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Causes And Symptoms Of PCOS | Your Health Our Priority - 0 views

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    PCOS is a disease of the female reproductive system that is characterized by hairiness, infrequent or heavy periods, skin disorders and infertility. Its symptoms and causes need immediate medical care as it can be deadly.
Nathan Goodyear

The Contribution of Cytotoxic Chemotherapy to 5-year Survival in Adult Malignancies | C... - 0 views

  • In this group, the 5-year survivalrateduesolelytocytotoxicchemotherapywas14%
  • There is also no convincing evidence that usingregimens with newer and more expensive drugs are anymore beneficial than the regimens used in the 1970s
  • two systematic reviews of chemotherapy inrecurrent or metastatic breast cancer have not been able toshow any survival benefit
  • ...12 more annotations...
  • The five most common adult malignancies (colorectal, breast, prostate, melanoma and lung cancer)
  • n breast cancer, the optimal regimen(s) for cytotoxicchemotherapy in recurrent/metastatic disease are still notdefined, despite over 30 years of ‘research’ and a plethora of RCTs since the original Cooper regimen was published in1969
  • The five most ‘chemo-sensitive’ cancers,namely testis, Hodgkin’s disease and non-Hodgkin’s lym- phoma, cervix and ovary
  • only 13 out of the 22 malignancies evaluated showed any improvement in 5-year survival, and theimprovement was greater than 10% in only three of those13 malignancies
  • the contribution of curative and adjuvant cytotoxic chemotherapy to 5-year survival in adults is 2.3% in Australia and 2.1% in the USA
  • a benefit of less than 2.5% is likely to be applicable in other developed countries
  •   Overview The Contribution o
  • the benefit of cytotoxic chemotherapy may have been overestimated for cancers of oesophagus, stomach,rectum and brain.
  • this reflects the presentation of results as a ‘reduction in risk’ rather than asan absolute survival benefit[89,90]and by exaggerating theresponse rates by including ‘stable disease’
  • recent studies have documented impaired cognitive function inwomen receiving adjuvant treatment for breast cancer
  • the 5-year survival rate due solely to cytotoxicchemotherapy was 1.6%
  • the value of palliative chemotherapy has beenquestioned
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    Incredibly low impact of cytotoxic chemotherapy despite its wide spread utilization.  This article referenced cost yet did not evaluate the cost of cytotoxic side effect.  The question to answer: is Cytotoxic chemotherapy a valid treatment, at all, for the majority of cancers.
Nathan Goodyear

Neuroendocrine androgen action is a key extraovarian mediator in the development of pol... - 0 views

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    Androgen receptors in the brain may be key in metabolic effects found in PCOS
Nathan Goodyear

Dietary composition in the treatment of polycystic ovary syndrome: a systematic review ... - 0 views

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    Weight loss is the best positive effect for women with PCOS.  Higher fat and protein, with a lower carb diet benefited women with PCOS.  A low Glycemic index plan benefited women with PCOS.  
Nathan Goodyear

Lifestyle changes in women with polycystic ovary syndrome. - PubMed - NCBI - 0 views

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    Cochran review of 6 studies of only 164 women found lifestyle interventions improved body composition, mostly fat loss, decreased the hyperandrogen status and improved insulin resistance in women with PCOS.
Nathan Goodyear

Increased serum C-reactive protein levels in normal weight women with polycystic ovary ... - 0 views

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    Study doesn't directly link causation, but increased Testosterone in women of normal weight with PCOS associated with increased CRP.
Nathan Goodyear

Thyroid disorders and polycystic ovary syndrome: An emerging relationship - 0 views

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    good read on the association and common finding of hypothyroid and PCOS--no causation link.
Nathan Goodyear

Thieme E-Journals - Hormone and Metabolic Research / Abstract - 0 views

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    Short study found that Selenium improved pregnancy rate compared to placebo, reduced DHEA, hirsutism, CRP and MDA
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