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Nathan Goodyear

Frontiers | Microbiome-Derived Lipopolysaccharide Enriched in the Perinuclear Region of... - 0 views

journal.frontiersin.org/...full

LPS lipopolysaccharides Alzheimer's disease brain inflammation

shared by Nathan Goodyear on 23 Sep 17 - No Cached
  • lipopolysaccharides (LPS), either alone or in combination, have indicated that when compared, bacterial LPSs exhibit the strongest induction of pro-inflammatory signaling in human neuronal–glial cells in primary coculture of any single inducer, and different LPS extracts from different gastrointestinal (GI)-tract resident Gram-negative bacteria appeared to have different pro-inflammatory potential
  • powerful inducer of the NF-κB
  • In both neocortex and hippocampus, LPS has been detected to range from a ~7- to ~21-fold increase abundance in AD brain
  • ...15 more annotations...
  • Major Gram-negative bacilli of the human GI-tract, such as the abundant B. fragilis and Escherichia coli (E. coli), are capable of discharging a remarkably complex assortment of pro-inflammatory neurotoxins
  • (i) bacterial amyloids (10, 21); (ii) endotoxins and exotoxins (5, 12); (iii) LPS (12, 18); and (iv) small non-coding RNAs (sncRNAs)
  • integral components of the outer leaflet of the outer membrane of Gram-negative bacteria, LPS
  • LPS, the major molecular component of the outer membrane of Gram-negative bacteria normally serves as a physical barrier providing the bacteria protection from its surroundings
  • LPS is also recognized by the immune system as a marker for the detection of bacterial pathogen invasion and responsible for the development of inflammatory response is perhaps the most potent stimulator and trigger of inflammation known
  • AD-affected brains have remarkably large loads of bacterial-derived toxins compared to controls. The transfer of noxious, pro-inflammatory molecules from the GI-tract microbiome to the CNS may be increasingly important during the course of aging when both the GI-tract and blood–brain barriers become significantly more permeable
  • first evidence of a perinuclear association of LPS with AD brain cell nuclei
  • LPS-mediated stimulation of chronic inflammation, beta-amyloid accumulation, and episodic memory decline in murine models of AD (39, 40) and a biophysical association of LPS with amyloid deposits and blood vessels in human AD patients
  • Strong adherence of LPS to the nuclear periphery has recently been shown to inhibit nuclear maturation and function that may impair or block export of mRNA signals from brain cell nuclei, a highly active organelle with extremely high rates of transcription, mRNA processing, and export into the cytoplasm
  • LPS may be further injurious to the nuclear membrane just as LPS contributes to cerebrovascular endothelial cell membrane injury
  • high intake of dietary fiber is a strong inhibitor of B. fragilis abundance and proliferation in the intact human GI-tract and as such is a potent inhibitor of the neurotoxic B. fragilis-derived amyloids, LPS, enterotoxins, and sncRNAs.
  • GI-tract microbiome-derived LPS may be an important initiator and/or significant contributor to inflammatory degeneration in the AD CNS
  • LPS has been recently localized to the same anatomical regions involved in AD-type neuropathology
  • a known pro-inflammatory transcription factor complex that triggers the expression of pathogenic pathways involved in neurodegenerative inflammation
  • pro-inflammatory amyloids, endo- and exotoxins, LPSs, and sncRNAs but also serve as potent sources of membrane-disrupting agents
  • Nathan Goodyear on 23 Sep 17
     
    LPS links gut to inflammation in Alzheimer's disease
wheelchairindia9

Reclining Commode Wheelchair - 0 views

www.wheelchairindia.com/...Reclining-Wheelchair-609-GC

High Back Reclining Wheelchair For Handicapped foot rests and backrest handbrake-like controls incremental angles safely comfort and health benefits padded arm rests

shared by wheelchairindia9 on 05 May 15 - No Cached
  • wheelchairindia9 on 05 May 15
     
