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Luteolin is a flavonoid and more specifically a flavone. It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an agent in the prevention of inflammation, a promoter of carbohydrate metabolism, and an immun

Luteolin is a naturally occurring compound found in foods including parsley, artichoke leaves, celery, peppers, olive oil, rosemary, lemons, peppermint, sage, thyme, and many others. Luteolin has antioxidant, anti-inflammatory, anti-allergic, anticancer,

In healthy people who have been exposed to tuberculosis, a single oral dose of vitamin D enhances their immunity against this bacterial infection.

Martineau AR, Wilkinson RJ, Wilkinson KA, Newton SM, Kampmann B, Hall BM, Packe GE, Davidson RN, Eldridge SM, Maunsell ZJ, Rainbow SJ, Berry JL, Griffiths CJ. A single dose of vitamin D enhances immunity to mycobacteria. Am J Respir Crit Care Med. 2007

Liu PT, Stenger S, Tang DH, Modlin RL. Cutting Edge: Vitamin D-Mediated Human Antimicrobial Activity against Mycobacterium tuberculosis Is Dependent on the Induction of Cathelicidin. J Immunol. 2007 Aug 15;179(4):2060-3. PMID: 17675463 [PubMed - in pr

Bikle DD. What is new in vitamin D: 2006-2007. Curr Opin Rheumatol. 2007 Jul;19(4):383-8. PMID: 17551371 [PubMed - in process]

According to Dole Nutrition Institute (run by Dole Food Company Inc., one of the largest sellers of organic fruits and vegetables) mangoes are one of the 33 healthiest foods on the planet. Mangoes, the King of fruit, are known to support immunity, lower bad cholesterol and regulate homocysteine to protect the arteries. One of the best sources of beta carotene, quercetin and astragalin, mangoes provide powerful antioxidants that help preserve the body's antioxidant enzymes and prevent free radical damage

Floyd Chilton and colleagues wanted to examine whether theses fatty acids might have other effects, and developed a dietary intervention strategy in which 27 healthy humans were fed a controlled diet mimicking the w6/w3 ratios of early humans over 5 weeks. They then looked at the gene levels of immune signals and cytokines (protein immune messengers), that impact autoimmunity and allergy in blood cells and found that many key signaling genes that promote inflammation were markedly reduced compared to a normal diet, including a signaling gene for a protein called PI3K, a critical early step in autoimmune and allergic inflammation responses. This study demonstrates, for the first time in humans, that large changes in gene expression are likely an important mechanism by which these omega fatty acids exert their potent clinical effects

Perioperative immunonutrition in head and neck cancer. Sorensen LD, McCarthy M, Baumgartner MB, Demars CS. Laryngoscope. 2009 May 20. [Epub ahead of print] PMID: 19459146 DOI: 10.1002/lary.20494

Immunological parameters: what do they mean? Calder PC. J Nutr. 2007 Mar;137(3 Suppl 2):773S-80S. Review. PMID: 17311974

K. L. Fritsche Are Omega-3 Fatty Acids Effective in Enhancing Tumoricidal Cell Activity? J. Nutr., December 1, 2005; 135(12): 2916S - 2917S.

Valio Gefilus® MAX has been shown in tests to calm a stressed stomach. Valio Gefilus® MAX products contain a combination of four functional bacterial strains or probiotics. The core of the probiotic combination is Lactobacillus rhamnosus GG (LGG®, ATCC 53103), familiar from other Valio Gefilus® products. LGG® is the most researched probiotic strain in the world and is known particularly for its effect in strengthening immunity. It has been suggested that a combination of several probiotic strains alleviates the symptoms of stressed stomach more efficiently. In addition to LGG®, Gefilus® MAX products contain three other functional bacterial strains (L. rhamnosus Lc705, Propionibacterium freudenreichii ssp. shermanii JS, Bifidobactetrium animalis subsp. lactis Bb-12®). Together these four probiotic strains form a unique combination that strengthens immunity and calms a stressed stomach.

These results suggest that combination chemotherapy (FO+Cur or Lim) may favorably modulate CD4+ T-cell-mediated inflammation.D ietary curcumin and limonin suppress CD4+ T-cell proliferation and interleukin-2 production in mice. Kim W, Fan YY, Smith R, Patil B, Jayaprakasha GK, McMurray DN, Chapkin RS. J Nutr. 2009 May;139(5):1042-8. Epub 2009 Mar 25. PMID: 19321585 doi:10.3945/jn.108.102772

Evolution and function of vitamin D. Holick MF. Recent Results Cancer Res. 2003;164:3-28. Review. PMID: 12899511

Conclusion We demonstrated that the VDRE in the CAMP gene originated from the exaptation of an AluSx SINE in the lineage leading to humans, apes, OWMs and NWMs and remained under purifying selection for the last 55-60 million years. We present convincing evidence of an evolutionarily fixed, Alu-mediated divergence in steroid hormone nuclear receptor gene regulation between humans/primates and other mammals. Evolutionary selection to place the primate CAMP gene under regulation of the vitamin D pathway potentiates the innate immune response and may counter the anti-inflammatory properties of vitamin D. Exaptation of an ancient Alu short interspersed element provides a highly conserved vitamin D-mediated innate immune response in humans and primates. Gombart AF, Saito T, Koeffler HP. BMC Genomics. 2009 Jul 16;10:321. PMID: 19607716 doi:10.1186/1471-2164-10-321

Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe? Nunn AV, Bell JD, Guy GW. Nutr Metab (Lond). 2009 Apr 16;6:16. PMID: 19371409 doi:10.1186/1743-7075-6-16

Overview of general physiologic features and functions of vitamin D. DeLuca HF. Am J Clin Nutr. 2004 Dec;80(6 Suppl):1689S-96S. Review. PMID: 15585789