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Tofu and cognitive function: food for thought. Grodstein F, Mayeux R, Stampfer MJ. J Am Coll Nutr. 2000 Apr;19(2):207-9. Review. PMID: 10763901 In addition, a plausible biologic hypothesis is generally an important part of judging epidemiologic relations. While high tofu intake may lead to lower plasma estrogen levels [12], we do not know how tofu influences estrogen levels in the brain; we also know very little about estrogen effects in men. Furthermore, data have not even consistently indicated that low endogenous estrogen levels are directly related to cognitive function in non-demented subjects [13]. The authors also posit a non-estrogen mediated hypothesis for the effects of tofu, namely that soy inhibits hippocampal tyrosine kinase and may block long-term potentiation (the likely mechanism by which humans learn and remember). Still, considerably more work must be done to substantiate this hypothesis. Finally, the single measures of outcome used in this study may have limited value, as cognitive function and brain structure change over time. Factors which predict these measures at one point may or may not be the same as those which predict decline over time; fundamentally, the public health interest is in preventing cognitive decline, as the steepness of the decline trajectory likely provides an early marker for risk of the more clinically relevant result-dementia.

"The common culprit is soy, a plant that contains chemicals with estrogen-like and anti-estrogenic properties - making it a nutritional minefield for breast cancer survivors. While Western diets are relatively low in soy - compared with the typical diet in Asia, where people eat soy daily - the percentage of Americans consuming soy at least once a week has increased from 15% in 1997 to 28% in 2003. In the meantime, studies on the effect of soy on breast cancer recurrence and mortality have been conflicting, with some showing that it can reduce risk, while others show an elevated rate of recurrent disease among high soy consumers. Now the largest study to date of soy's effect on breast cancer suggests that eating soy, even in large amounts, may not be harmful after all, and may even reduce recurrence and death from the disease. But while the findings are intriguing, not all doctors are ready to tout the benefits of tofu

"Wednesday, December 9, 2009 By Amy Norton NEW YORK (Reuters Health) - Supplements containing soy isoflavones may do little to preserve women's bone mass after menopause. In a study of more than 200 women ages 46 to 65, researchers found that the soy supplement did not appear to ward off bone-density loss over 3 years. In general, women on the supplement showed the same degree of bone loss as those given a placebo -- though there was some evidence that a higher dose helped protect bone density in the hip. The findings, reported in the American Journal of Clinical Nutrition, add to a conflicting body of research on soy and postmenopausal bone health. Some studies have suggested that soy-based foods, isolated soy protein or isoflavone-containing supplements may be beneficial, while others have found no advantage. Isoflavones are natural chemicals found in soybeans and certain other plant foods that are structurally similar to estrogen, and may have certain estrogen-like effects in the human body. Since declining estrogen levels after menopause spur bone-density loss, isoflavone supplements could theoretically protect women's bone mass. The current findings, however, do not support that theory."

"Researchers at Johns Hopkins are reporting what is believed to be the first conclusive evidence in men that the long-term ill effects of vitamin D deficiency are amplified by lower levels of the key sex hormone estrogen, but not testosterone. In a national study in 1010 men, to be presented Nov. 15 at the American Heart Association's (AHA) annual Scientific Sessions in Orlando, researchers say the new findings build on previous studies showing that deficiencies in vitamin D and low levels of estrogen, found naturally in differing amounts in men and women, were independent risk factors for hardened and narrowed arteries and weakened bones. Vitamin D is an essential part to keeping the body healthy, and can be obtained from fortified foods, such as milk and cereals, and by exposure to sunlight.

"(NaturalNews) Regularly eating high levels of tofu may increase the risk of the memory loss associated with dementia, according to a new study conducted by researchers from Loughborough University in the United Kingdom, and published in the journal Dementias and Geriatric Cognitive Disorders. Prior research has found that women over the age of 65 who receive hormone therapy may double their risk of dementia. This may occur because estrogen promotes cell growth, which may actually do damage to the aging brain, Hogervorst said. Alternately, high levels of estrogen might enhance the cell-damaging effects of free radicals. Hogervorst also noted that much of tofu consumed by study participants might have been preserved with formaldehyde, a common practice in Indonesia. Formaldehyde has been strongly linked to various forms of cell damage, and might be responsible for the memory effects observed. Prior research has found that older Japanese-American men who consumed high levels of tofu are also at an elevated risk for dementia, however. Researchers investigated the connection between memory loss and diet for 719 elderly urban and rural residents of Java, Indonesia. The found that those who ate tofu at least once per day performed significantly worse on memory tests than those who ate tofu less frequently. The effect was particularly strong among those over the age of 68."

