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Matti Narkia

Single food focus dietary guidance: lessons learned from an economic analysis of egg co... - 0 views

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    Single food focus dietary guidance: lessons learned from an economic analysis of egg consumption.
    Schmier JK, Barraj LM, Tran NL.
    Cost Eff Resour Alloc. 2009 Apr 14;7:7.
    PMID: 19366457

    Methods
    A risk apportionment model estimated the increased risk for coronary heart disease (CHD) attributable to egg cholesterol content, the decreased risk for other conditions (age-related macular degeneration (AMD), cataract, neural tube defects, and sarcopenia) associated with egg consumption, and a literature search identified the cost of illness of each condition. The base 795 case scenario calculated the costs or savings of each condition attributable to egg cholesterol or nutrient content.

    Results
    Given the costs associated with CHD and the benefits associated with the other conditions, the most likely scenario associated with eating an egg a day is savings of $2.82 billion annually with uncertainty ranging from a net cost of $756 million to net savings up to $8.50 billion.

    Conclusion
    This study evaluating the economic impact of egg consumption suggests that public health campaigns promoting limiting egg consumption as a means to reduce CHD risk would not be cost-effective from a societal perspective when other benefits are considered. Public health intervention that focuses on a single dietary constituent, and foods that are high in that constituent, may lead to unintended consequences of removing other beneficial constituents and the net effect may not be in its totality a desirable public health outcome. As newer data become available, the model should be updated.
Matti Narkia

Twice single doses of 100,000 IU of vitamin D in winter is adequate and safe ... - 1 views

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    Twice single doses of 100,000 IU of vitamin D in winter is adequate and safe for prevention of vitamin D deficiency in healthy children from Ushuaia, Tierra Del Fuego, Argentina.
    Tau C, Ciriani V, Scaiola E, Acuña M.
    J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):651-4. Epub 2007 Jan 25.
    PMID: 17257830
    doi:10.1016/j.jsbmb.2006.12.027

    These results disclosed that to prevent vitamin D deficiency for children at zones of risk at the south of our country, double supplementation of 100,000 IU of vitamin D during autumn and winter, would be adequate and safe.
Matti Narkia

Pharmacokinetics of a single, large dose of cholecalciferol -- Ilahi et al. 87 (3): 688... - 0 views

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    Pharmacokinetics of a single, large dose of cholecalciferol.
    Ilahi M, Armas LA, Heaney RP.
    Am J Clin Nutr. 2008 Mar;87(3):688-91.
    PMID: 1832660

    Conclusions: Cholecalciferol (100 000 IU) is a safe, effective, and simple way to increase calcidiol concentrations. The dosing interval should be ≤2 mo to ensure continuous serum calcidiol concentrations above baseline.

    Our study highlights that 100 000 IU cholecalciferol is a safe, efficient, and cost-effective means to increase calcidiol concentrations in the elderly. From this study we can safely recommend 100 000 IU cholecalciferol dosed every 2 mo in persons with moderate baseline calcidiol concentrations. However, in those persons with baseline calcidiol concentrations < 20 ng/mL, even this large dose will not adequately raise their calcidiol concentrations.
Matti Narkia

One dose of vitamin D boosts TB immunity - New Zealand's source for health news on Stuf... - 0 views

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    In healthy people who have been exposed to tuberculosis, a single oral dose of vitamin D enhances their immunity against this bacterial infection.
Matti Narkia

A Single Dose of Vitamin D Enhances Immunity to Mycobacteria -- Martineau et al. 176 (2... - 0 views

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    Martineau AR, Wilkinson RJ, Wilkinson KA, Newton SM, Kampmann B, Hall BM, Packe GE, Davidson RN, Eldridge SM, Maunsell ZJ, Rainbow SJ, Berry JL, Griffiths CJ.
    A single dose of vitamin D enhances immunity to mycobacteria.
    Am J Respir Crit Care Med. 2007
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