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Bioactive vitamin D or calcitriol is a steroid hormone that has long been known for its important role in regulating body levels of calcium and phosphorus, and in mineralization of bone. More recently, it has become clear that receptors for vitamin D are present in a wide variety of cells, and that this hormone has biologic effects which extend far beyond control of mineral metabolism. The active form of vitamin D binds to intracellular receptors that then function as transcription factors to modulate gene expression. Like the receptors for other steroid hormones and thyroid hormones, the vitamin D receptor has hormone-binding and DNA-binding domains. The vitamin D receptor forms a complex with another intracellular receptor, the retinoid-X receptor, and that heterodimer is what binds to DNA. In most cases studied, the effect is to activate transcription, but situations are also known in which vitamin D suppresses transcription. Each of the forms of vitamin D is hydrophobic, and is transported in blood bound to carrier proteins. The major carrier is called, appropriately, vitamin D-binding protein. The halflife of 25-hydroxycholecalciferol is several weeks, while that of 1,25-dihydroxycholecalciferol is only a few hours. The vitamin D receptor binds several forms of cholecalciferol. Its affinity for 1,25-dihydroxycholecalciferol is roughly 1000 times that for 25-hydroxycholecalciferol, which explains their relative biological potencies

You don't have to lie awake for hours past your bedtime to have insomnia. The condition manifests itself in several ways: trouble falling asleep (known as sleep-onset insomnia), staying asleep (sleep-maintaining insomnia), or waking up too early (early morning awakening

"The major factor which stimulates weight gain in winter months is vitamin D. Human bodies get vitamin D from sunlight; as the hours of sunlight become less with the onset of fall, so our levels of vitamin D decrease. Low levels of vitamin D affect the brain's production of the hormone leptin. Leptin plays a vital role in controlling appetite and metabolism; so as the amount of vitamin D in our bodies decreases so does the leptin, and this causes an increase in our appetite and a change in our metabolism. Researchers at Aberdeen University found that obese people had 10% less vitamin D than people of average weight. The study also found that excess body fat absorbed vitamin D so the body couldn't use it. Scientists now believe that there is a direct correlation between obesity and low levels of vitamin D.

Seasonality of UV-radiation and vitamin D status at 69 degrees north. Brustad M, Edvardsen K, Wilsgaard T, Engelsen O, Aksnes L, Lund E. Photochem Photobiol Sci. 2007 Aug;6(8):903-8. Epub 2007 Jun 27. PMID: 17668121 The generally high dietary intakes of vitamin D, especially in winter, mask largely the effect of seasonal variation in UV-exposure, causing an atypical seasonal variation in vitamin D status. The UV-hour variable significantly predicted 25(OH)D levels in blood when adjusted for intakes and artificial UV-radiation exposure and sun holidays abroad.

Ginkgo has many alleged nootropic properties, and is mainly used as memory[25] and concentration enhancer, and anti-vertigo agent. However, studies differ about its efficacy. The largest and longest independent clinical trial to assess ginkgo biloba's ability to prevent memory loss has found that the supplement does not prevent or delay dementia or Alzheimer's disease.[26] Some controversy has arisen over the conclusions drawn by some studies that were allegedly funded by a firm which marketed Ginkgo.[27] In 2002, a long-anticipated paper appeared in JAMA (Journal of the American Medical Association) titled "Ginkgo for memory enhancement: a randomized controlled trial." This Williams College study, sponsored by the National Institute on Aging rather than Schwabe, examined the effects of ginkgo consumption on healthy volunteers older than 60. The conclusion, now cited in the National Institutes of Health's ginkgo fact sheet, said: "When taken following the manufacturer's instructions, ginkgo provides no measurable benefit in memory or related cognitive function to adults with healthy cognitive function." ... The impact of this seemingly damning assessment, however, was ameliorated by the almost simultaneous publication of a Schwabe-sponsored study in the less prestigious Human Psychopharmacology. This rival study, conducted at Jerry Falwell's Liberty University, was rejected by JAMA, and came to a very different-if not exactly sweeping-conclusion: There was ample evidence to support "the potential efficacy of Ginkgo biloba EGb 761 in enhancing certain neuropsychological/memory processes of cognitively intact older adults, 60 years of age and over." According to some studies, in a few cases, Ginkgo can significantly improve attention in healthy individuals.[28][29] Allegedly, the effect is almost immediate and reaches its peak in 2.5 hours after the intake.[30] [edit] In dementia A 2004 conference paper[31] summarizes how various trials indicate that Gi