Soy Food Intake and Breast Cancer Survival. Xiao Ou Shu et al. JAMA Vol. 302 No. 22, December 9, 2009; 302(22):2437-2443. Results During the median follow-up of 3.9 years (range, 0.5-6.2 years), 444 deaths and 534 recurrences or breast cancer-related deaths were documented in 5033 surgically treated breast cancer patients. Soy food intake, as measured by either soy protein or soy isoflavone intake, was inversely associated with mortality and recurrence. The hazard ratio associated with the highest quartile of soy protein intake was 0.71 (95% confidence interval [CI], 0.54-0.92) for total mortality and 0.68 (95% CI, 0.54-0.87) for recurrence compared with the lowest quartile of intake. The multivariate-adjusted 4-year mortality rates were 10.3% and 7.4%, and the 4-year recurrence rates were 11.2% and 8.0%, respectively, for women in the lowest and highest quartiles of soy protein intake. The inverse association was evident among women with either estrogen receptor-positive or -negative breast cancer and was present in both users and nonusers of tamoxifen. Conclusion Among women with breast cancer, soy food consumption was significantly associated with decreased risk of death and recurrence.

The study of 50,000 women states that eating Grapefruit can increase the risk of breast cancer. The fruit is believed to boost blood levels of estrogen, the hormone associated with increased risk of the illness

"Study Shows Vitamin D Supplements May Be Useful in Preventing Heart Disease Nov. 16, 2009 (Orlando, Fla.) -- Some men with low levels of vitamin D in their blood are at particularly high risk of developing heart disease and weakened bones that can lead to osteoporosis, researchers report. In a study of more than 1,000 men, those with low levels of both vitamin D and the sex hormone estrogen were at significantly increased risk of having cardiovascular disease, says study head Erin Michos, MD, a cardiologist at Johns Hopkins. "They were also at dramatically increased risk of osteopenia," or bone loss that can lead to osteoporosis, she says. "Our results suggest that vitamin D supplements, which are already prescribed to treat osteoporosis, may also be useful in preventing heart disease," Michos tells WebMD. Men with low levels of vitamin D and testosterone, on the other hand, were not at heightened risk for heart disease or osteopenia."

(NaturalNews) Zinc is an integral part of the male hormonal system, and a primary part of the semen. It plays a major role in the production of sperm. Studies also reveal that Zinc Deficiency may be a cause of Prostate Enlargement.\n\nAs men age into their 50s and older, there is a natural decline in zinc. A zinc deficiency can lead to prostate enlargement, as well as a number of other male problems including impotency. This is because the prostate tissues are highly dependent on zinc to maintain its health and integrity. Zinc increases sperm count and sperm motility. High zinc levels also mean lower levels of estrogen and prolactin thereby reducing the risk of prostate disease.

An ecologic study of dietary and solar ultraviolet-B links to breast carcinoma mortality rates. Grant WB. Cancer. 2002 Jan 1;94(1):272-81. PMID: 11815987 CONCLUSIONS It is hypothesized that animal products are associated with risk for breast carcinoma because they are associated with greater amounts of insulin-like growth factor-1and lifetime doses of estrogen. Vegetable products contain several risk reduction components including antioxidants and phytoestrogens. The association with latitude is very likely because of solar UV-B radiation and vitamin D. Alcohol modulates estrogen's effects on breasts. Fish intake is associated with risk reduction through vitamin D and n-3 oils. These results are consistent with those of many case-control and cohort studies but should be assessed in well designed cohort studies.

Many postmenopausal women are looking for alternatives to hormone therapy, especially in light of research findings in 2003 from the Women's Health Initiative. With major funding from the National Institutes of Health, this initiative studied the risks of combined estrogen and progestin therapy, among other health issues of critical importance to postmenopausal women. Of particular interest are phytoestrogens, which have been gaining popularity because they are marketed as "natural," because of the alleged health benefits they provide, and because they are available in a wide range of foods and supplements. This fact sheet provides an overview of phytoestrogens and discusses their potential role in osteoporosis prevention and treatment.

