around their heart, liver and other digestive organs. They also showed signs of food-processing abnormalities linked to diabetes and heart disease. Another group of volunteers on the same diet, but with glucose sugar replacing fructose, did not have these problems."
Matti Narkia

Nutritional diseases - modern-diets-and-nutritional-diseases.com - 0 views

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    "What Are Nutritional Diseases?

    In their book, The Modern Nutritional Diseases, Fred and Alice Ottoboni, retired Public Health Service scientists, list the following.
    * Obesity
    * Diabetes II
    * Cardiovascular Diseases
    * Stroke.
    * Cancer.

    Modern nutritional diseases are just that. They haven't always been the ugly part of our life. They were introduced when people had to get their food from grocery stores, when people traded their whole foods from the family farm for those manufactured by the food processing industry. "
Matti Narkia

Unexpected Perks of Coffee Consumption - The Early Show - CBS News - 0 views

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    "(CBS) Your daily cup of java may deliver some unexpected health benefits. Studies have shown it may lower your risk for Type II diabetes and certain types of cancer (colon, mouth and throat), and protect against heart disease and cavities.

    Dr. Alanna Levine, a primary care physician, said on "The Early Show" researchers aren't sure exactly why coffee has these benefits, but speculated that perhaps the coffee has antioxidant properties. "
Matti Narkia

Overview and perspective in human nutrition. Willett WC. - Asia Pac J Clin Nutr. 2008; - 0 views

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    Overview and perspective in human nutrition.
    Willett WC.
    Asia Pac J Clin Nutr. 2008;17 Suppl 1:1-4. Review.
    PMID: 18296289

    For the last decade, the focus of nutritional advice for prevention of chronic disease has been to limit or reduce
    total fat intake and to consume large amounts of carbohydrate. However, this advice is inconsistent with many
    lines of evidence indicating that unsaturated fats have beneficial metabolic effects and reduce risk of coronary
    heart disease. More recent evidence has also shown that the large majority of carbohydrates in Western diets,
    consisting of refined starches and sugars, have adverse metabolic effects and increase risks of coronary heart
    disease and type 2 diabetes. Unfortunately, a major opportunity for health improvement has been lost by failing
    to distinguish healthy from unhealthy forms of carbohydrates and fats. Recent analyses indicate that moderate
    changes in diet, together with regular physical activity and not smoking, can prevent the large majority of heart
    disease, type 2 diabetes, and some forms of cancer. These findings have substantial relevance for many populations
    in Asia, where incidence of type 2 diabetes is rising rapidly.
Matti Narkia

Coffee, Tea May Stall Diabetes - Diabetes Mellitus, Type 2 Diabetes, Type 1, and Metabo... - 2 views

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    "Dec. 14, 2009 -- Every cup of coffee a person drinks per day may lower the risk of diabetes by 7%.

    A new review of research on the link between lifestyle factors, like coffee and tea consumption, and diabetes risk suggests that drinking regular or decaffeinated coffee and tea all lower the risk of type 2 diabetes.

    Researchers say the number of people with type 2 diabetes is expected to increase by 65% by 2025, reaching an estimated 380 million people worldwide.

    "Despite considerable research attention, the role of specific dietary and lifestyle factors remains uncertain, although obesity and physical inactivity have consistently been reported to raise the risk of diabetes mellitus," write researcher Rachel Huxley, DPhil, of the George Institute for International Health, University of Sydney, Australia, and colleagues in the Archives of Internal Medicine.