    wheelchair category (standard, transport, power, etc.) could be classified as a reclining wheelchairs, since the product class is built around one key feature: the capability to adjust the backrest and/or footrest into a reclined position. This feature is especially important to users who find it difficult or impossible to sit in a fully upright position, and users who sleep in their chairs frequently. For those that are looking for a more portable chair, however, products from this category may not be a great fit. When compared with a similar, non-reclining chair, a reclining wheelchair tends to weigh more and - unlike other manual models - manual wheelchairs that recline typically aren't foldable. Some people use special wheelchairs to distribute pressure and thus reduce the risk of skin sores. These chairs also increase comfort and sitting tolerance. One type of chair, called "tilt in space," changes a person's orientation while maintaining fixed hip, knee, and ankle angles. The whole seat, in effect, tilts. The other chair option is called a recline system, which basically changes the seat-to-back angle, flattening out the back of the chair and in some cases raising the legs to form a flat surface. Different Types Of Reclining Wheelchairs: Reclining Wheelchair 902 GC Reclining Wheelchair 609 GC Karma Aurora 4 Reclining Wheelchair Karma Reclining Wheelchair KM 5000 Karma VIP 515 Wheelchair Reclining Wheelchair 902 GC: Reclining Wheelchair 902 GC is one of the basic models of a Reclining Wheelchair which helps transfer to bed to wheelchair easily and comes with head and neck support and Calf support for added comfort. Reclining Wheelchair 902 GC Features: The chair boast of movable armrest and elevating footrest. A well padded thigh support helps the user thigh's during reclining. The front and the rear wheels are designed and placed in such a way so as to support the users weight during reclining. The Pneumatic rear wheels help the movement
wheelchairindia9

Reclining Commode Wheelchair - 0 views

disabilityproduct.in/...Reclining-Wheelchair-609-GC

Disability Seating And Tilt-In-Space Wheelchair adjustable seat height and depth systems provide added comfort neck and trunk a much-needed break wheelchair provides a sole pivot point movable armrest and elevating footrest

shared by wheelchairindia9 on 25 Aug 15 - No Cached
  • wheelchairindia9 on 25 Aug 15
     
    Reclining Wheelchair 609 GC Reclining Wheelchair 609 GC is one of the multipurpose chairs which boast of features like reclining, inbuilt commode, customized armrest and footrest and foldable nature of the chair. Reclining Wheelchair 609 GC Features The wheelchair can be folded within very easily within seconds, making it easier during travels and outings. The backrest of the chair can be easily reclined, giving the user the freedom to relax by not moving up from the chair. The footrest can be inclined and adjusted so as to make the user comfortable during reclining or otherwise. A well paded thigh support is an add-on to the footrest. The front and rear wheels of the chair are designed and placed in such a way so as to support the reclining of the user, making it a very safe and friendly wheelchair. The inbuilt commode has its seat just underneath the main seat of the chair; it can be used by just removing the main seat. The Wheelchair can also be folded from between by just removing the commode and the chair's seat. This Wheelchair's functionality gives the user total freedom. Easy to fold and unfold within seconds. Reclining Wheelchair 609 GC Measurements Frame Style : Foldable Frame Material : MS Chrome Plated open position wheel to wheel width in : 26" (inches) Seat Width : 18" (inches) Total width in closing position : 11" (inches) Rear Wheel Size : 24" (inches) Front Wheel Size : 8" (inches) Seat to Floor Height in : 21" (inches) Seat Depth : 18" (inches) Total Height : 50" (inches) Max User Weight Capacity (kgs) : 110 Net Weight (kgs) : 23 Upholstery : Rexine Armrest : Detachable Leg rest : Detachable with elevated footrest Calf support for added comfort Wheel Quality : Rear Solid wheels Rear Wheel Lock : Yes Hand Brakes : No Drop back Handle : No Headrest Support Available Neck Support Available Plastic Commode seat with Pot. Cushioned Top Cover Rear tyer Solid tube less Round commode pan Removabl
wheelchairindia9

Karma Km 5000 Wheelchair - 0 views

disabilityproduct.in/...a-Reclining-Wheelchair-KM-5000

Disability Seating And Tilt-In-Space Wheelchair adjustable seat height and depth systems provide added comfort neck and trunk a much-needed break wheelchair provides a sole pivot point movable armrest and elevating footrest

shared by wheelchairindia9 on 21 Aug 15 - No Cached
  • wheelchairindia9 on 21 Aug 15
     
