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Nathan Goodyear

BMC Public Health | Abstract | High prevalence of vitamin D insufficiency and its assoc... - 0 views

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    Malaysians with metabolic syndrome and obesity found to have high prevalence of vitamin D insufficiency.  Role for vitamin D therapy for those with metabolic syndrome and obesity.
Nathan Goodyear

Vitamin D role and use in prediabetes. [Endocr Pract. 2010 May-Jun] - PubMed - NCBI - 0 views

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    vitamin D therapy shown to improve insulin resistance.  Vitamin D insufficiency (< 30 ng/ml) found in 77% of Americans
Nathan Goodyear

PLOS ONE: Vitamin D Supplementation and Breast Cancer Prevention: A Systematic Review a... - 0 views

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    Vitamin D supplementation finds no increased risk on breast cancer risk.  This is a negative study (meta-analysis) on vitamin D and breast cancer in postmenopausal women.  The strength of evidence lies with positive effects as numerous studies are documented in diigo here.
Nathan Goodyear

Restoration of regulatory and effector T cell balance and B cell homeostasis in systemi... - 0 views

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    Vitamin D support provides benefit in those with Lupus.  The proposed mechanism is through the balance of Treg cells and Th17 cells.  This imbalance plays a role in the etiology of autoimmune disease and those with autoimmune disease, such as in Lupus, frequently have low vitamin D levels.
Nathan Goodyear

Blood levels of vitamin D and early ... [Breast Cancer Res Treat. 2013] - PubMed - NCBI - 0 views

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    low vitamin D associated with breast cancer recurrence and mortality.
Nathan Goodyear

Testicular Synthesis and Vitamin D Action: The Journal of Clinical Endocrinology & Meta... - 0 views

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    Cholecalciferol (vitamin D3) was found to increase male Testosterone production in cell culture model.  This fits with other data that low vitamin D and low T often go hand in hand.  This study actually shows improved D levels increase Testicular Testosterone production, though in cell culture.
Nathan Goodyear

Effects of calcium-vitamin D co-supplementation... [Diabetologia. 2014] - PubMed - NCBI - 0 views

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    vitamin D plus calcium in those with Diabetes and low vitamin D four to improve insulin resistance, HDL, LDL, beta cell function, and HgbA1c.  This was a short course study of 8 weeks.  Only abstract available.
Nathan Goodyear

25-Hydroxyvitamin D, 1,25-Dihydroxyvitamin D and Postoperative Outcome in Cardiac Surge... - 0 views

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    low vitamin D predicts increased risk of Major adverse cardiac and/or cerebrovascular events after cardiac surgery.  The definition of low D was <30.  A better study would have been to stratify by 10s the risk.
Nathan Goodyear

Reduced expression of GDF-15 is associated with atrophic inflammatory lesions of the pr... - 0 views

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    Vitamin D again implicated in cancer.  This time prostate cancer.  Study found that vitamin D regulates the expression of GDF-15 which inhibits NF-kappaB.  Low vitamin D leads to decreased GDF-15 expression which leads to increased NF-kappaB transcription and resultant inflammation.
Nathan Goodyear

Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis - 0 views

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    High dose vitamin D (10,400 IU) found to reduce IL-17, CD161 and effector memory cells; in contrast low dose vitamin D (800 IU)  did not.  The study also called into question the traditional target range of vitamin D.  The authors here proposed 40-60
Nathan Goodyear

Vitamin D and Acute Myeloid Leukemia | IntechOpen - 0 views

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    low vitamin D associated with poor outcomes in hematologic cancers. This chapter reviews several studies that highlight the link with low vitamin D and poor outcomes in AML patients.
Nathan Goodyear

25-Hydroxyvitamin D, Parathyroid Hormone, and Mortality in Black and White Older Adults... - 0 views

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    low vitamin D and PTH in black and white elderly associated with increased mortality; however, the black elderly have lower vitamin D levels in comparison to their white counterparts.  How does this play a in increased advanced disease?  I believe quite a bit.
Nathan Goodyear

Vitamin D, Mitochondria, and Muscle - 0 views

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    editorial discussion of the benefit of vitamin D in mitochondrial function.   Those in the vitamin D repletion arm of the study had a quicker recovery time to restored phospho-creatinine levels.  The quicker the recovery of phospho-creatinine levels, the shorter recovery phase and the likely improvement in athletic performance.
Nathan Goodyear

Mounting Evidence for Vitamin D as an Environmental Factor Affecting Autoimmune Disease... - 0 views

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    low vitamin D associated with increase prevalence of autoimmune disease.
Nathan Goodyear

Vitamin D Deficiency Modulates Graves' Hyperthyroidism Induced in BALB/c Mice by Thyrot... - 0 views

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    Low vitamin D plays a role in immune response associated with Graves disease.  This study found small impact, but impact nonetheless.
Nathan Goodyear

Maternal 25-Hydroxyvitamin D and Preterm Birth in Twin Gesta... : Obstetrics & Gynecology - 0 views

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    vitamin D associated with increased Pre term delivery in twin pregnancies.  This is a cohort, so not the most reliable of study designs, but known that vitamin D inhibits inflammation and that this plays a role in labor...logic makes sense.
Nathan Goodyear

Preclinical Serum 25-Hydroxyvitamin D Levels and Risk of Type 1 Diabetes in a Cohort of... - 0 views

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    Increased type I DM in white military personal with low vitamin D.  The lower the vitamin D, the higher the risk.
Nathan Goodyear

Vitamin D status and breast cancer in Saudi Arabian women: case-control study - 0 views

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    Breast cancer inversely associated with vitamin D levels in Saudi Arabian women.  Invasive cancer also correlated with lower vitamin D levels.
Nathan Goodyear

PLOS Medicine: Causal Relationship between Obesity and Vitamin D Status: Bi-Directional... - 0 views

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    Study finds that obesity is linked to lower vitamin D.  Not that there is merely an association, but that the elevated BMI is the cause of lower vitamin D levels.
Nathan Goodyear

Serum vitamin D and sex hormones levels in men and women: The Multi-Ethnic Study of Ath... - 0 views

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    cross sectional study finds low vitamin D associated with a decrease in SHBG and an increase in free Testosterone;  a decrease in estradiol and an increase in DHEA was seen in women.  No association with total Testosterone was found.  There are studies that show a direct decrease in testicular Testosterone production in men with low vitamin D and decrease in AR function.
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