"THURSDAY, Dec. 17 (HealthDay News) -- In a surprise finding, Canadian researchers report that the immediate effect of the fish oil fatty acids that are good for the heart is a short-term increase in blood fats and the molecules that help them form clots. "We were surprised to find that the acute response has some potentially negative effects in comparison to what you might expect from chronic, long-term intake," said Lindsay E. Robinson, an associate professor of nutrition at the University of Guelph, and leader of the group reporting the finding in the January issue of the Journal of Nutrition. However, the study results shouldn't affect the current recommendation for eating more oily fish to get the omega-3 polyunsaturated acids that reduce the risk of blood clots that can cause heart attacks and stroke, Robinson said. "The recommendation to increase intake is very well-studied, and this doesn't change it," she said. And the effects were seen in a selected group of middle-aged men with metabolic syndrome, a combination of high blood pressure, obesity and elevated blood fat levels, Robinson noted. In the study, eight men had controlled intake of three regimens: high doses of omega-3 fatty acids, low doses of them and just plain water. Robinson and her colleagues measured several blood components involved in clotting, including fats and clotting factors such as plasminogen-activator inhibitor-1 (PAI-1) for the following eight hours. PAI-1 inhibits the destruction of blood clots, so high levels of it in the blood increase the risk of artery-blocking clots. The researchers found that both omega-3 fatty acid regimens increased blood fat and clotting factor activity. But the increase in clotting factor was greater for the higher doses of omega-3 fatty acids than for the lower intakes. Robinson said her group hopes to do further studies of the immediate effects of omega-3 fatty acid intake. "We need to look at the mechanisms, why blood lipid levels go up," she

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. Stanhope KL, Schwarz JM, Keim NL, Griffen SC, Bremer AA, Graham JL, Hatcher B, Cox CL, Dyachenko A, Zhang W, McGahan JP, Seibert A, Krauss RM, Chiu S, Schaefer EJ, Ai M, Otokozawa S, Nakajima K, Nakano T, Beysen C, Hellerstein MK, Berglund L, Havel PJ. J Clin Invest. 2009 May;119(5):1322-34. Epub 2009 Apr 20. PMID: 19381015 doi: 10.1172/JCI37385. Studies in animals have documented that, compared with glucose, dietary fructose induces dyslipidemia and insulin resistance. To assess the relative effects of these dietary sugars during sustained consumption in humans, overweight and obese subjects consumed glucose- or fructose-sweetened beverages providing 25% of energy requirements for 10 weeks. Although both groups exhibited similar weight gain during the intervention, visceral adipose volume was significantly increased only in subjects consuming fructose. Fasting plasma triglyceride concentrations increased by approximately 10% during 10 weeks of glucose consumption but not after fructose consumption. In contrast, hepatic de novo lipogenesis (DNL) and the 23-hour postprandial triglyceride AUC were increased specifically during fructose consumption. Similarly, markers of altered lipid metabolism and lipoprotein remodeling, including fasting apoB, LDL, small dense LDL, oxidized LDL, and postprandial concentrations of remnant-like particle-triglyceride and -cholesterol significantly increased during fructose but not glucose consumption. In addition, fasting plasma glucose and insulin levels increased and insulin sensitivity decreased in subjects consuming fructose but not in those consuming glucose. These data suggest that dietary fructose specifically increases DNL, promotes dyslipidemia, decreases insulin sensitivity, and increases visceral adiposity in overweight/obese adults.

Although there is a large body of evidence showing that foods low in sodium can protect our arteries and prevent a heart attack, this new study is different in that it shows that salty foods can harm our arteries in 30 minutes to 2 hours, something it might have never occured to us it could happen.

"It's well known that African Americans have low levels of vitamin D in their blood. In fact, this seems to be generally true for humans of tropical origin. In a study from Hawaii, vitamin D status was assessed in healthy, visibly tanned young adults who averaged 22.4 hours per week of unprotected sun exposure. Yet 51% had levels below the current recommended minimum of 75 nmol/L (Binkley et al., 2007). In a study from south India, levels below 50 nmol/L were found in 44% of the men and 70% of the women. The subjects are described as "agricultural workers starting their day at 0800 and working outdoors until 1700 with their face, chest, back, legs, arms, and forearms exposed to sunlight" (Harinarayan et al., 2007). In a study from Saudi Arabia, levels below 25 nmol/L were found in respectively 35%, 45%, 53%, and 50% of normal male university students of Saudi, Jordanian, Egyptian, and other origins (Sedrani, 1984)."

"This is not one of our usual hour-long live discussions. Rather, this is an online question-and-answer session. Your questions and Dr. Vieth's answers will appear at the bottom of this page after 1 p.m. EDT today."

This classic rhubarb crumble recipe will take you to comfort food heaven in six short steps and under an hour. Less than 30 mins preparation time 30 mins to 1 hour cooking time Source: James Martin from Housecall

Children spend long hours in front of the box - so what? If you watch TV for 3 hours per day, by the time you reach the age of 70 you will have spent almost 9 years watching TV. Many children spend more time watching TV than they spend in school.