    They say several studies have suggested that drinking coffee may lower the risk of developing type 2 diabetes and others have shown that decaffeinated coffee and tea may offer similar benefits, but there has not been a recent review of the research on the issue."
Matti Narkia

Coffee, Decaffeinated Coffee, and Tea Consumption in Relation to Incident Type 2 Diabet... - 0 views

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    Coffee, decaffeinated coffee, and tea consumption in relation to incident type 2 diabetes mellitus: A systematic review with meta-analysis.
    Huxley R, Lee CM, Barzi F, Timmermeister L, Czernichow S, Perkovic V, Grobbee DE, Batty D, Woodward M.
    Arch Intern Med. 2009 Dec 14;169(22):2053-63.
    PMID: 20008687

    Conclusions Owing to the presence of small-study bias, our results may represent an overestimate of the true magnitude of the association. Similar significant and inverse associations were observed with decaffeinated coffee and tea and risk of incident diabetes. High intakes of coffee, decaffeinated coffee, and tea are associated with reduced risk of diabetes. The putative protective effects of these beverages warrant further investigation in randomized trials.
Matti Narkia

Quality of HDL differs in diabetics but improves with niacin therapy - theheart.org - 1 views

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    "Quality of HDL differs in diabetics but improves with niacin therapy
    December 22, 2009 | Michael O'Riordan

    Hannover, Germany - A small study published this week hints that the effects of HDL cholesterol differ in healthy patients from those with diabetes mellitus [1]. HDL cholesterol in individuals with diabetes has impaired endothelial protective functions compared with the HDL from healthy subjects, although treatment with extended-release niacin can improve these endothelial protective effects, according to researchers.

    Publishing their findings online December 21, 2009 in Circulation, lead investigator Dr Sajoscha Sorrentino (Hannover Medical School, Germany) and colleagues write that because recent HDL-raising intervention studies have yielded mixed results, "circulating HDL-cholesterol levels alone likely do not represent an adequate measure of therapeutic efficacy, and indexes of HDL functionality are urgently needed for assessment of the potential of HDL-targeted therapies to exert vasoprotective effects."

    Speaking with heartwire, senior investigator Dr Ulf Landmesser (University of Zürich, Switzerland), said the results have implications for clinical research.

    "We have to understand that we can't look only at the HDL levels in the plasma, but we need to look at the quality," he said. "The quality of the HDL is not the same in different patients. This is very important for targeting HDL as a treatment. Second, niacin therapy is a promising way not only to raise HDL but also to improve the quality; it is a good treatment option, especially if the larger outcomes data are positive.""
Matti Narkia

Endothelial-Vasoprotective Effects of High-Density Lipoprotein Are Impaired in Patients... - 0 views

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    Endothelial-Vasoprotective Effects of High-Density Lipoprotein Are Impaired in Patients With Type 2 Diabetes Mellitus but Are Improved After Extended-Release Niacin Therapy.
    Sorrentino SA, Besler C, Rohrer L, Meyer M, Heinrich K, Bahlmann FH, Mueller M, Horváth T, Doerries C, Heinemann M, Flemmer S, Markowski A, Manes C, Bahr MJ, Haller H, von Eckardstein A, Drexler H, Landmesser U.
    Circulation. 2009 Dec 21. [Epub ahead of print]
    PMID: 20026785
    doi: 10.1161/CIRCULATIONAHA.108.836346

    Conclusions-HDL from patients with type 2 diabetes mellitus and metabolic syndrome has substantially impaired endothelial-protective effects compared with HDL from healthy subjects. ER niacin therapy not only increases HDL plasma levels but markedly improves endothelial-protective functions of HDL in these patients, which is potentially more important.
Matti Narkia

NEJM -- Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reacti... - 0 views

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    Conclusions In this trial of apparently healthy persons without hyperlipidemia but with elevated high-sensitivity C-reactive protein levels, rosuvastatin significantly reduced the incidence of major cardiovascular events. \n\nRosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.\nRidker PM, Danielson E, Fonseca FA, Genest J, Gotto AM Jr, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ; JUPITER Study Group.\nN Engl J Med. 2008 Nov 20;359(21):2195-207. Epub 2008 Nov 9.\nPMID: 18997196
Matti Narkia

Vitamin D and calcium insufficiency-related chronic diseases: molecular and cellular pa... - 0 views

