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this study revealed symptom improvement with hydrocortisone treatment in those with CFS. Pre/post treatment was with serum cortisol and not salivary cortisol.  This is a weakness of the study.  The starting dosage of 25-30 mg hydrocortisone is high and with inadequate evaluation, this high dosage could have resulted in high dosage and adrenal suppression.  

Older study, 1995, but shows the long-standing evidence that IVC preferentially is cytotoxic to cancer cells.`

older study.  High dosage vitamin B6 associated with short term ataxia and and neuropathy.  This resolved following removal.   Dosage unknown.

small dosage of vitamin D3 statistically reduces risk of cold and flu during winter season.  Small dosage of 2,000 IU used.

This study found a pro oxidant effect of the addition of 5 grams of IV vitamin C with EDTA chelation.  As dosing of IV vitamin C goes, 5 grams is quite small.  Vitamin C has been shown to have varying effects (pro oxidant versus antioxidant) dictated by the dosage.  One wonders if higher dosing IV vitamin C provides antioxidant effects?

Age seems to predict metabolism of testosterone in those receiving testosterone therapy.  Older men appear to have slower metabolism of testosterone.  This implies that one can likely dose "older" men at lower dosages.

animal study finds vitamin C improves hypertension via renovascular source and oxidative stress.  The dosage was 150 mg/kg/day.  This would be equivalent to 10,800 grams daily for a 72 human.  But what about a 200 lb male or female?  That would be 13,650 grams of vitamin C daily.

low dosage HCG maintains ITT.

study looks at cycling Testosterone as athletes do.  The point to take from this study is that they lowered the standard Testosterone dosage by 50% and got the same results.  Traditional medicine drastically overdoses men with Testosterone.

Testosterone shown to improve GLUT 4 and IRS-1 expression with low dose short term therapy; in contrast, high dose, prolonged therapy shown to down regulate IRS-1 and GLUT 4 expression.  This shows the importance of using saliva for evaluation versus serum.  Serum testing routinely leads to over treatment with high dosages of testosterone.

I look forward to the published results of this study as this abstract references the WHI as the "same entry" criteria.  I imagine the HRT would be the same too, but will wait to see.  There is a serious problem with proper reporting of synthetic estrogens as bioidentical estrogens and synthetic progestins as bioidentical progesterone;  Also, what is the dosage. Most individuals are massively overdosed.  This study was said to be a "landmark".  Could just be don't use synthetic hormones: which is what the WHI said.

this study revealed increased breast cancer risk in women on "estrogen" and "testosterone" therapy.  Now, several problems here: first, are these synthetic hormone or bioidentical.  Second, the dosages appear, in what is written, to be supra physiologic.  Third, giving supra physiologic estradiol and testosterone will obviously create imbalances and growth potential.  Fourth, how were the women evaluated prior to starting hormone therapy and then were they remonitered (unlikely), fifth, were hormone metabolites evaluated (too, also unlikely).  This study has serious flaws and very little can be extrapolated other than: don't take supra physiologic hormone levels without appropriate evaluation.  Enough said

Curcumin, best taken in form from Turmeric, found to significantly prevent diabetes progression and improve Beta islet cell function.  The dosage used in this 9 month trial was 1500 mg taken in divided dosing.  A major point is that turmeric actually improved pancreatic beta islet cell function and prevented Diabetes.  As "health" care providers our focus should be on prevention of disease.

Early estrogen therapy in perimenopause and early menopause, with Estradiol, provides more health benefits than later therapy.  This article looked at Estrogen's effects on a woman's brain.  This likely has its origins in the change in estrogen receptors. The signal is not changing, but the reception of that signal is.  How else can one explain a different response to the same hormone dosage?

Good article.  This article (case series) found that 40% of the men included had no increase in PSA with Testosterone.  One point on the Testosterone dosage is that they used androgen, which is an overdose of Testosterone.  That gives 60% that the PSA did increase.  These men had higher PSA to begin with which leads to the suggestion that the prostate cells were abnormal.  Those men that had a prostatectomy were more likely to have little if any increase in PSA.  This study did use a the 5 alpha reductase inhibitor dutasteride.

Review of the data points to poor quality of evidence dealing with DHEA in post-menopausal women with normal adrenal function.  Yet if DHEA is low, which is >95% produced by adrenals in women, then how can the adrenal function be "normal".   The meta-analysis found no improvement in libido and/or sexual function, and no improvement in lipids, glucose, weight... was noted.  Essentially not positive or negative effects were noted.  Abstract only available here, so dosage is a question.

An infusion pump quickens that process; by allowing you to use a digital keyboard to select the dosage of the infusion which is to be administered to a patient over time. After you have selected the correct dose, the infusion pump is going to automatically supply the patient with the appropriate medication.

decreased pitch is associated with increased dosage of Testosterone therapy in women.

DHEA reduces dosage of prednisone compared to placebo