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Nathan Goodyear

The Contribution of Cytotoxic Chemotherapy to 5-year Survival in Adult Malignancies | C... - 0 views

  • In this group, the 5-year survivalrateduesolelytocytotoxicchemotherapywas14%
  • There is also no convincing evidence that usingregimens with newer and more expensive drugs are anymore beneficial than the regimens used in the 1970s
  • two systematic reviews of chemotherapy inrecurrent or metastatic breast cancer have not been able toshow any survival benefit
  • ...12 more annotations...
  • The five most common adult malignancies (colorectal, breast, prostate, melanoma and lung cancer)
  • n breast cancer, the optimal regimen(s) for cytotoxicchemotherapy in recurrent/metastatic disease are still notdefined, despite over 30 years of ‘research’ and a plethora of RCTs since the original Cooper regimen was published in1969
  • The five most ‘chemo-sensitive’ cancers,namely testis, Hodgkin’s disease and non-Hodgkin’s lym- phoma, cervix and ovary
  • only 13 out of the 22 malignancies evaluated showed any improvement in 5-year survival, and theimprovement was greater than 10% in only three of those13 malignancies
  • the contribution of curative and adjuvant cytotoxic chemotherapy to 5-year survival in adults is 2.3% in Australia and 2.1% in the USA
  • a benefit of less than 2.5% is likely to be applicable in other developed countries
  •   Overview The Contribution o
  • the benefit of cytotoxic chemotherapy may have been overestimated for cancers of oesophagus, stomach,rectum and brain.
  • this reflects the presentation of results as a ‘reduction in risk’ rather than asan absolute survival benefit[89,90]and by exaggerating theresponse rates by including ‘stable disease’
  • recent studies have documented impaired cognitive function inwomen receiving adjuvant treatment for breast cancer
  • the 5-year survival rate due solely to cytotoxicchemotherapy was 1.6%
  • the value of palliative chemotherapy has beenquestioned
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    Incredibly low impact of cytotoxic chemotherapy despite its wide spread utilization.  This article referenced cost yet did not evaluate the cost of cytotoxic side effect.  The question to answer: is Cytotoxic chemotherapy a valid treatment, at all, for the majority of cancers.
spineneuro

Robotic Spine Surgery Program By Dr. Vidyadhara S Spine Surgeon in Bangalore - 0 views

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    Dr. Vidyadhara S spine surgeon in Bangalore specializes in complex reconstructions and revision surgery, along with treatment of spinal deformity, tumors, and minimally invasive techniques to the spinal column.
spineneuro

The Very Best in Spine Care in India Begins With Dr. Vidyadhara S - 0 views

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    Dr. Vidyadhara S offers a multi-disciplinary approach to care that permits him to provide you, the patient, with best practice. Top spine specialist at Manipal Hospital Bangalore performs more outpatient, minimally invasive spine surgeries each month than any other spine surgeon in the world.
spineneuro

Opt For Spine Surgery in India By Dr. Vidyadhara S in Manipal Hospital - 0 views

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    Top spine specialist in Bangalore, he conducts more outpatient, minimally invasive spine procedures each month than any other spine practitioner worldwide. Dr. Vidyadhara S Manipal Hospital is equipped to provide advice, recommendations, and spine surgical procedures to assist you in reclaiming a full and comfortable life.
Nathan Goodyear

Glutathione S-transferase activity in epithelial ovarian cancer: Association with respo... - 0 views

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    higher glutathione S-transferase activity associated with improved survival and response with chemotherapy.
fitspresso

https://www.fitspresso-co.com/ - 0 views

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    FitSpresso™ | Official Site fitspresso-co.com FitSpresso Only $39/Bottle Limited Time Offer! FitSpresso Special Deal + Special 51% Discount Save $660 + 180 Days Money Back Guarantee FitSpresso Herpesyl Five Star A dietary product formulated to assist users in reducing weight can increase other advantages that can support overall health. This product can assist users in getting closer to the desirable body weight. Regular Price: 149/per bottle Only for: $39/per bottle Buy Now What IsFitSpresso? FitSpresso is promoted as a natural supplement that comes in the form of diet pills, and it can aid in rapid and efficient weight loss, similar to many other supplements. The term "natural supplements refers to a nutritional supplement that is made entirely of natural, chemical-free materials. You can utilize these organic ingredients to aid in natural weight loss. It can speed up your body's metabolism and assist with other crucial processes. All parts of our bodies are impacted by weight increase, and not only do we need to deal with the increased weight, but we also need to deal with the numerous problems and illnesses that come along with it. This refers to the risk of developing chronic cardiac conditions, low blood pressure, and, in some circumstances, problems with blood sugar. However, FitSpresso even with its bright and bold claims, can help you efficiently manage your weight and completely avoid these extra uncomfortable problems. FitSpresso is a supplement that comes in the form of a pill, which makes it tasty, simple to swallow, and handy. According to the manufacturer, these diet tablets are GMO-free and toxic-free, making them edible. This is why we have things such as weight loss supplements. Thanks to modern advancements, we can just take a dietary supplement pill to bring about significant weight loss in a completely healthy and natural manner. Not only this, but dietary supplements can also support healthy blood sugar levels and help with
spineneuro

