Article discusses the immunoexcitotoxic process involved in chronic TBI. This is likely to be the underlying process involved in NFL and other football players delayed neurological effects. A similar process has been see in combat veterans returning from the theatre.
This article discusses the many potential causes of the increasing autism epidemic. One listed is the toxic pregnant/infant environment and the immunoexcitotoxic impact.
methylmercury mediates neurotoxicity via mitochondrial damage, inflammation, and oxidative stress. Astrocytes accumulated the methyl mercury. The destruction of the astrocytes will result in an increase in glutamate. Methylmercury is synergistic with other toxins in the development of immunoexcitotoxicity.