We're Not "DON" Yet: Optimal Dosing and Prodrug Delivery of 6-Diazo-5-oxo-L-norleucine ... - 0 views
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Glutamine is the most abundant amino acid in blood
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Rapidly proliferating healthy cells (GI epithelium, lymphocytes) or cells under physiologic stress have increased demand for glutamine
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Glutamine is transported into cells by one of multiple amino acid transporters (e.g. ASCT2, BOAT2), several of which are thought to be upregulated in cancer cells
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DON of Hope: Starving Pancreatic Cancer by Glutamine Antagonism | Cancer Research | Ame... - 0 views
Cellular senescence: a double-edged sword in cancer therapy - PMC - 0 views
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cellular senescence has been identified in cancer patients undergoing chemotherapy and radiotherapy
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