It was observed that in post-menopausal women with documented heart disease from the Estrogen Replacement and Atherosclerosis (ERA) trial, a multicenter clinical trial evaluating the effects of hormone replacement therapy on atherosclerotic progression, in the group consuming the highest-saturated dietary fat diet (12.0% Sat Fat), an enlargement in coronary diameter of 0.01 mm and a 0.1% regression in coronary artery stenosis

European experts in cancer and nutrition are meeting in Zurich, Switzerland late this month to discuss cutting-edge research in one of the most important and fiercely debated topics in cancer prevention: the link between diet and cancer. There is growing evidence that many cancers may be prevented through healthy lifestyle, including a nutritionally balanced diet. In addition, nutritional problems can also have a negative impact on cancer management and the lives of patients. Other presentations will include new data on topics such as: Childhood nutrition and later breast cancer risk The anti-tumour effects of green tea Malnutrition and patient distress in cancer Possible anti-tumour effects of soy extracts in mice Estrogens in beef and cancer risk

"In recent years, melatonin has been heralded as everything from snake-oil to miracle cure-all. As is often the case, the truth seems to lie somewhere in between. But make no mistake about it, melatonin is not a vitamin or supplement; despite it's over-the-counter accessibility, it is a hormone in the same category as estrogen, testosterone and thyroid hormone. Hormones, as a whole, are some of the most powerful regulatory chemicals functioning within the body. Therefore, hormone-containing supplements and medications should always be used judiciously, never indiscriminately or haphazardly. "

High tofu intake is associated with worse memory in elderly Indonesian men and women. Hogervorst E, Sadjimim T, Yesufu A, Kreager P, Rahardjo TB. Dement Geriatr Cogn Disord. 2008;26(1):50-7. Epub 2008 Jun 27. PMID: 18583909 DOI: 10.1159/000141484 CONCLUSION: The results for tofu consumption as a risk factor for low memory function may tie in with the Honolulu Asia Aging Study data. It is unclear whether these negative associations could be attributed to potential toxins or to its phytoestrogen levels. Estrogen (through which receptors phytoestrogens can exert effects) was found to increase dementia risk in women over 65 years of age. Tempe contains high levels of phytoestrogens, but (due to fermentation) also exhibits high folate levels which may exert protective effects. Future studies should validate these findings and investigate potential mechanisms.

Susu kedelai sangat kaya akan gizi dan protein. Susu kedelai mengandung isoflavon (zat alami yang dapat bertindak sebagai estrogen dalam tubuh dan memiliki fungsi sebagai pelindung).

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Appearance body shape is a very important thing , especially for women . Especially when it comes to body shape , all vying for the diet . Moreover not a few women terobesi has large breasts make it look sexy . Not a few of them in the end be tempted to do the plastic surgery to enlarge and beautify the breasts . But beyond the instant way to perform plastic surgery , not a few women who choose natural ways to increase breast size . How do I ? Here are his tips Knoworthy quoted as follows : Fish Oil A blogger from the site Natural Breast Enhancement ( NBE ) , Emily Loretta , said Norwergian Cod Liver Oil ( NCLO ) can be used to enlarge breasts . He always put the oil after a shower . But that should be known , the fish oil smell was overpowering . It means you should be able to withstand the fishy aroma . However , the smell will go away after a bath . Recognized Emily , her breasts rising up to several inches . massage This is one of the natural breast enlargement methods . The traditional therapists call this breast massage as part of the Ayurveda massage . In Canada for example , plural breast massage done . It is also grown in Asia , where the beauty salon has been using breast massage for breast growth . To be known , this massage can be done only with the written consent . onions Garlic is also known to enlarge the breasts . A mixture of fresh garlic , honey , and turmeric ( powder ) applied to the breast . This trick is useful for tightening and prevent sagging breasts . After a massage , you are advised to use a bra all day until night , till the next day in the shower . Herbal supplements A study found that eating fennel seeds in the form of supplements can increase breast size . This is because the fennel seeds give estrogen-like effects that cause retention ( detention ) of fluid in the breast so that the breast size can be increased . Not only that , traditionally fennel seeds are also good for increasing milk production , increase libido , a

Linus Pauling Institute at Oregon State University

Vitamin D from dietary intake and sunlight exposure and the risk of hormone-receptor-defined breast cancer. Blackmore KM, Lesosky M, Barnett H, Raboud JM, Vieth R, Knight JA. Am J Epidemiol. 2008 Oct 15;168(8):915-24. Epub 2008 Aug 27. PMID: 18756015 doi:10.1093/aje/kwn198 This study suggests that vitamin D is associated with a reduced risk of breast cancer regardless of ER/PR status of the tumor. Future studies with a larger number of receptor-negative and mixed tumors are required.