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Nathan Goodyear

Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommend... - 0 views

www.ncbi.nlm.nih.gov/...PMC5725835

vitamin C deficiency hypovitaminosis C IV vitamin C septic shock critically ill hypovitaminosis ICU critical illness vitamin C critical care sepsis

shared by Nathan Goodyear on 14 Jul 22 - No Cached
  • Nathan Goodyear on 14 Jul 22
     
    Septic patients have lower vitamin C levels and respond less to typical dosing due to inflammaiton
Nathan Goodyear

Hypovitaminosis D is associated with insulin resistance and ß cell dysfunction - 0 views

www.ajcn.org/...820.full

vitamin D low hypovitaminosis insulin resistance

shared by Nathan Goodyear on 03 Sep 11 - No Cached
  • Nathan Goodyear on 03 Sep 11
     
    low Vitamin D associated with insulin resistance
Nathan Goodyear

Nutrients | Free Full-Text | Vitamin C Status Correlates with Markers of Metabolic and ... - 0 views

www.mdpi.com/...htm

vitamin C health cognition

shared by Nathan Goodyear on 28 Feb 18 - No Cached
  • vitamin C deficiency is the fourth most prevalent nutrient deficiency reported in the United States
  • Hypovitaminosis C (defined as a plasma concentration ≤23 µmol/L)
  • The CHALICE (Canterbury Health, Ageing and Lifecourse) study is a unique New Zealand study comprising a comprehensive database of determinants of health
  • ...17 more annotations...
  • The CHALICE cohort of 404 individuals aged 50 years had an average vitamin C intake of ~110 mg/day, which should provide adequate plasma concentrations [14]. Despite this, a significant proportion of the participants had inadequate plasma vitamin C status
  • inadequate plasma vitamin C concentrations (i.e., <50 µmol/L)
  • adequate plasma levels (i.e., >50 µmol/L)
  • Higher plasma vitamin C status was associated with lower weight, BMI and waist circumference
  • plasma vitamin C was negatively associated with blood triglycerides, HbA1c and insulin, and positively associated with HDL levels.
  • No correlation was found between plasma vitamin C and the two indicators of heart health; blood pressure and cardiovascular risk score.
  • 2.4% of 50-year-olds were deficient in vitamin C (i.e., <11 µmol/L)
  • hypovitaminosis C (i.e., <23 µmol/L)
  • A high proportion (63%) of our participants had inadequate plasma vitamin C concentrations (i.e., <50 µmol/L)
  • The association of low vitamin C with obesity in this study replicates results in the literature [35,40,41,42,43,44], and it is apparent that individuals with higher weight require higher intakes of vitamin C to reach adequate vitamin C status
  • higher plasma vitamin C status is associated with lower circulating levels of blood triglycerides, insulin and HbA1c
  • A role for vitamin C in the prevention or management of diabetes and/or metabolic syndrome has been suggested
  • In this study, we also demonstrate lower levels of mild cognitive impairment in those with high vitamin C status
  • The odds of mild cognitive impairment were twice as high for those below 23 μmol/L plasma vitamin C concentration.
  • Vitamin C is present at very high concentrations in the brain
  • animal models have shown that the brain is the last organ to be depleted of the vitamin during prolonged deficiency
  • A recent animal study has shown that moderate vitamin C deficiency may play a role in accelerating amyloid plaque accumulation in Alzheimer’s disease
  • Nathan Goodyear on 28 Feb 18
     
    New study: vitamin C levels correlate with cognitive and metabolic health. What is your vitamin C level? Despite the adequate levels of vitamin C intake, a large % of the individuals had inadequate vitamin C levels which points to a demand issue.  Higher oxidative stress, chronic inflammation... would drive demand for vitamin C higher. Lower vitamin C levels were associated with more metabolic disease, ie. DM, and more cognitive decline.
Nathan Goodyear

Hypovitaminosis C in hospitalized patients - ScienceDirect - 0 views

www.sciencedirect.com/...S0953620503001808

vitamin C deficiency hypovitaminosis hospital ascorbic acid vitamin C hospitalized patients

shared by Nathan Goodyear on 29 Jun 22 - No Cached
  • Nathan Goodyear on 29 Jun 22
     
