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Oral contraceptives shown to reduce Testosterone and DHEA in women, but no effect on cortisol was seen.

Estrogenic Potential of Progestins in Oral Contraceptives to Stimulate Human Breast Cancer Cell Proliferation1

Birth control pills were found to reduce IGF-1 levels in the short term and long term.  Those that had used birth control pills had lower IGF-1 levels compared to those that had never used birth control pills.  This fits with the current knowledge that oral estrogen reduces HGH and IGF-1.  Those were in post-menopausal women, but this is in pre-menopaus women.  This has implications on health, weight, disease...

Salivary testosterone, cortisol, and progesterone: two-week stability, interhormone correlations, and effects of time of day, menstrual cycle, and oral contraceptive use on steroid hormone levels.

Estrogenic potential of progestins in oral contraceptives to stimulate human breast cancer cell proliferation.

The estrogenic activity of synthetic progestins used in oral contraceptives.

The point of this post is not that the author concludes that metformin an statin therapy should be used in PCOS women on birth control with elevated cardiovascular risk; but that with struggling with PCOS should have cardiovascular risk assessment prior to starting birth control.  Again, back to the individualized approach paradigm.

Only abstract available: resistance training in first half of female cycle found to increase muscle mass and strength beyond that of the last 2 weeks.  No difference was found in the use of OCPs.

The 2:16 OH estrone pathway is shown to not be predictive biomarker for breast cancer.

progestins in high dose increase risk of breast cancer

simvastatin, a cholesterol lowering drug, shown to decrease testosterone by 38% in women with PCOS. This supports what has been seen in men on statin therapy.