Courageous Steps: Arwa Thani's Battle with Spinal Cord Tumors in India - 0 views

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    Through her resilience and the expertise of Dr. Vidyadhara S at Max Hospital Bangalore, she not only conquered spinal cord tumors but also inspired a ripple of hope that reverberated across borders. As we traverse the labyrinth of life, may Arwa's story remind us that amidst the darkness, there's always a flicker of hope-a guiding light leading us toward healing and renewal.
Nathan Goodyear

Neurobiological and Neuropsychiatric Effects of Dehydroepiandrosterone (DHEA) and DHEA ... - 0 views

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    Everything you wanted to know about DHEA, DHEA-S in general and as they relate to neuropsychiatry.
Phiten Singapore

Walk & Run in Style with Phiten' s Rakuwa Anklets - 0 views

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    Mix style and comfort when you wear the newest addition to #Phiten's accessories. Get the relief your legs, feet, and ankles need with the #Rakuwa #Anklet S Slash Line. Find the #PhitenStore nearest to you: https://phitensg.com/store-locations/
Jadibuti jadibuti.net

Top 5 Herbs to Manage Depression and Anxiety Naturally - 0 views

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    Depression is one of the major havocs to human health today that has engulfed a major part of the population. What’s more alarming is the fact that it is prevailing in a lot of young and middle aged people. Depression is a condition ...
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    Depression is one of the major havocs to human health today that has engulfed a major part of the population. What’s more alarming is the fact that it is prevailing in a lot of young and middle aged people. Depression is a condition ...
Jadibuti jadibuti.net

Swine Flu Precautions at Home - 0 views

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    Swine flu is disease caused by H1N1 Virus. Swine flu spread almost all states in India and report from India's Health ministry suggest death of over 1000 people and approximately 20000 cases reported this year. Swine flu is contagious and s ...
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    Swine flu is disease caused by H1N1 Virus. Swine flu spread almost all states in India and report from India's Health ministry suggest death of over 1000 people and approximately 20000 cases reported this year. Swine flu is contagious and s ...
Nathan Goodyear

Effect of DHEA-sulfate on adiponectin gene expression in adipose tissue from different ... - 0 views

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    DHEA-S shown to increase genetic expression of adiponectin in human adipose tissue.  This has enormous implications on the link between DHEA and insulin resistance induce obesity. This is a peripheral tissue problem, not a central problem.
Nathan Goodyear

Dehydroepiandrosterone (DHEA)-A Precursor Steroid or an Active Hormone in Human Physiol... - 0 views

  • no significant adverse or negative side effects of DHEA were reported in clinical studies of men and women.
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    review of the clinical studies of DHEA and DHEA-S find no negative side-effects: only positive effects.  Overdosage of DHEA, which is common in women, obviously can result in side effects, though.
Nathan Goodyear

Meta-analysis: effect of hormone-replacement therapy on components of the metabolic syn... - 0 views

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    HRT improves MetS.  Oral estrogen increased CRP and protein S, but not transdermal.
Abdullah Kul

Phen375 Phentemine Fat Burner - 0 views

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    Phen375 is a pharmacy grade food supplement with diet program included - both extensive diet plans and exercise video instructions. It is great choice for people who look for that extra to help them with losing weight and getting motivation. Phen375 is food supplement and would greatly compliment your existing weight loss and dieting promotions (especially those attracting American search traffic). Why to promote Phen375 - Most paying weight loss sector merchant - One of highest EPC amongst diet products - Most profitable merchant for the affiliates in 2011, 2012 and 2013 - Reorder ratios ranging between 21- 33% - Top range conversion rates Phen375 offers highly converting website, ensuring you get highest return possible on your traffic. Also you will find wealth of resources, such as articles, product images and banners to help with your promotions. Also if you have any questions or need help with promotions, please contact Phen375's dedicated affiliate manager - Catherine Day. You can see her details on the right.
Nathan Goodyear

Dehydroepiandrosterone and its sulfate predict the 5-year risk of coronary heart diseas... - 0 views

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    low DHEA and DHEA-S associated with increased risk of Coronary Heart Disease in elderly men.
Nathan Goodyear

http://www.biomedcentral.com/content/pdf/1756-0500-3-204.pdf - 0 views

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    salivary DHEA-S ranges from 4-10 ng/dl in men versus 1-5 in women with no variance between drool or cotton technique.
Nathan Goodyear

Mucosal Immunology - Molecular signatures of a disturbed nasal barrier function in the ... - 0 views

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    nasal mucos colonization of S aureus found to be associated with Wegener's vasculitis as well as relapse.
Nathan Goodyear

S-adenosyl-l-methionine (SAMe) as antidepressant: ... [Acta Neurol Scand Suppl. 1994] -... - 0 views

  • The efficacy of SAMe in treating depressive syndromes and disorders is superior with that of placebo and comparable to that of standard tricyclic antidepressants. Since SAMe is a naturally occurring compound with relatively few side-effects, it is a potentially important treatment for depression
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    S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies.
Nathan Goodyear

The association between serum dehydroepiandrosterone sulfate (DHEA-... - PubMed - NCBI - 0 views

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    Only abstract available here, but lower DHEA-S (still in reference normal range) associated with lower bone mineral density and increased osteoporosis risk.
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