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    Vitamin D and calcium insufficiency-related chronic diseases: molecular and cellular pathophysiology.
    Peterlik M, Cross HS.
    Eur J Clin Nutr. 2009 Dec;63(12):1377-86. Epub 2009 Sep 2.
    PMID: 19724293
    doi:10.1038/ejcn.2009.105

    A compromised vitamin D status, characterized by low 25-hydroxyvitamin D (25-(OH)D) serum levels, and a nutritional calcium deficit are widely encountered in European and North American countries, independent of age or gender. Both conditions are linked to the pathogenesis of many degenerative, malignant, inflammatory and metabolic diseases. Studies on tissue-specific expression and activity of vitamin D metabolizing enzymes, 25-(OH)D-1alpha-hydroxylase and 25-(OH)D-24-hydroxylase, and of the extracellular calcium-sensing receptor (CaR) have led to the understanding of how, in non-renal tissues and cellular systems, locally produced 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3) and extracellular Ca2+ act jointly as key regulators of cellular proliferation, differentiation and function. Impairment of cooperative signalling from the 1,25-(OH)2D3-activated vitamin D receptor (VDR) and from the CaR in vitamin D and calcium insufficiency causes cellular dysfunction in many organs and biological systems, and, therefore, increases the risk of diseases, particularly of osteoporosis, colorectal and breast cancer, inflammatory bowel disease, insulin-dependent diabetes mellitus type I, metabolic syndrome, diabetes mellitus type II, hypertension and cardiovascular disease. Understanding the underlying molecular and cellular processes provides a rationale for advocating adequate intake of vitamin D and calcium in all populations, thereby preventing many chronic diseases worldwide.
Matti Narkia

Vitamin D may curb diabetes - Pharmacy News - 0 views

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    A New Zealand study has found that South Asian women with insulin resistance improved markedly after taking vitamin D supplements

    Nutrition researcher Pamela von Hurst of the Institute of Food, Nutrition and Human Health at Albany, said while diet and exercise played a major part in the onset of type-2 diabetes, her findings reinforced the importance of vitamin D from the sun and supplements to prevent type-2 diabetes.

    Initial screening of 235 Auckland women from India, Pakistan and Sri Lanka aged 20 and older, revealed 47 per cent were insulin deficient and 84 per cent were vitamin D deficient. The 81 recruited for the study were split into two groups for a randomised controlled trial and given a vitamin D supplement or placebo. As well as an improvement in insulin resistance among those who took vitamin D for six months, Ms Von Hurst said post-menopausal women in the study also showed a reduced rate of bone breakdown.
Matti Narkia

Pine bark extract may boost diabetic eye health - 0 views

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    "Supplements of French maritime pine bark extract may improve the flow of blood in the tiny blood vessels of the retina, and enhance sight in diabetics with early stage eye problems, says a new study.

    Visual acuity, or the clearness of vision, was found to improve from 14/20 to 17/20 in people with early stage retina damage associated with diabetes (diabetic retinopathy) following daily supplements of the pine bark extract, Pycnogenol, for two months.

    Forty-six diabetics participated in the randomised controlled study with the findings published in the Journal of Ocular Pharmacology and Therapeutics.

    "Our study suggests that Pycnogenol taken in the early stages of retinopathy may enhance retinal blood circulation accompanied by a regression of oedema, which favourably improves vision of patients," said lead researcher Dr Robert Steigerwalt. "Pycnogenol may be particularly beneficial for preventing this complication in diabetic patients, based on the large number of individuals who were diagnosed when the disease had already significantly progressed"
Matti Narkia

Drinking coffee, decaf and tea regularly associated with a reduced risk of diabetes - 0 views

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    "Rachel Huxley, D.Phil, of The George Institute for International Health, University of Sydney, Australia, and colleagues identified 18 studies involving 457,922 participants and assessing the association between coffee consumption and diabetes risk published between 1966 and 2009.