    Karma Reclining Wheelchair KM 5000 The karma reclining wheelchair km-5000 Transport Wheelchair is an ultra lightweight folding aluminum reclining wheelchair. With full length padded armrests, an adjustable height head pillow, and more this wheelchair has added comfort for any user. This chair also features swing-away elevating footrests and adjustable length leg supports and footplates. With a weight of 33 Lbs this chair can be transported with ease. Karma Reclining Wheelchair KM 5000 Features Folding 6061 T-6 Aircraft-grade aluminum frame in black powder coat finish Backrest Reclines 90°~163° and includes anti-tippers Full length padded detachable armrests with side panels Swing-away detachable elevating footrests Adjustable length leg supports & footplates Adjustable-height head pillow 14" Mag wheels with flat free polyurethane tires 7" x 1" Flat free front polyurethane casters Adjustable toggle wheel locks High-grade flame retardant, breathable nylon upholstery Limited lifetime warranty on frames and cross-braces, one year on parts One of only two lightweight recliners available in the USA Also Available in Large Manual Rear Wheel option, (KM- 5000F), please call for more info Frame Color: Silver WARRANTY 1 Year Karma Reclining Wheelchair KM 5000 Measurements Seat Width 18 inch. Seat Depth 18 inch. Seat Height 20 inch. Back Height 33 inch. Overall Height 51 inch. Overall Open Width 25 inch., 27 inch., 29 inch., 31 inch. Overall Length 39 inch. Weight Without Riggings 33 lb., 34 lb. Weight Cap 250 lb., 300 lb., 350 lb. Shipping Dimensions 39? L x 30? H x 14? W
Nathan Goodyear

Selenomethionine and α-Tocopherol Do Not Inhibit Prostate Carcinogenesis in t... - 0 views

cancerpreventionresearch.aacrjournals.org/...371.long

prostate cancer prostate cancer estrogen estradiol male hormones

shared by Nathan Goodyear on 18 Nov 16 - No Cached
  • Nathan Goodyear on 18 Nov 16
     
    In this animal study, estradiol is added to Testosterone to increase prostate carcinogenesis.  Previous rat studies have shown that adding estradiol to Testosterone, which occurs naturally, increases prostate cancer risk.  
Nathan Goodyear

JISSN | Full text | International Society of Sports Nutrition position stand: creatine ... - 0 views

