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Nathan Goodyear

Clinical significance of colonic fermenta... [Am J Gastroenterol. 1990] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...2220719

n-butyrate inflammation inflammatory bowel disease IBD ulcerative colitis Chron's cancer

shared by Nathan Goodyear on 09 Sep 11 - No Cached
  • Nathan Goodyear on 09 Sep 11
     
    low n-butyrate implicated in inflammatory bowel conditions
Nathan Goodyear

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1027123/pdf/gut00037-0069.pdf - 0 views

www.ncbi.nlm.nih.gov/...gut00037-0069.pdf

SCFA ulcerative colitis UC n-butyrate butyrate butyrate enema

shared by Nathan Goodyear on 06 Mar 17 - No Cached
  • Nathan Goodyear on 06 Mar 17
     
    SCFA and ulcerative colitis
Nathan Goodyear

Metabolic Effects of Dietary Fiber Consumption and Prevention of Diabetes - 0 views

jn.nutrition.org/...439.long

soluble insoluble fiber dietary diet nutrition diabetes

shared by Nathan Goodyear on 22 Oct 13 - No Cached
  • DF are highly complex substances that can be described as any nondigestible carbohydrates and lignins not degraded in the upper gut
  • Commonly, DF are classified according to their solubility in water, even though grading according to viscosity, gel-forming capabilities, or fermentation rate by the gut microbiota might be physiologically more relevant
  • Main sources of soluble DF are fruits and vegetables
  • ...8 more annotations...
  • n increased intake of total DF was inversely associated with markers of insulin resistance in several studies
  • consumption of insoluble DF increased whole body glucose disposal independent of changes in body weight in both short-term and more prolonged studies
  • Short-chain fatty acids (SCFA) such as acetate, propionate, and butyrate are produced by bacterial fermentation of indigestible DF polysaccharides in the colon
  • increased production of SCFA is assumed to be beneficial by reducing hepatic glucose output and improving lipid homeostasis
  • a high DF diet (oligofructose) reduced gram-negative bacterial content and body weight, whereas a high fat diet increased the proportion of a gram-negative bacterial lipopolysaccharides (LPS) containing microbiota in humans
  • Prospective cohort studies indicate that diets high in insoluble cereal DF and whole grains might reduce diabetes risk
  • soluble DF (i.e., pectin, inulin, and β-glucans)
  • cereal DF (i.e., cellulose and hemicelluloses)
  • Nathan Goodyear on 22 Oct 13
     
    Good discussion of dietary fiber intake and Diabetes.  
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