    Six studies involving 225,516 individuals also included information about decaffeinated coffee, whereas seven studies with 286,701 participants reported on tea consumption.

    When the authors combined and analyzed the data, they found that each additional cup of coffee consumed in a day was associated with a 7 percent reduction in the excess risk of diabetes.

    Individuals who drank three to four cups per day had an approximately 25 percent lower risk than those who drank between zero and two cups per day.

    Rachel Huxley, D.Phil, of The George Institute for International Health, University of Sydney, Australia, and colleagues identified 18 studies involving 457,922 participants and assessing the association between coffee consumption and diabetes risk published between 1966 and 2009.

    Six studies involving 225,516 individuals also included information about decaffeinated coffee, whereas seven studies with 286,701 participants reported on tea consumption.

    When the authors combined and analyzed the data, they found that each additional cup of coffee consumed in a day was associated with a 7 percent reduction in the excess risk of diabetes.

    Individuals who drank three to four cups per day had an approximately 25 percent lower risk than those who drank between zero and two cups per day."
Matti Narkia

Fish intake is associated with a reduced progression of coronary artery ather... - 0 views

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    Fish intake is associated with a reduced progression of coronary artery atherosclerosis in postmenopausal women with coronary artery disease.
    Erkkilä AT, Lichtenstein AH, Mozaffarian D, Herrington DM.
    Am J Clin Nutr. 2004 Sep;80(3):626-32.
    PMID: 15321802

    Conclusions: Consumption of fish is associated with a significantly reduced progression of coronary artery atherosclerosis in women with coronary artery disease.
Matti Narkia

How Coconut Oil Could Help Reduce The Symptoms Of Type 2 Diabetes - 0 views

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    A new study in animals demonstrates that a diet rich in coconut oil protects against 'insulin resistance' (an impaired ability of cells to respond to insulin) in muscle and fat. The diet also avoids the accumulation of body fat caused by other high fat diets of similar calorie content. Together these findings are important because obesity and insulin resistance are major factors leading to the development of Type 2 diabetes. "
Matti Narkia

Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing ... - 0 views

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    Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression.
    Zhang H, Wei J, Xue R, Wu JD, Zhao W, Wang ZZ, Wang SK, Zhou ZX, Song DQ, Wang YM, Pan HN, Kong WJ, Jiang JD.
    Metabolism. 2009 Sep 3
    doi:10.1016/j.metabol.2009.07.029

    Liver function was improved greatly in these patients by showing reduction of liver enzymes. Our results confirmed the activity of BBR on InsR in humans and its relationship with the glucose-lowering effect. Together with our previous report, we strongly suggest BBR as an ideal medicine for T2DM with a mechanism different from metformin and rosiglitazone.
Matti Narkia

Efficacy of Berberine in Patients with Type 2 Diabetes - 0 views

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    Efficacy of berberine in patients with type 2 diabetes mellitus.
    Yin J, Xing H, Ye J.
    Metabolism. 2008 May;57(5):712-7.
    PMID: 18442638
    doi: 10.1016/j.metabol.2008.01.013.

    Fasting plasma insulin and homeostasis model assessment of insulin resistance index were reduced by 28.1% and 44.7% (P<.001), respectively. Total cholesterol and low-density lipoprotein cholesterol were decreased significantly as well. During the trial, 20 (34.5%) patients experienced transient gastrointestinal adverse effects. Functional liver or kidney damages were not observed for all patients. In conclusion, this pilot study indicates that berberine is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism

    In summary, that berberine is a potent oral hypoglycemic agent with modest effect on lipid metabolism. It is safe and the cost of treatment by berberine is very low. It may serve as a new drug candidate in the treatment of type 2 diabetes. However, this is a pilot study. The efficacy of berberine needs to be tested in a much larger population and characterized as a function of the known duration of the diabetes. Further studies are needed to evaluate the action of berberine on type 2 diabetes in other ethnic groups.
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