www.jissn.com/6

creatine sports nutrition exercise

shared by Nathan Goodyear on 27 Jan 14 - No Cached
  • the energy supplied to rephosphorylate adenosine diphosphate (ADP) to adenosine triphosphate (ATP) during and following intense exercise is largely dependent on the amount of phosphocreatine (PCr) stored in the muscle
  • Creatine is chemically known as a non-protein nitrogen
  • It is synthesized in the liver and pancreas from the amino acids arginine, glycine, and methionine
  • ...26 more annotations...
  • Approximately 95% of the body's creatine is stored in skeletal muscle
  • About two thirds of the creatine found in skeletal muscle is stored as phosphocreatine (PCr) while the remaining amount of creatine is stored as free creatine
  • The body breaks down about 1 – 2% of the creatine pool per day (about 1–2 grams/day) into creatinine in the skeletal muscle
  • The magnitude of the increase in skeletal muscle creatine content is important because studies have reported performance changes to be correlated to this increase
  • "loading" protocol. This protocol is characterized by ingesting approximately 0.3 grams/kg/day of CM for 5 – 7 days (e.g., ≃5 grams taken four times per day) and 3–5 grams/day thereafter [18,22]. Research has shown a 10–40% increase in muscle creatine and PCr stores using this protocol
  • Additional research has reported that the loading protocol may only need to be 2–3 days in length to be beneficial, particularly if the ingestion coincides with protein and/or carbohydrate
  • A few studies have reported protocols with no loading period to be sufficient for increasing muscle creatine (3 g/d for 28 days)
  • Cycling protocols involve the consumption of "loading" doses for 3–5 days every 3 to 4 weeks
  • Most of these forms of creatine have been reported to be no better than traditional CM in terms of increasing strength or performance
  • Recent studies do suggest, however, that adding β-alanine to CM may produce greater effects than CM alone
  • These investigations indicate that the combination may have greater effects on strength, lean mass, and body fat percentage; in addition to delaying neuromuscular fatigue
  • creatine phosphate has been reported to be as effective as CM at improving LBM and strength
  • Green et al. [24] reported that adding 93 g of carbohydrate to 5 g of CM increased total muscle creatine by 60%
  • Steenge et al. [23] reported that adding 47 g of carbohydrate and 50 g of protein to CM was as effective at promoting muscle retention of creatine as adding 96 g of carbohydrate.
  • It appears that combining CM with carbohydrate or carbohydrate and protein produces optimal results
  • Studies suggest that increasing skeletal muscle creatine uptake may enhance the benefits of training
  • Nearly 70% of these studies have reported a significant improvement in exercise capacity,
  • Long-term CM supplementation appears to enhance the overall quality of training, leading to 5 to 15% greater gains in strength and performance
  • Nearly all studies indicate that "proper" CM supplementation increases body mass by about 1 to 2 kg in the first week of loading
  • short-term adaptations reported from CM supplementation include increased cycling power, total work performed on the bench press and jump squat, as well as improved sport performance in sprinting, swimming, and soccer
  • Long-term adaptations when combining CM supplementation with training include increased muscle creatine and PCr content, lean body mass, strength, sprint performance, power, rate of force development, and muscle diameter
  • subjects taking CM typically gain about twice as much body mass and/or fat free mass (i.e., an extra 2 to 4 pounds of muscle mass during 4 to 12 weeks of training) than subjects taking a placebo
  • The gains in muscle mass appear to be a result of an improved ability to perform high-intensity exercise via increased PCr availability and enhanced ATP synthesis, thereby enabling an athlete to train harder
  • there is no evidence to support the notion that normal creatine intakes (< 25 g/d) in healthy adults cause renal dysfunction
  • no long-term side effects have been observed in athletes (up to 5 years),
  • One cohort of patients taking 1.5 – 3 grams/day of CM has been monitored since 1981 with no significant side effects
  • Nathan Goodyear on 27 Jan 14
     
    Nice review of the data, up to the publication date, on creatine.
wheelchairindia9

Recliner Wheelchair - 0 views

www.wheelchairindia.com/...RECLINING-WHEELCHAIR

Prepare Complete Flexibility With Reclining Wheelchair positioned for maximum comfort available in foldable frames reclining under desks legs and feet can also be re-positioned extended head supports and seat using high quality material

shared by wheelchairindia9 on 20 May 15 - No Cached
  • wheelchairindia9 on 20 May 15
     
    Reclining wheelchairs, since the product class is built around one key feature: the capability to adjust the backrest and/or footrest into a reclined position. This feature is especially important to users who find it difficult or impossible to sit in a fully upright position, and users who sleep in their chairs frequently. For those that are looking for a more portable chair. When compared with a similar, non-reclining chair, a reclining wheelchair tends to weigh more and - unlike other manual models - manual wheelchairs that recline typically aren't foldable. reclining wheelchair compensates mechanically for body positioning by automatically readjusting armrests and lateral supports.

    Recliner wheelchair is low profile allowing to comfortably fit under tables and desks. Enjoy numerous activities with increased comfort such as stretching, napping and watching television. The ability to recline also improves circulation and the ability for sore spots to heal.

    Karma Reclining Wheelchair KM 5000:
    The karma reclining wheelchair km-5000 Transport Wheelchair is an ultra lightweight folding aluminum reclining wheelchair. With full length padded armrests, an adjustable height head pillow, and more this wheelchair has added comfort for any user. This chair also features swing-away elevating footrests and adjustable length leg supports and footplates. With a weight of 33 Lbs this chair can be transported with ease.

