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Diet and Herbal Remedies for Ulcerative Colitis - 0 views

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    It is an inflammatory, refractory disease which includes colon, rectum and little part of small intestine. The person who is suffering from Ulcerative colitis in tests shows ulcers inside the colon. Ulcerative colitis comes under the category of ...
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    It is an inflammatory, refractory disease which includes colon, rectum and little part of small intestine. The person who is suffering from Ulcerative colitis in tests shows ulcers inside the colon. Ulcerative colitis comes under the category of ...
Nathan Goodyear

Evaluation of dairy allergy among ulcerative colitis patients - 0 views

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    dairry sensitivity associated with ulcerative colitis; intake associated with flare in colitis.
Nathan Goodyear

Combined oral sodium butyrate and mesalazine treatment compared to oral mesalazine alone in ulcerative colitis: randomized, double-blind, placebo-c... - PubMed - NCBI - 0 views

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    4 grams of daily butyrate found to be a goo adjunct in therapy for ulcerative colitis.
Nathan Goodyear

Randomized, double-blind, placebo-controlled trial of oral aloe vera gel for active ulcerative colitis - Langmead - 2004 - Alimentary Pharmacology & Therapeutics - Wiley Online Library - 0 views

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    aloe vera at 200 ml in a twice daily dosing found to improve significantly Ulcerative colitis.
Nathan Goodyear

Natural products in treatment of ulcerative colitis and peptic ulcer - 0 views

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    review of science behind natural therapies in ulcerative colitis
Nathan Goodyear

Endogenous Levels of Circulating Androgens and Risk of Crohn's Disease and Ulcerative Colitis Among Women: A Nested Case-Control Study from the Nur... - PubMed - NCBI - 0 views

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    serum Testosterone levels increasing in the normal range were found to be associated with a reduced risk of Crohn's disease in women.   No such relationship was found with ulcerative colitis, with DHEA, or with SHBG.
Nathan Goodyear

Calprotectin is a stronger predictive marker of relapse in ulcerative colitis than in Crohn's disease -- Costa et al. 54 (3): 364 -- Gut - 0 views

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    Fecal Calprotectin found to be useful as monitor for Ulcerative colitis relapse.  This was found more specific for UC than Crohn's disease.  There was a 14 fold higher relapse risk in those with levels > 150.
Nathan Goodyear

Vinegar Treatment Prevents the Development of Murine Experimental Colitis via Inhibition of Inflammation and Apoptosis - Journal of Agricultural and Food Chemistry (ACS Publications) - 0 views

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    vinegar shown to reduce inflammation through Th1 and Th17 suppression in mice model of ulcerative colitis.
Nathan Goodyear

VSL#3 probiotic-mixture induces remission... [Am J Gastroenterol. 2005] - PubMed - NCBI - 0 views

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    high dose probiotic shown to provide significant benefit, even remission in those with mild/moderate ulcerative colitis.
Nathan Goodyear

Low S-adenosylmethionine concentrations fo... [Clin Chem Lab Med. 2004] - PubMed - NCBI - 0 views

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    SAMe found to be low in those with Crohn's and Ulcerative colitis disease.  Is IBD a methylation disease?  Is IBD a detoxification deficiency state due to lack of methylation?
Nathan Goodyear

saccharomyces cerevisiae and ulcerative colitis - Google Scholar - 0 views

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    Saccharomyces cerevisiae and IBD.
Nathan Goodyear

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1027123/pdf/gut00037-0069.pdf - 0 views

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    SCFA and ulcerative colitis
Nathan Goodyear

Curcumin Maintenance Therapy for Ulcerative Colitis: Randomized, Multicenter, Double-Blind, Placebo-Controlled Trial - 0 views

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    Curcumin reduces inflammation and improves maintenance in Ulcerative Collitis
Nathan Goodyear

Thieme E-Journals - Planta Medica / Abstract - 0 views

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    900 mg Boswellia found to aid treatment of chronic colitis
Nathan Goodyear

Efficacy of quercetin derivatives in prevention of ulcerative colitis in rats : Interdisciplinary Toxicology - 0 views

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    animal study finds natural quercetin, a flavonoid reduces inflammation in rats with UC.
Nathan Goodyear

Herbal Medicine in the Treatment of Ulcerative Colitis - 0 views

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    nice literature review of natural therapies for the treatment of UC.
Nathan Goodyear

Advances in treatment of ulcerative colitis with herbs: From bench to bedside - 0 views

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    additional reviews of natural therapies and IBD.
Nathan Goodyear

Acetyl-11-keto-beta-boswellic acid, a constituent of a herbal medicine from Boswellia serrata resin, attenuates experimental ileitis. - PubMed - NCBI - 0 views

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    animal study finds Boswellia reduces inflammation in Inflammatory Bowel Disease.
Nathan Goodyear

Limited effects of dietary curcumin on Th-1 driven colitis in IL-10 deficient mice suggest an IL-10-dependent mechanism of protection - 0 views

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    curcumin shown to inhibit NF-kappaB through a IL-10 dependent pathway.  IL-10 is required and curcumin appears to augment the inhibition of NF-kappaB
Nathan Goodyear

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism - 0 views

  • Acetate, propionate, and butyrate are present in an approximate molar ratio of 60:20:20 in the colon and stool
  • SCFAs might play a key role in the prevention and treatment of the metabolic syndrome, bowel disorders, and certain types of cancer
  • SCFA administration positively influenced the treatment of ulcerative colitis, Crohn's disease, and antibiotic-associated diarrhea
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  • Gut bacteria in the cecum and large intestine produce SCFAs mainly from nondigestible carbohydrates that pass the small intestine unaffected
  • plant cell-wall polysaccharides, oligosaccharides, and resistant starches
  • inulin shifted the relative production of SCFAs from acetate to propionate and butyrate
  • age of approximately 3–4 years, when it becomes mature
  • SCFAs affect lipid, glucose, and cholesterol metabolism
  • colonocytes, the first host cells that take up SCFAs and which depend largely on butyrate for their energy supply
  • the microbiota educate the immune system and increase the tolerance to microbial immunodeterminants
  • the microbiota act as a metabolic organ that can break down otherwise indigestible food components, degrade potentially toxic food compounds like oxalate, and synthesize certain vitamins and amino acids
  • a large part of the SCFAs is used as a source of energy
  • The general idea is that colonocytes prefer butyrate to acetate and propionate, and oxidize it to ketone bodies and CO2
  • Exogenous acetate formed by colonic bacterial fermentation enters the blood compartment and is mixed with endogenous acetate released by tissues and organs (103, 104). Up to 70% of the acetate is taken up by the liver (105), where it is not only used as an energy source, but is also used as a substrate for the synthesis of cholesterol and long-chain fatty acids and as a cosubstrate for glutamine and glutamate synthesis
  • SCFAs regulate the balance between fatty acid synthesis, fatty acid oxidation, and lipolysis in the body.
  • Fatty acid oxidation is activated by SCFAs, while de novo synthesis and lipolysis are inhibited
  • obese animals in this study showed a 50% reduction in relative abundance of the Bacteroidetes (i.e., acetate and propionate producers), whereas the Firmicutes (i.e., butyrate producers) were proportionally increased compared with the lean counterparts.
  • increase in total fecal SCFA concentrations in obese humans.
  • In humans the distinct relation between the Firmicutes:Bacteroidetes ratio and obesity is less clear.
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    Great review of the role of SCFA in gut health and body metabolism
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