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Nathan Goodyear

Papillary Thyroid Carcinoma: Differential Diagnosis and Prognostic Values of Its Differ... - 0 views

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    columnar cell variant of papillary cancer associated with increased estrogen and progesterone nuclear receptor expression.  However, when you read this study, the more aggressive tumors were associated with a decrease in progesterone expression.
Nathan Goodyear

Frontiers | Can Reverse T3 Assay Be Employed to Guide T4 vs. T4/T3 Therapy in Hypothyro... - 0 views

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    This study claims no viable benefit for the follow of rT3 in patients on T4/T3 treatment; yet, rT3 increases cancer cell proliferation by up to 80%?!?! Inflammation increases rT3!?!? Context, context, context.
Nathan Goodyear

The Role of Thyroid Hormones in Hepatocyte Proliferation and Liver Cancer - 0 views

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    Oxidative stress/inflammation via HIF-1alpha increase D3 which increases rT3 to increase proliferation in cancer; in contrast, there is a decrease in D1 and D2 to decrease T3 and T4. The question is the systemic versus the TME.
Nathan Goodyear

Nonthyroidal Illness Syndrome and Thyroid Hormone Actions at Integrin αvβ3 | ... - 0 views

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    RT3 favors cancer growth.
Nathan Goodyear

Classical and Non-Classical Thyroid Hormone Intracellular Pathways Involved in T Lympho... - 0 views

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    Both involved. I can only find the abstract to share here.
Nathan Goodyear

Thyroid Hormone Causes Mitogen-Activated Protein Kinase-Dependent Phosphorylation of th... - 0 views

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    Now, here is a kicker...T4 induces ER-alpha activation/signaling similar to estrogen.
Nathan Goodyear

Iodine stimulates estrogen receptor singling and its systemic level is increased in sur... - 0 views

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    Iodine increases ERalpha in secondary to sodium iodide symporter in breast cancer.
Nathan Goodyear

Arquivos Brasileiros de Endocrinologia & Metabologia - Influence of estradiol and triio... - 0 views

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    Study finds T3 effects on ER-alpha is likely a non-genomic pathway.  This study found a down regulation of ER-alpha in tumor cell lines by T3.
Nathan Goodyear

Cancer Cell Gene Expression Modulated from Plasma Membrane Integrin αvβ3 by T... - 0 views

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