    Karma Reclining Wheelchair KM 5000 Features:
    Folding 6061 T-6 Aircraft-grade aluminum frame in black
    powder coat finish
    Backrest Reclines 90°~163° and includes anti-tippers
    Full length padded detachable armrests with side panels
    Swing-away detachable elevating footrests
    Adjustable length leg supports & footplates
    Adjustable-height head pillow
    14" Mag wheels with flat free polyurethane tires
    7" x 1" Flat free front polyurethane casters
    Adjustab
pharmacybiz

DHSC adds Dexcom One transmitter to March 2023 Drug Tariff - 0 views

www.pharmacy.biz/tter-to-march-2023-drug-tariff

dexcom-one-transmitter-drug-tariff dexcom-one-transmitter-uk pharmacy-business Dexcom-ONE-transmitter-NHS dexcom-one-transmitter-prescription how-much-does-dexcom-transmitter-cost

shared by pharmacybiz on 11 Feb 23 - No Cached
  • pharmacybiz on 11 Feb 23
     
    Department of Health of Social Care (DHSC) has confirmed that the Dexcom One Transmitter will be added to Part IXA of the March 2023 Drug Tariff. "Previously, patients were advised to obtain the free-of-charge Dexcom One transmitters directly from the pharmacies, without a prescription, as the original Drug Tariff application for the transmitter was unsuccessful," said the Pharmaceutical Services Negotiating Committee (PSNC) It has raised concerns with DHSC and Dexcom that these distribution arrangements for transmitters are unacceptable because they result in extra unfunded activity for community pharmacies. Both, DHSC and Dexcom acted upon these concerns by agreeing to add the Dexcom One transmitter to the Drug Tariff from March 2023. At the same time, Dexcom One CGM System (containing 1 sensor, 1 sensor applicator, 1 transmitter) will also be added to the March Drug Tariff.
Windows Customer Support Number

Windows technical support number 1-800-261-4071 - 0 views

sanjoseca.global-free-classified-ads.com/...-1-800-261-4071-it6632225.html

Windows technical customer services tech help support

shared by Windows Customer Support Number on 16 Jul 16 - No Cached
  • Windows Customer Support Number on 16 Jul 16
     
    Windows technical support number 1-800-261-4071 (, ) - Free Classified ads. For a moment answers for all Windows programming inquiries, converse with our professionals by dialing Our Windows technical support number 1-800-261-4071, we work at all day, every day premise,
Nathan Goodyear

JAMA Network | Archives of Neurology | Neuronal Cyclooxygenase 2 Expression in the Hipp... - 0 views

archneur.jamanetwork.com/article.aspx

COX-2 inflammation dementia AD Alzheimer's disease neurology brain

shared by Nathan Goodyear on 11 Jun 12 - No Cached
  • Nathan Goodyear on 11 Jun 12
     
    COX-2 expression associated with increasing dementia in AD.
Nathan Goodyear

Inflammatory Mechanisms in Alzheimer's Disease: Inhibition of β-Amyloid-Stimu... - 0 views

www.jneurosci.org/...558.long

inflammation AD alzheimer's neurodegenerative disease PPAR-gamma PPAR microglial alzheimer

shared by Nathan Goodyear on 11 Jun 12 - No Cached
  • PPARγ agonists were shown to inhibit the β-amyloid-stimulated expression of the cytokine genes interleukin-6 and tumor necrosis factor α. Furthermore, PPARγ agonists inhibited the expression of cyclooxygenase-2.
  • Nathan Goodyear on 11 Jun 12
     
    Not that we are recommending NSAIDS to reduce inflammation: but the learned biochemical pathways of inflammation involved with AD, allows a natural approach to reduce microglial associated inflammation through PPAR-gamma activation.
wheelchairindia9

Karma Aurora 4 - 0 views

disabilityproduct.in/...-Aurora-4-Reclining-Wheelchair

Karma Aurora 4 Reclining Wheelchair Detachable with calf support for added comfort Hand brakes Fordable Karma Aurora 4

shared by wheelchairindia9 on 11 Sep 15 - No Cached
  • wheelchairindia9 on 11 Sep 15
     