Tristar Beverages
Mango Dash
Offer three varieties of Dash Mango Juice bottles. These bottles are manufactured from all food grade plastics. Our range of Dash Mango Juice bottles are known for their quality and look. We are Supplier & Manufacturer of Dash Mango Juice in Madhya Pradesh, Uttar Pradesh, Bombay, Rajasthan, Chhattisgarh, Maharashtra and Gujarat.

PEPSI India
Slice Brand History
Slice was launched in India in 1993 as a refreshing mango drink and quickly went on to become a leading player in the category.
In 2008, Slice was relaunched with a winning product formulation that made consumers fall in love with its taste. With new pack graphics and clutter-breaking advertising, Slice has built a powerful appeal.
Slice Nutritional Facts & Ingredient Details

COCA Cola
MAAZA THE WHOLESOME FAMILY FUN
Introduced in 1970s, Maaza has today come to symbolize the very spirit of mangoes. Universally loved for its taste, color, thickness and wholesome properties, Maaza is the mango lover's first choice.

Dabar
Mango Nectar is prepared from the best quality mangoes to ensure consistent quality around the year. Packed with natural goodness of mango, Mango Nectar has all the ingredients to make you smile.
Some of you may find it hard to believe, but mango nectar gives you all the energy you need to keep you going for hours together. As a matter of fact, Mango Nectar is very popular amongst the children, as it is extremely juicy and has a pleasant flavour.
It is an excellent source of Vitamin C and is naturally high in Betacarotene.

Fresco MANGO JUICE
Mango Juice is perhaps one of the tastiest fruit drinks which is loved by all age group. Fresco mango juices are made from fresh Mangoes. The mango juice is rich in nutrients, Vitamin A, B, C, Iron, Phosphorus Calcium and Potassium. 200 ml, 300 ml, 600 ml and 1 litre bottles are av

Brand History The company was founded in the year 1977 by first generation entrepreneur Mr. Kanti Parasrampuria. He has a vast work experience in the field of textiles, beverages and plastics and a profound business acumen and managerial alacrity. The company benefits from his expertise and guidance and also relies on a highly experienced and well qualified professional management team for its day to day operations. Brand Advantage The company owns a fully automatic plant to manufacture 6000 liters per hour of fruit based beverages at Mandideep near Bhopal (M.P.), India. It is a state-of-art plant with two PET blowing and filling lines, one V-Pak (aseptic juice carton) and one stand-up pouch filling line. The infrastructure is par-excellence and ensures that delicious, safe and hygienic products are delivered to the market. The beverages made by us are untouched by hand are produced under stringent conditions. The beverage division has achieved the prestigious ISO 22000:2005 including HACCP certification from the Swiss multinational certification agency SGS. The facility is also certified ISO 9001:2008 from ICS. All the equipment's used in the plant are installed by vendors that are approved by big multinational beverage companies. The raw and packaging material procured is from good quality sources which are first audited for quality. The plant is centrally located in Bhopal with very good road, air and rail link to rest of the country. Our products are currently available in 15 states of India (updated Feb 2013) and counting. Mango dash created a great deal of excitement in its category and celebrated the indulgence in mangoes like no other brand had done before. While other players have portrayed the mango as a simple and innocent fruit, Mango dash celebrates the sheer indulgence and sensuality involved in consuming a mango. The creative 'Aamsutra' idea communicates the experience of extreme sensuous pleasure through the act of drinking M

Fruit Juice Companies and Brands In India

PEPSI India
Slice
Slice was launched in India in 1993 as a refreshing mango drink and quickly went on to become a leading player in the category.

In 2008, Slice was relaunched with a winning product formulation that made consumers fall in love with its taste. With new pack graphics and clutter-breaking advertising, Slice has built a powerful appeal.

COCA Cola
Maaza
Introduced in 1970s, Maaza has today come to symbolize the very spirit of mangoes. Universally loved for its taste, color, thickness and wholesome properties, Maaza is the mango lover's first choice.The Union Beverages Factory, based in the UAE, began selling Maaza as a franchisee in the Middle East and Africa in 1976. By 1995, it had acquired rights to the Maaza brand in these countries through Maaza International Co LLC Dubai. Maaza was launched in 1976 in India. and in India, Maaza was acquired by Coca-Cola India in 1993 from Parle-Bisleri along with other brands

Dabur India
Dabur India Limited is a leading Indian consumer goods company with interests in Hair Care, Oral Care, Health Care, Skin Care, Home Care and Foods. From its humble beginnings in the bylanes of Calcutta way back in 1884 as an Ayurvedic medicines company, Dabur India Ltd has come a long way today to become a leading consumer products manufacturer in India.
Basics of Nutrition & Healthy Living
Eating the right food along with daily exercise will keep the body healthy and fit. A fit and healthy body ensures prevention from ailments. While all forms of exercise will benefit, a combination of strength, endurance, balance & stretching exercises are best. Limit inactive behavior such as television watching and computer time.

