vitamin C therapy found to directly inhibit intracellular inflammatory signaling: TNF-alpha, IL-6. This was positively correlated with LPS stimulated inflammatory cytokines.
IV, high dose, vitamin C adjunct therapy shown to aid in the remission in to women with ovarian cancer. These two cases studies do only looked and high dose antioxidant therapy as an adjunct in ovarian cancer and they found good results.
high dose vitamin E and vitamin C are found to be safe. As always, the majority of these studies did not include pre-treatment vitamin assessment to ensure a metabolic need. To much of a good thing can be a bad thing. Also, higher dosing of vitamins approach a medicinal use and an associated increase in side effects.