    Karma Aurora 4 Reclining Wheelchair Frame Style : Fordable Frame Material : Aluminium (Light weight) Seat Width (inches) : 18" Total width in wheel to wheel : 11" Rear Wheel Size : 24" Front Wheel Size : 7" Seat to floor height (inches) : 20" Seat Depth (inches) : 16" Back height (inches) : 35" Total height (inches) : 50" Max User Weight Capacity (kgs) : 120 Frame Net Weight (kgs) : 13.5 k.g. Upholstery : Cloth water-proof. Armrest : Detachable, for easy transfer to bed. Leg-rest : Detachable, can also be elevated & with calf support for added comfort Wheel Quality : MAG WHEEL Rear Wheel Brakes : Available Hand brakes : Available
Nathan Goodyear

The Relationship between Alzheimer's Disease and Diabetes: Type 3 Diabetes? - ACAM Inte... - 0 views

acam.typepad.com/...diabetes-type-3-diabetes-.html

Diabetes Insulin Glucose Alzheimer's disease metabolic syndrome

shared by Nathan Goodyear on 17 Mar 11 - No Cached
  • AD has its foundation in neuroendocrinology
  • Referring to AD as type 3 diabetes has its foundation in the fact that the CNS in AD is characterized by a paucity of insulin and resistance of the insulin receptors
  • Nathan Goodyear on 17 Mar 11
     
    Insulin/Glucose dysregulation and Alzheimer's disease
Nathan Goodyear

Indoleamine 2,3 dioxygenase and quinolinic acid im... [Neuropathol Appl Neurobiol. 2005... - 0 views

www.ncbi.nlm.nih.gov/...16008823

indoleamine 2 3 Alzheimer's disease inflammation

shared by Nathan Goodyear on 20 Apr 11 - No Cached
  • kynurenine pathway is up-regulated in Alzheimer's disease (AD) brain
  • increases in the excitotoxin quinolinic acid (QUIN
  • indoleamine 2,3 dioxygenase (IDO) is abundant in AD compared with controls
  • ...1 more annotation...
  • QUIN may be involved in the complex and multifactorial cascade leading to neuro-degeneration in AD
  • Nathan Goodyear on 20 Apr 11
     
    immune system, inflammation, and brain come together to develop Alzheimer's disease
wheelchairindia9

Easy Frame Size Adjustment On Karma Wheelchair - 0 views

onlywheelchair.blogspot.in/...-size-adjustment-on-karma.html

Easy Frame Size Adjustment On Karma Wheelchair Karma KM 2500 Wheelchair padded-permanent armrests Karma KM 2500 added truck support and positioning KM 2500 Wheelchair caregiver can easily push

shared by wheelchairindia9 on 05 Nov 15 - No Cached
  • wheelchairindia9 on 05 Nov 15
     
    Utilizing small wheels and lighter materials, transport wheelchairs can tip the scale at as little as 19 lbs., ideal for those looking for a highly portable option. Transport chairs also tend to be more affordable and offer the benefit of increased mobility without breaking the bank. This type of lightweight wheelchair is often referred to as a "transfer chair" and is typically used for shorter trips. Since it's geared towards storability and portability, it features four smaller wheels and dispenses with the larger, rear-mounted wheels that characterize standard wheelchairs. Its construction ensures that it's always foldable and portable, but does so at the expense of self-propulsion. Instead, a transport chair is built so that a caregiver can easily push the user from point A to B. Transport Wheelchair features a lightweight aluminum frame with a multiple finish options. It comes standard with padded-permanent armrests and swing-away footrests with composite footplates. It is an ideal solution for easy transportation and storage. Karma KM 2500 Small Wheel Wheelchair: Karma KM 2500 Small Wheel Wheelchair Specifications: Width 18" Front/Rear Wheels 6" to 14" Seat Width 47cm Seat Depth 40cm Overall Width 66cm Overall Collapsed Width 36cm Armrest Height 21cm Overall Length 90cm Seat Height 47cm Backrest Height 38cm Overall Height 86cm Weight 9.2 k.g. Karma KM 2500 Small Wheel Wheelchair Seat and Back: AEGIS Microbe Shield Approved by the FDA, EPA, EU, etc., bonded anti-microbial barrier upholstery protects from odor, staining and deterioration from bacteria, fungus and other microorganisms. It is a shield for your health. Karma KM 2500 Small Wheel Wheelchair Extended Armrest: By simulating the natural position of arms, the extended armrest design is ergonomic and creates bigger seating space. An Ultra lightweight wheelchair (9.2 kg) with a compact design for either attendant assisted or self propelling users. The
Nathan Goodyear

