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Matti Narkia

25-Hydroxyvitamin D3 is an agonistic vitamin D receptor ligand - Lou et al. - J Steroi... - 1 views

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    25-Hydroxyvitamin D(3) is an agonistic vitamin D receptor ligand.
    Lou YR, Molnár F, Peräkylä M, Qiao S, Kalueff AV, St-Arnaud R, Carlberg C, Tuohimaa P.
    J Steroid Biochem Mol Biol. 2009 Nov 26. [Epub ahead of print]
    PMID: 19944755
    doi:10.1016/j.jsbmb.2009.11.011

    In conclusion, 25-hydroxyvitamin D3 is an agonistic vitamin D receptor ligand with gene regulatory and anti-proliferative properties.
Matti Narkia

New topics in vitamin D research - Google Books - 2 views

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    Table of Contents

    Ch. I Is calcidiol an active hormone? 1
    Ch. II Vitamin D as a neurosteroid hormone : from neurobiological effects to behavior 29
    Ch. III Inhibitors of vitamin D hydroxylases : mechanistic tools and therapeutic aspects 67
    Ch. IV Vitamin D analogues as anti-cancer therapies 145
    Ch. V Paricalcitol : a vitamin D2 analog with anticancer effects with low calcemic activity 169
    Ch. VI Vitamin D use among older adults in U.S. : results form national surveys 1997 to 2002 181
    Ch VII Vitamin D deficiency in migrants 199

    Vitamin D is a fat-soluble steroid hormone precursor that contributes to the maintenance of normal levels of calcium and phosphorus in the bloodstream. Strictly speaking, it is not a vitamin since human skin can manufacture it, but it is referred to as one for historical reasons. It is often known as calciferol. The major biologic function of vitamin D is to maintain normal blood levels of calcium and phosphorus. Vitamin D aids in the absorption of calcium, helping to form and maintain strong bones. It promotes bone mineralisation in concert with a number of other vitamins, minerals and hormones. Without vitamin D, bones can become thin, brittle, soft or misshapen. Vitamin D prevents rickets in children and osteomalacia in adults -- skeletal diseases that result in defects that weaken bones. This book gathers international research on the leading-edge of the scientific front.
Matti Narkia

25-Hydroxyvitamin D3 is an agonistic vitamin D receptor ligand - ScienceDirect - The Jo... - 0 views

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    25-Hydroxyvitamin D(3) is an agonistic vitamin D receptor ligand.
    Lou YR, Molnár F, Peräkylä M, Qiao S, Kalueff AV, St-Arnaud R, Carlberg C, Tuohimaa P.
    J Steroid Biochem Mol Biol. 2009 Nov 26. [Epub ahead of print]
    PMID: 19944755
    doi:10.1016/j.jsbmb.2009.11.011

    In conclusion, 25-hydroxyvitamin D3 is an agonistic vitamin D receptor ligand with gene regulatory and anti-proliferative properties.
Matti Narkia

Long-term vitamin D3 supplementation may have adverse effects on serum lipids during po... - 0 views

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    Long-term vitamin D3 supplementation may have adverse effects on serum lipids during postmenopausal hormone replacement therapy.
    Heikkinen AM, Tuppurainen MT, Niskanen L, Komulainen M, Penttilä I, Saarikoski S.
    Eur J Endocrinol. 1997 Nov;137(5):495-502.
    PMID: 9405029

    CONCLUSIONS: Our results confirm the positive long-term effect of HRT with sequential estradiol valerate and cyproterone acetate on serum lipid concentrations. In addition, the results suggest that vitamin D3 supplementation may have unfavorable effects on lipids in postmenopausal women. Pure vitamin D3 treatment was associated with increased serum LDL cholesterol. Furthermore, the beneficial effects of HRT on serum LDL cholesterol content were reduced when estradiol valerate was combined with vitamin D3. However, the relevance of these associations to cardiovascular morbidity remains to be established.
Matti Narkia

Calcidiol and prostate cancer - ScienceDirect - The Journal of Steroid Biochemistry and... - 0 views

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    Calcidiol and prostate cancer.
    Tuohimaa P, Golovko O, Kalueff A, Nazarova N, Qiao S, Syvälä H, Talonpoika R, Lou YR.
    J Steroid Biochem Mol Biol. 2005 Feb;93(2-5):183-90. Epub 2005 Jan 22. Review.
    PMID: 15860261
Matti Narkia

25-Hydroxyvitamin D3 is an active hormone in human primary prostatic stromal cells -- L... - 0 views

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    25-hydroxyvitamin D3 is an active hormone in human primary prostatic stromal cells.
    Lou YR, Laaksi I, Syvälä H, Bläuer M, Tammela TL, Ylikomi T, Tuohimaa P.
    FASEB J. 2004 Feb;18(2):332-4. Epub 2003 Dec 4.
    PMID: 14657005
Matti Narkia

Why "Vitamin D" is not a hormone, and not a synonym for 1,25-dihydroxy-vitamin D, its a... - 0 views

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    Why "Vitamin D" is not a hormone, and not a synonym for 1,25-dihydroxy-vitamin D, its analogs or deltanoids.
    Vieth R.
    J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):571-3.
    PMID: 15225841
    doi:10.1016/j.jsbmb.2004.03.037
Matti Narkia

Immunosteroid as a regulator for Th1/Th2 balance: its possible role in autoimmune disea... - 0 views

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    Immunosteroid as a regulator for Th1/Th2 balance: its possible role in autoimmune diseases.
    Matsuzaki J, Tsuji T, Imazeki I, Ikeda H, Nishimura T.
    Autoimmunity. 2005 Aug;38(5):369-75. Review.
    PMID: 16227152
Matti Narkia

Vitamin D and disease prevention with special reference to cardiovascular disease - Ent... - 0 views

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    Zittermann A.
    Vitamin D and disease prevention with special reference to cardiovascular disease.
    Prog Biophys Mol Biol. 2006 Sep;92(1):39-48. Epub 2006 Feb 28. Review.
    PMID: 16600341 [PubMed - indexed for MEDLINE]
Matti Narkia

Vitamin D physiology - Entrez PubMed - 0 views

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    Lips P.
    Vitamin D physiology.
    Prog Biophys Mol Biol. 2006 Sep;92(1):4-8. Epub 2006 Feb 28. Review.
    PMID: 16563471 [PubMed - indexed for MEDLINE]
Matti Narkia

Putting cardiovascular disease and vitamin D insufficiency into perspective. - 0 views

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    Zittermann A, Schleithoff SS, Koerfer R. Putting cardiovascular disease and vitamin D insufficiency into perspective.Br J Nutr. 2005 Oct;94(4):483-92. Review.PMID: 16197570 [PubMed - indexed for MEDLINE]
Matti Narkia

Vitamin D status and parathyroid hormone in obese children before and after weight loss... - 0 views

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    Reinehr T, de Sousa G, Alexy U, Kersting M, Andler W.
    Vitamin D status and parathyroid hormone in obese children before and after weight loss.
    Eur J Endocrinol. 2007 Aug;157(2):225-32.
    PMID: 17656603 [PubMed - in process]
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