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Matti Narkia

Benefits of Vitamin D Supplementation - Journal of American Physicians and Surgeons Vol... - 1 views

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    Benefits of Vitamin D Supplementation
    Joel M. Kauffman, Ph.D.
    Journal of American Physicians and Surgeons
    Volume 14 Number 2 - Summer 2009

    Clinical trials show that vitamin D supplementation at higher
    levels than previously recommended is beneficial for many
    conditions. It decreases the frequency of falls and fractures, helps
    prevent cardiovascular disease, and reduces symptoms of colds or
    influenza. Benefits are also seen in diabetes mellitus, multiple
    sclerosis, Crohn disease, pain, depression, and possibly autism.
    Sunlight does not cause an overdose of vitamin D production,
    and toxicity from supplementation is rare. Dose recommendations
    are increasing, but appear to be lagging the favorable trial results. A
    number of common drugs deplete vitamin D levels, and others may
    limit its biosynthesis from sunlight.
    People with adequate levels from sun exposure will not benefit
    from supplementation. While dietary intake is helpful,
    supplementation is better able to raise serum 25-hydroxyvitamin D ,
    the major circulating metabolite, to the level now thought adequate,
    30-50 ng/mL.
    Where there is inadequate daily sun exposure, oral doses of
    1,000-2,000 IU/d are now considered routine, with much higher
    doses (up to 50,000 IU) for rapid repletion now considered safe.
Matti Narkia

More Good News About Vitamin D | Print Article | Newsweek.com - 0 views

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    "For more than 80 years, scientists have known that vitamin D is important for building bones. And for most of those 80 years, people thought this was the only thing it was good for. In the past decade, however, we've learned two important things about vitamin D: it appears to have many other important health effects, and many Americans don't get enough of it. In 2008, new research pointed to a vitamin D deficiency as a possible contributing factor in heart disease. And the suspected link between vitamin D deficiency and cancer grew even stronger. This surely will spur much new research in 2009.

    Why is vitamin D deficiency so common? The vitamin is made in our skin when sunlight strikes it. Many Americans-especially those who live in the northern part of the country, are elderly or have dark skin-don't soak up enough sun. And the vitamin isn't found in many foods. The main sources are fatty fish (such as salmon, mackerel, herring and sardines) and milk, cereal and juices that have been fortified with it. Vitamin D deficiency often is unsuspected because it causes no direct symptoms; like high blood pressure, it does its damage silently."
Matti Narkia

Vitamin D: a natural inhibitor of multiple sclerosis - 0 views

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    Vitamin D: a natural inhibitor of multiple sclerosis.
    Hayes CE.
    Proc Nutr Soc. 2000 Nov;59(4):531-5. Review.
    PMID: 11115787
Matti Narkia

Vitamin D metabolites as clinical markers in autoimmune and chronic disease. - Ann N Y ... - 0 views

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    Vitamin D metabolites as clinical markers in autoimmune and chronic disease.
    Blaney GP, Albert PJ, Proal AD.
    Ann N Y Acad Sci. 2009 Sep;1173:384-90.
    PMID: 19758177
    DOI: 10.1111/j.1749-6632.2009.04875.x
Matti Narkia

Overview of general physiologic features and functions of vitamin D -- DeLuca 80 (6): 1... - 0 views

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    Overview of general physiologic features and functions of vitamin D.
    DeLuca HF.
    Am J Clin Nutr. 2004 Dec;80(6 Suppl):1689S-96S. Review.
    PMID: 15585789
Matti Narkia

Reversing bacteria-induced vitamin D receptor dysfunction is key to autoimmune disease.... - 0 views

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    Reversing bacteria-induced vitamin D receptor dysfunction is key to autoimmune disease.
    Waterhouse JC, Perez TH, Albert PJ.
    Ann N Y Acad Sci. 2009 Sep;1173:757-65.
    PMID: 19758226
Matti Narkia

Animal Pharm: Hearts of Stone, Arteries of Glass - 0 views

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    A recent Wall Street Journal article "Defending Against Disease -- With Vitamin D New Studies Suggest It Isn't Just Bones That Might Benefit" by the wonderful Melinda Beck highlights benefits of Vitamin D3. In TYP, we've known the benefits for years :) but it's nice to see the rest of the world catching up.