Alzheimer's Disease Clinical and Research Update for Health Care Practitioners - 0 views

www.ncbi.nlm.nih.gov/...PMC3776389

Alzheimer's disease cognition memory Alzheimers brain brain health alpha-GPC phosphatidyl serine Huperzine A choline

shared by Nathan Goodyear on 26 Sep 17 - No Cached
  • Alpha GPC, phosphatidylserine, Huperzine A, and choline show promise as nutraceutical agents for enhancing cognitive performance and slowing cognitive decline
  • Alpha GPC, also known as L-Alpha Glycerylphosphorylcholine, a naturally occurring form of choline, acts as a parasympathomimetic acetylcholine precursor and has shown promise in improving cognitive symptoms related to AD, vascular dementia, and multi-infarct dementia
  • Phosphatidylserine is a widely abundant anionic phospholipid in the human body and has been shown to improve age-related cognitive changes
  • ...2 more annotations...
  • Huperzine A (a natural cholinesterase inhibitor) has been linked to improved memory performance in elderly people with benign forgetfulness, as well as patients with AD and vascular dementia
  • Cholinesterase inhibitors have been shown to have neuroprotective properties in patients with mild [37] as well as moderate-to-advanced AD
  • Nathan Goodyear on 26 Sep 17
     
    good review of treatment for Alzheimer's, both prescription and natural.
Nathan Goodyear

International Journal of Obesity - Late-life obesity is associated with smaller global ... - 1 views

www.nature.com/...ijo201213a.html

obese obesity overweight gray matter brain

shared by Nathan Goodyear on 22 Feb 13 - No Cached
  • Nathan Goodyear on 22 Feb 13
     
    obese have smaller grey matter in the brain.  Remember the old ad, "this is your brain on drugs".  Well, this is your brain when fat...smaller.
Nathan Goodyear

Frontiers | Adherence to a Mediterranean-Style Diet and Effects on Cognition in Adults:... - 0 views

journal.frontiersin.org/...full

nutrition diet mediterranean diet brain alzheimer's disease Alzheimers memory

shared by Nathan Goodyear on 26 Sep 16 - No Cached
  • adherence to a MedDiet pattern is associated with less cognitive decline, dementia, or AD
  • higher adherence to a MedDiet was related to either slowing the rate of cognitive decline, minimizing the conversion to AD or improving the cognitive function
  • The more specific cognitive domains that improved with MedDietS were memory, delayed recognition, executive function, long-term working memory, and visual constructs
  • Nathan Goodyear on 26 Sep 16
     
    Mediterranean diet found to improve cognition and slow progression and/or risk of Alzheimer's disease.
Nathan Goodyear

Induction at high incidence of ductal prostate adenocarcinomas in NBL/Cr and Sprague-Da... - 0 views

www.ncbi.nlm.nih.gov/...7788848

prostate prostate cancer estrogen men estradiol male hormones Testosterone hormones

shared by Nathan Goodyear on 18 Nov 16 - No Cached
  • Nathan Goodyear on 18 Nov 16
     
    Adding Estradiol to Testosterone in rate model significantly increases prostate carcinogenesis in rat model.
Nathan Goodyear

Effects of green tea catechins and... [BMC Complement Altern Med. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...21338496

green tea EGCG flu influenza prevention prophylaxis

shared by Nathan Goodyear on 22 Nov 11 - No Cached
  • Nathan Goodyear on 22 Nov 11
     
    green tea shown to reduce incidence of flu by 83%. L-theanine was added to this mix.  This was found in healthcare workers, where one can imagine the exposure would be very high.
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