    Hospitalized patients are depleted of vitamin C
Nathan Goodyear

Severe hypovitaminosis C in lung-cancer patients: the utilization of vitamin C in surgi... - 0 views

www.ncbi.nlm.nih.gov/...PMC2011112

ascorbic acid healing vitamin C surgery hypovitaminosis

shared by Nathan Goodyear on 29 Jun 22 - No Cached
  • Nathan Goodyear on 29 Jun 22
     
    Surgery depletes vitamin C which impairs repair. Nothing new in this topic, actually goes back decades.
Nathan Goodyear

Hypovitaminosis D and bone mineral m... [J Clin Densitom. 2010 Oct-Dec] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...20663698

vitamin D hyperthyroid HYPERTHYROIDISM bone

shared by Nathan Goodyear on 15 May 13 - No Cached
  • Nathan Goodyear on 15 May 13
     
    Hyperthyoid states found to be associated with low vitamin D.  The exact association is unknown.
Nathan Goodyear

Hypovitaminosis D in Patients Scheduled to Undergo Orthopaedic Surgery: A Single-Center... - 0 views

www.ejbjs.org/...2300

vitamin D deficiency

shared by Nathan Goodyear on 21 Jan 11 - No Cached
  • Given the importance of vitamin D in musculoskeletal health, such low levels may negatively impact patient outcomes.
  • Nathan Goodyear on 21 Jan 11
     
    Vitamin D deficiency slows orthopedic surgery healing
Nathan Goodyear

Association of hypovitaminosis D with metabolic disturbances in polycystic ovary syndrome - 0 views

www.eje-online.org/...575.short

vitamin D deficiency PCOS MetS metabolic syndrome

shared by Nathan Goodyear on 10 Sep 11 - No Cached
  • Nathan Goodyear on 10 Sep 11
     
    vitamin D deficiency associated with metabolic features in PCOS
Nathan Goodyear

Hypovitaminosis D is associated with insulin resistance and ß cell dysfunction - 0 views

www.ajcn.org/...820.long

vitamin D deficiency therapy insulin sensitivity

shared by Nathan Goodyear on 17 Sep 11 - No Cached
  • Nathan Goodyear on 17 Sep 11
     
    vitamin D therapy in those with low vitamin d improves insulin sensitivity by 60%.
Nathan Goodyear

The role of vitamin C in the treatment of pain: new insights - 0 views

www.ncbi.nlm.nih.gov/...PMC5391567

vitamin C pain arthritis

shared by Nathan Goodyear on 18 Sep 17 - No Cached
  • recommended that during illness one should be careful about the intake of vitamin C, keeping in mind that acute illness rapidly depletes stores of ascorbic acid
  • it is possible that other hospital-associated pain may be partly due to vitamin C deficiency, which is relatively prevalent in hospital settings
  • Vitamin C deficiency (defined as plasma vitamin C concentrations <11 µmol/L
  • ...5 more annotations...
  • Vitamin C is cost effective and appears to be a safe and effective adjunctive therapy for specific pain relief
  • it decreases the requirement for opioid analgesics, particularly post surgically and for bone metastasis
  • recent research has indicated a positive impact of high dose vitamin C on cancer- and chemotherapy-related quality of life, including pain
  • Cameron and Campbell [81] reported a number of cases of dramatic to complete amelioration of bone pain in patients with severe cancer-related pain given both high dose oral and intravenous vitamin C
  • hypovitaminosis C (defined as plasma vitamin C concentrations <23 µmol/L
  • Nathan Goodyear on 18 Sep 17
     
    vitamin C reduces pain; mechanism of action likely anti-inflammatory antioxidant, but yet inconclusive.
Nathan Goodyear

Global Vitamin C Status and Prevalence of Deficiency: A Cause for Concern? - PMC - 0 views

www.ncbi.nlm.nih.gov/...PMC7400810

hypovitaminosis vitamin C global vitamin C deficiency worldwide ascorbic acid

shared by Nathan Goodyear on 29 Jun 22 - No Cached
  • rsf123 on 01 Jul 22
     
    Vitamin levels decreased in the critically ill. https://t.me/amsterdamdarkmarket
Nathan Goodyear

Vitamin C deficiency in a university teaching hospital - PubMed - 0 views

pubmed.ncbi.nlm.nih.gov/18838532

ascorbic acid hospitalized patients hypovitaminosis hospital vitamin C deficiency hospitals vitamin C

shared by Nathan Goodyear on 29 Jun 22 - No Cached
  • Nathan Goodyear on 29 Jun 22
     
    60% of hospitalized patients had a subnormal vitamin C concentration and 19% were deficient
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