    The benefits of Vitamin D3 are potent, powerful immunomodulation -- to the point where autoimmune diseases, viral and bacterial infections and cancer are effectively reduced. What is the value for heart disease and diabetes prevention? In hemodialysis patients, great lessons are can be learned. Nephrologists often describe patients with severe (stage 5) chronic kidney disease (CKD) patients on hemodialysis as having 'hearts of stone, blood vessels of glass.' Unfortunately over 70% of chronic hemodialysis patients have coronary artery disease (and Lp(a)). What medical science shows is that Agatston coronary calcification scores can be dramatically reduced when vitamin D is replenished and calcium is restricted. Sevelamer (Renagel) is a calcium-free, metal-free polymer phosphate binder. In 52-weeks, calcium restriction, a phosphate-binder and vitamin D resulted in one individual in a 21% reduction in Agatston CAC score (from 968 to 756; see Figure 2).
Matti Narkia

The health benefits of vitamin D greatly outweigh the health risks - 0 views

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    In his recent essay, Trevor G. Marshall explores how vitamin D supplementation may be contributing to the current epidemics of obesity and chronic disease[1]. Unfortunately, he has overlooked many important papers that disagree with his hypothesis. This letter points out some of the omissions.
    The health benefits of vitamin D3 have been reviewed recently[2]. The benefits for bone health have been known for nearly a century. Benefits for cancer, infectious diseases, autoimmune diseases, and metabolic diseases have been identified in the past three decades.
Matti Narkia

Vitamin D: the alternative hypothesis. - Autoimmun Rev. 2009 Jul;8(8):639-44. (full tex... - 0 views

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    Vitamin D: the alternative hypothesis.
    Albert PJ, Proal AD, Marshall TG.
    Autoimmun Rev. 2009 Jul;8(8):639-44. Epub 2009 Feb 12. Review.
    PMID: 19393200

    Emerging molecular evidence suggests that symptomatic improvements among those administered vitamin D is the result of 25-D's ability to temper bacterial-induced inflammation by slowing VDR activity. While this results in short-term palliation, persistent pathogens that may influence disease progression, proliferate over the long-term.
Matti Narkia

Immunosteroid as a regulator for Th1/Th2 balance: its possible role in autoimmune disea... - 0 views

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    Immunosteroid as a regulator for Th1/Th2 balance: its possible role in autoimmune diseases.
    Matsuzaki J, Tsuji T, Imazeki I, Ikeda H, Nishimura T.
    Autoimmunity. 2005 Aug;38(5):369-75. Review.
    PMID: 16227152
Matti Narkia

Vitamin D: The alternative hypothesis. - ScienceDirect - Autoimmunity Reviews, 2009 - 0 views

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    Albert et al. Vitamin D: The alternative hypothesis.
    Autoimmunity Reviews, 2009
    doi:10.1016/j.autrev.2009.02.011 
Matti Narkia

Low Levels Of Vitamin D In Patients With Autoimmune Disease May Be Result, Not Cause, O... - 0 views

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    ScienceDaily (Apr. 8, 2009) - Deficiency in vitamin D has been widely regarded as contributing to autoimmune disease, but a review appearing in Autoimmunity Reviews explains that low levels of vitamin D in patients with autoimmune disease may be a result rather than a cause of disease and that supplementing with vitamin D may actually exacerbate autoimmune disease.
Matti Narkia

Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, ... - 0 views

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    Holick MF.
    Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease.
    Am J Clin Nutr. 2004 Dec;80(6 Suppl):1678S-88S. Review.
    PMID: 15585788 [PubMed - indexed for MEDLINE]
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