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Nathan Goodyear

Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppresses tumo... - 0 views

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    Boswellia shown to stimulate human breast cancer cell death.
Nathan Goodyear

Breast cancer mortality trends in England and the assessment of the effectiveness of ma... - 0 views

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    40 year study out of England finds no mortality benefit from mammograms screening.
Nathan Goodyear

Effects of alpha-lipoic acid on cell prolifer... [Nutr Res Pract. 2009] - PubMed - NCBI - 0 views

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    alpha lipoic acid inhibits cell growth and induces apoptosis in breast cancer cell lines.
Nathan Goodyear

Less Invasive Treatment is Associated with Improved Survival in Early Stage Breast Canc... - 0 views

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    better survival with lumpectomy and radiation versus mastectomy for early stage breast cancer.
Nathan Goodyear

Vitamin D status and breast cancer in Saudi Arabian women: case-control study - 0 views

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    Breast cancer inversely associated with vitamin D levels in Saudi Arabian women.  Invasive cancer also correlated with lower vitamin D levels.
Nathan Goodyear

Intake of fish and marine n-3 polyunsaturated fatty acids and risk of breast cancer: me... - 0 views

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    Omega 3 associated with decrease Breast cancer risk in women.
hadiyasafdar

10 Things I wish I'd known before Breast Augmentation - 0 views

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    Breast augmentation procedure is designed to enhance the size and fullness of the breasts, usually with breast implants. If you are unhappy with the appearance of your breasts because they are smaller in size or they have lost their volume or shape due to pregnancy or rapid weight fluctuations, you might consider a breast augmentation to get the breasts of your desire.
Nathan Goodyear

Dietary glycemic index and glycemic load and breast cancer risk in the European Prospec... - 0 views

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    high carbohydrate intake associated with increased risk of ER/PR negative breast cancer in Postmenopausal women.
Nathan Goodyear

The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice ... - 0 views

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    NF-kappaB and the associated inflammatory pathways are associated with tumor growth, vascular growth within the tumor, and increased migration of macrophages--thus more inflammation.  When NF-kappaB inhibition was achieved, tumor macrophages and new tumor blood vessel growth was decreased.  Reduced blood vessel growth to the tumor has implications on metastasis of the tumor.
Nathan Goodyear

Cruciferous Vegetable Consumption Linked to Improved Breast Cancer Survival Rates - 0 views

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    higher cruciferous vegetable intake associated with improved breast cancer survival rates according to Shanghai Breast Cancer Survival Study.
Nathan Goodyear

Association of Leukocyte Telomere Length With Breast Cancer Risk: Nested Case-Control F... - 0 views

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    Shorter telomere lengths associated with breast cancer.  But, longer telomere length may as well.
Nathan Goodyear

Serum progesterone and prognosis in operable breast cancer. - 0 views

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    progesterone levels at the time of surgery predict outcome.  Higher progesterone levels associated with increased longevity.  progesterone > 4 ng/ml associated with 65% survival at 18 years versus 35% with those women and low progesterone.
Nathan Goodyear

Steroid Hormone Levels during Pregnancy and Incidence of Maternal Breast Cancer - 0 views

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    Women with the highest progesterone levels during pregnancy have an inverse low breast cancer risk.  This association was found with premenopausal breast cancer.  The reduction was upwards of 70%.  One fault of this study is the use of serum hormone levels.  
Nathan Goodyear

BREAST CANCER INCIDENCE IN WOMEN WITH A HISTORY OF PROGESTERONE DEFICIENCY - 0 views

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    Women with low progesterone have 5.4 x elevated risk of premenopausal breast cancer.  This was a study done on women seeking fertility.  This study followed women for 33 years.
Nathan Goodyear

The impact of vitamin D in breast cancer: genomics, pathways, metabolism - 0 views

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    Good review article of how vitamin D interacts with the biochemistry of breast cancer.
Nathan Goodyear

Weight gain after primary surgery fo... [Breast Cancer Res Treat. 1992] - PubMed - NCBI - 0 views

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    The increased weight with tamoxifen is seen premenopausal women, but less with postmenopausal women.
Nathan Goodyear

Estrogen Metabolism and Risk of Breast Cancer in Postmenopausal Women - 0 views

  • The ratio of the 2-hydroxylation pathway to parent estrogens was associated with a statistically significantly decreased risk of breast cancer
  • In this study, this ratio was more strongly associated with the risk of breast cancer compared with the ratio of 2-hydroxylation pathway to 16-hydroxylation pathway or unconjugated estradiol alone
  • 2-hydroxylation pathway catechols have relatively low affinities for estrogen receptors (4) and are rapidly cleared from circulation
  • ...6 more annotations...
  • In this study, the ratio of the 2-hydroxylation pathway to the 16-hydroxylation pathway was associated with a non-statistically significantly decreased risk of breast cancer
  • In this study, the ratio of catechols to methylated catechols in the 4-hydroxylation pathway was associated with statistically significantly increased risk of breast cancer.
  • This result is consistent with the hypothesis that mutagenic quinones derived from 4-hydroxylation pathway catechols contribute to pathogenesis of postmenopausal breast cancer.
  • Catechols in both the 2- and 4-hydroxylation pathways can be oxidized to form quinones; these reactive electrophiles can then react with DNA to form a variety of adducts
  • Methylation of the catechols prevents their conversion to reactive quinones
  • the most common DNA adducts derived from 4-hydroxylation pathway catechols are depurinating and highly mutagenic (7,40), most of those derived from 2-hydroxylation pathway catechols are stable and can be repaired with little error
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    Lower 2-OH estrone metabolism associated with lower risk of breast cancer, but 4-OH estrone associated with increased risk of breast cancer.
Nathan Goodyear

Cannabidiol Induces Programmed Cell Death in Breast Cancer Cells by Coordinating the Cr... - 0 views

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    Cannabidiol (CBD) induces cancer cell apoptosis in human cell culture.
Nathan Goodyear

The Peripheral Blood Neutrophil-To-Lymphocyte Ratio Is Superior to the Lymphocyte-To-Mo... - 0 views

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    Neutrophil:Lymphocyte ratio more valuable than LMR in TNBC
Nathan Goodyear

Synergistic anticancer action of quercetin and curcumin against triple-negative breast ... - 0 views

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    Must read of the synergistic effects of quercetin and curcumin in TNBC.
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