Tristar Beverages
Mango Dash
The company was founded in the year 1977 by first generation entrepreneur Mr. Kanti Parasrampuria. He has a va

We offer the full range of blood test at home with results available as early as 48 hours. Mobile Phlebotomy offered for blood sample collection.

a handful of fresh spinachseveral strawberries⅓ ripe avocado4-5 raw macadamia nuts1½ tsp raw apple cider vinegar1 tsp raw agave nectarpinch of sea saltground black pepper to taste Clean and stem spinach; tear into bite-size pieces and throw in a bowl. Slice strawberries, cube avocado, and coarsely chop macadamia nuts. Add. Though macadamia nuts are ideal, Brazil nuts or cashews may be used as a substitute-because really, who besides me has raw macadamia nuts on hand.Drizzle salad mixture with vinegar and agave, add a pinch of salt (to bring out the sweetness) and toss.Dish onto a plate and garnish with fresh ground black pepper. Serve within an hour of preparing as the spinach will wilt.Serves 1 starter salad. Double the recipe for an entree, or multiply the above quantities by the number of guests. Enjoy!

Urinoct Only $49/Bottle Limited Time Offer! Urinoct Special Deal + Special 51% Discount Save $300 + 60 Days Money Back Guarantee Urinoct urinoct FDA Five Star Urinoct The #1 Solution To Maintain a Prostate and boost your manhood's performance. Prostate health supplements are specifically formulated to support men in maintaining optimal levels of prostate function. These supplements are created with natural ingredients in order to furnish fundamental nutrients for maintaining prostate well-being. Regular Price: $99/per bottle Only for: $49/per bottle Buy Now What Is Urinoct? Urinoct is a nutritional supplement featuring natural ingredients that support prostate health. Developed by a surgeon named Dr. Wesley, Urinoct claims to shrink your prostate, raise testosterone, increase sperm production, boost fertility, enhance lean muscle mass, and reverse balding, among other benefits. The prostate gland is an important part of the male reproductive system, and it plays a crucial role in the production of semen. However, as men age, their risk of developing prostate-related health problems, such as prostate cancer, increases. This is where Urinoct comes in. With Urinoct, you can expect to experience reduced inflammation and increased ability for bladder emptying. Plus, your confidence will get a boost. Every ingredient in Urinoct is sourced from the purest and most potent sources, and the ratios are carefully balanced. Furthermore, each element of the formula is backed by scientific data, ensuring positive results without any risk of side effects. Urinoct is a groundbreaking supplement specifically formulated to address the root causes of Benign Prostatic Hyperplasia (BPH) and urinary issues in men. With its unique combination of natural ingredients, Urinoct not only alleviates the symptoms associated with an enlarged prostate but also promotes overall prostate and urinary health. The creation of the Urinoct supplement undergoes strict manufacturing s

Ikaria Lean Belly Juice Only $69/Bottle Limited Time Offer! Special Deal + Special 80% Discount Save $840+ 180 Days Money Back Guarantee lkaria Lean Belly Juice lkaria Lean Belly Juice Five Star Ikaria Lean Belly Juice is a powerful new formula that makes weight loss easier, faster and much more fun… Ikaria Lean Belly Juice is a powerful weight management complex that is 100% herbal and pure, which can aid in burning stubborn belly fat effectively and helps you lose weight naturally. Regular Price: $179/per bottle Only for: $69/per bottle Buy Now What Is Ikaria Lean Belly Juice? Ikaria Lean Belly Juice formula is different from other weight loss or diet pills. You might have never tried or seen something like or even close. Ikaria Lean Belly Juice for losing belly fat before. As the name suggests, this Ikaria belly fat-burning juice is based on a daily ritual of the healthiest part of the world, Ikaria. Researchers found that a number of natural ingredients, fruits, and plant extracts available on the island can help lose weight by eliminating toxic lipid molecules and reducing high uric acid levels in the human body. Ikaria Lean Belly Juice is an effective weight loss diet supplement that is made up of several effective, scientifically-proven ingredients that can help you lose weight. It aids in shedding belly fat and excess weight. This product has incredible health benefits to clients. The Ikaria Lean Belly Juice formula was created by a group of experts who wanted to help all those people who were struggling to lose weight. The formula of the supplement has been prepared under strict conditions in an FDA-registered facility, and its blend of natural ingredients like milk thistle supports weight loss incredibly. Each bottle comes with 30 days of servings that can be blended together with liquids. The powder's formula is produced in GMP-certified, FDA-approved labs to guarantee high-quality and safety. A lot of people have questions rega