Thyroid Hormones (T3 and T4): Dual Effect on Human Cancer Cell Proliferation - 0 views
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The effects of T3 on cancer cell lines varies. All cell lines came from the same tissue. It doesn't appear that simply stating T3 promotes cellular metabolism and thus provides an increase in cancer progression risk. Some cell lines studies actually had an inhibition of cell growth, whereas others saw an increase.
How Thyroid Hormone Works Depends on Cell Type, Receptor Type, and Hormone Analogue: Im... - 0 views
Early long-term L-T3 replacement rescues mitochondria and prevents ischemic cardiac rem... - 0 views
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T3 in the post MI individual decreases the MI infarct size and the progression to heart failure. What is really interesting about this study is that the T3 induced mitochondrial biogenesis and activity which is a great thing in recovery of MI and also in disease i.e. cancer. However, it appears to increase HIF-1alpha and angiogenesis which is stimulated by retrograde signaling. There is a muddied picture here. Because T3 stimulates oxidative phosphorylation and mitochondria biogenesis which is favorable for health. However, in this study of rats, it induced HIF-1alpha and angiogenesis in post MI, which is favorable to recovery, yet this is unfavorable for cancer. Yet oxidative phosphorylation is favorable to cancer prevention/elimination and MI recovery.
Thyroid Hormone Receptors and Cancer - 0 views
Increased serum reverse triiodothyronine levels at diagnosis of hepatocellula... - 0 views
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